ISDA: 9I8I

Deposition Date 2025-02-05

Release Date 2025-02-26

Last Version Date 2026-04-01

Entry Detail

PDB ID:

9I8I

Keywords:

VIRUS

Title:

cryoEM structure of HIV-1 KAKA/G225R mature CA hexamer

Biological Source:

Source Organism(s):

HIV-1 06TG.HT008 (Taxon ID: 587638)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.75 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:HIV-1 KAKA/G225R CA hexamer
Chain IDs:A, B (auth: F), C (auth: E), D, E (auth: C), F (auth: B)
Chain Length:231
Number of Molecules:6
Biological Source:HIV-1 06TG.HT008

UniProt ID:D2ECD8 Pfam ID:PF00607, PF19317

Ligand Molecules

Primary Citation

Structural basis for HIV-1 capsid adaption to a deficiency in IP6 packaging.

Zhu, Y, Kleinpeter, A.B, Rey, J.S, Shen, J, Shen, Y, Xu, J, Hardenbrook, N, Chen, L, Lucic, A, Perilla, J.R, Freed, E.O, Zhang, P, Zhu, Y, Kleinpeter, A.B, Rey, J.S, Shen, J, Shen, Y, Xu, J, Hardenbrook, N, Chen, L, Lucic, A, Perilla, J.R, Freed, E.O, Zhang, P.Show

Nat Commun 16 8152 8152 (2025)

PMID: 40890096 DOI: 10.1038/s41467-025-63363-9

Primary Citation of related structures

Feedback Form