Search Count: 20
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Discovery And Characterisation Of 2-Anilino-4-(Thiazol-5-Yl) Pyrimidine Transcriptional Cdk Inhibitors As Anticancer Agents
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2010-11-10 Classification: TRANSFERASE Ligands: CDK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-11-10
Ligands: CDK
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Discovery And Characterisation Of 2-Anilino-4-(Thiazol-5-Yl) Pyrimidine Transcriptional Cdk Inhibitors As Anticancer Agents
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2010-11-10 Classification: TRANSFERASE Ligands: Y8L |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-11-10
Ligands: Y8L
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Truncation And Optimisation Of Peptide Inhibitors Of Cdk2, Cyclin A Through Structure Guided Design
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2010-02-16 Classification: CELL CYCLE Ligands: X1N |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2010-02-16
Ligands: X1N
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Nmr Structure Of Unliganded Mdm2
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Organism: Homo sapiens
Method: SOLUTION NMR
Release Date: 2005-06-28
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Structural And Biochemical Studies Of Human Pcna Complexes Provide The Basis For Association With Cdk/Cyclin And Rationale For Inhibitor Design
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2005-01-13 Classification: DNA BINDING PROTEIN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2005-01-13
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Native Human Pcna
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2005-01-13 Classification: DNA BINDING PROTEIN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2005-01-13
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Native Human Pcna
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.15 Å Release Date: 2005-01-13 Classification: DNA BINDING PROTEIN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2005-01-13
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Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor 3-[4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.53 Å Release Date: 2004-04-13 Classification: TRANSFERASE Ligands: CK5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2004-04-13
Ligands: CK5
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Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor 4-[4-(4-Methyl-2-Methylamino-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2004-04-13 Classification: TRANSFERASE Ligands: CK6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2004-04-13
Ligands: CK6
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Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor [4-(2-Amino-4-Methyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(3-Nitro-Phenyl)-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2004-04-13 Classification: TRANSFERASE Ligands: CK7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2004-04-13
Ligands: CK7
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Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor N-[4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-N',N'-Dimethyl-Benzene-1,4-Diamine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2004-04-13 Classification: TRANSFERASE Ligands: CK8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2004-04-13
Ligands: CK8
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Cyclin A Binding Groove Inhibitor H-Arg-Arg-Leu-Ile-Phe-Nh2
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2003-12-11 Classification: TRANSFERASE/TRANSFERASE INHIBITOR |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2003-12-11
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Cyclin A Binding Groove Inhibitor Ac-Arg-Arg-Leu-Asn-(M-Cl-Phe)-Nh2
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2003-12-11 Classification: TRANSFERASE/TRANSFERASE INHIBITOR |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2003-12-11
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Cyclin A Binding Groove Inhibitor H-Cit-Cit-Leu-Ile-(P-F-Phe)-Nh2
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2003-12-11 Classification: TRANSFERASE/TRANSFERASE INHIBITOR |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2003-12-11
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Cyclin A Binding Groove Inhibitor H-Arg-Arg-Leu-Asn-(P-F-Phe)-Nh2
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2003-12-11 Classification: TRANSFERASE/TRANSFERASE INHIBITOR |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2003-12-11
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Apo Structure Of Human Cyclin-Dependent Kinase 2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2003-12-09 Classification: TRANSFERASE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2003-12-09
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Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2003-12-09 Classification: TRANSFERASE Ligands: CK1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2003-12-09
Ligands: CK1
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Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor 4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2003-12-09 Classification: TRANSFERASE Ligands: CK2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2003-12-09
Ligands: CK2
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Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor N-[4-(2,4-Dimethyl-Thiazol-5-Yl)Pyrimidin-2-Yl]-N'-Hydroxyiminoformamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2003-12-09 Classification: TRANSFERASE Ligands: CK3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2003-12-09
Ligands: CK3
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Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor [4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(4-Trifluoromethyl-Phenyl)-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2003-12-09 Classification: TRANSFERASE Ligands: CK4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2003-12-09
Ligands: CK4