ISDA: 28YJ

Deposition Date 2026-03-02

Release Date 2026-03-18

Last Version Date 2026-04-08

Entry Detail

PDB ID:

28YJ

Keywords:

STRUCTURAL PROTEIN

Title:

Molecular basis of ZPD homopolymerization: cryo-EM structure of a native vertebrate egg coat filament

Biological Source:

Source Organism(s):

Gallus gallus (Taxon ID: 9031)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

4.60 Å

Aggregation State:

FILAMENT

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Uromodulin
Chain IDs:A, B, C, D
Chain Length:324
Number of Molecules:4
Biological Source:Gallus gallus

Ligand Molecules

Primary Citation

AlphaFold as a prior: experimental structure determination conditioned on a pretrained neural network

Fadini, A, Li, M, McCoy, A.J, Banjara, S, Okumura, H, Napier, E, Fontana, P, Khan, A.R, Jovine, L, Terwilliger, T.C, Read, R.J, Hekstra, D.R, AlQuraishi, M, Okumura, H, Kohno, Y, Iwata, Y, Mori, H, Aoki, N, Sato, C, Kitajima, K, Nadano, D, Matsuda, T, Nishio, S, Okumura, H, Matsuda, T, Stsiapanava, A, Xu, C, Brunati, M, Zamora-Caballero, S, Schaeffer, C, Bokhove, M, Han, L, Hebert, H, Carroni, M, Yasumasu, S, Rampoldi, L, Wu, B, Jovine, L, Nishio, S, Emori, C, Wiseman, B, Fahrenkamp, D, Dioguardi, E, Zamora-Caballero, S, Bokhove, M, Han, L, Stsiapanava, A, Algarra, B, Lu, Y, Kodani, M, Bainbridge, R.E, Komondor, K.M, Carlson, A.E, Landreh, M, de Sanctis, D, Yasumasu, S, Ikawa, M, Jovine, L.Show

Nat.Methods ? ? ? (2026)

DOI: 10.1038/s41592-026-03047-4

Primary Citation of related structures

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