ISDA: 10GW

Deposition Date 2026-01-19

Release Date 2026-03-18

Last Version Date 2026-03-18

Entry Detail

PDB ID:

10GW

Keywords:

OXIDOREDUCTASE

Title:

Crystal structure of tetrameric 6-phosphogluconate dehydrogenase from Gluconobacter oxydans in complex with 6-phosphogluconate

Biological Source:

Source Organism(s):

Gluconobacter oxydans (Taxon ID: 442)

Expression System(s):

Escherichia coli 'bl21-gold(de3)plyss ag'

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.00 Å

R-Value Free:

0.22

R-Value Work:

0.19

R-Value Observed:

0.19

Space Group:

P 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:6-phosphogluconate dehydrogen
Gene (Uniprot):GOX1705
Chain IDs:A, B, C, D
Chain Length:353
Number of Molecules:4
Biological Source:Gluconobacter oxydans

UniProt ID:G5EBD7 Pfam ID:PF03446, PF00393 EC:1.1.1.343

Ligand Molecules

6PG

Primary Citation

Structural, dynamic, and evolutionary determinants of substrate binding in the tetrameric 6-phosphogluconate dehydrogenase from Gluconobacter oxydans.

Maturana, P, Villalobos, P, Roversi, P, Cabrera, R, Liebschner, D, Afonine, P.V, Baker, M.L, Bunkoczi, G, Chen, V.B, Croll, T.I, Hintze, B, Hung, L.W, Jain, S, McCoy, A.J, Moriarty, N.W, Oeffner, R.D, Poon, B.K, Prisant, M.G, Read, R.J, Richardson, J.S, Richardson, D.C, Sammito, M.D, Sobolev, O.V, Stockwell, D.H, Terwilliger, T.C, Urzhumtsev, A.G, Videau, L.L, Williams, C.J, Adams, P.D.Show

Arch.Biochem.Biophys. 779 110779 110779 (2026)

PMID: 41765070 DOI: 10.1016/j.abb.2026.110779

Primary Citation of related structures

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