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9PZF image
Structure Of Kras G12C Bound To Compound 4
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.84 Å Release Date: 2026-03-11
Classification: ONCOPROTEIN
Ligands: A1CQ2, GDP, MG

9PZY image
Structure Of Kras G12C Bound To Divarasib (Gdc6036)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.17 Å Release Date: 2026-03-11
Classification: ONCOPROTEIN
Ligands: GDP, MG, DMS, EDO, A1AWR, PEG

6VBN image
Crystal Structure Of Htdo2 Bound To Inhibitor Gne1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:3.18 Å Release Date: 2020-05-06
Classification: OXIDOREDUCTASE/Inhibitor
Ligands: HEM, QVY

6N77 image
Structure Of The Human Jak1 Kinase Domain With Compound 15
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.64 Å Release Date: 2019-04-24
Classification: IMMUNE SYSTEM
Ligands: KEJ, GOL

6N78 image
Structure Of The Human Jak1 Kinase Domain With Compound 21
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.83 Å Release Date: 2019-04-24
Classification: IMMUNE SYSTEM
Ligands: KEP, GOL

6N79 image
Structure Of The Human Jak1 Kinase Domain With Compound 20
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.27 Å Release Date: 2019-04-24
Classification: IMMUNE SYSTEM
Ligands: KES, GOL

6N7A image
Structure Of The Human Jak1 Kinase Domain With Compound 39
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.33 Å Release Date: 2019-04-24
Classification: IMMUNE SYSTEM
Ligands: GOL, KEV

6N7B image
Structure Of The Human Jak1 Kinase Domain With Compound 38
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.81 Å Release Date: 2019-04-24
Classification: IMMUNE SYSTEM
Ligands: KEY, GOL

6N7C image
Structure Of The Human Jak1 Kinase Domain With Compound 56
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.69 Å Release Date: 2019-04-24
Classification: IMMUNE SYSTEM
Ligands: KF1, GOL

6N7D image
Structure Of The Human Jak1 Kinase Domain With Compound 54
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.78 Å Release Date: 2019-04-24
Classification: IMMUNE SYSTEM
Ligands: KF4, GOL

5TP9 image
Structure Of The Human Glun1/Glun2A Lbd In Complex With Compound 2 (Gne9178)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.40 Å Release Date: 2016-11-30
Classification: TRANSPORT PROTEIN
Ligands: ACT, GLU, 7H0, CA, GLY

5TPA image
Structure Of The Human Glun1/Glun2A Lbd In Complex With Compound 9 (Gne3500)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.48 Å Release Date: 2016-11-30
Classification: TRANSPORT PROTEIN
Ligands: GLU, 7H2, GLY

5KIT image
Crystal Structure Of Nicotinamide Phosphoribosyltransferase (Nampt) In Complex With Inhibitors 37
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.60 Å Release Date: 2016-08-31
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Ligands: 6TA, PO4, EDO

5KDT image
Structure Of The Human Glun1/Glun2A Lbd In Complex With Gne0723
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.44 Å Release Date: 2016-07-13
Classification: TRANSPORT PROTEIN
Ligands: ACT, GLU, 6RV, GLY

5I2K image
Structure Of The Human Glun1/Glun2A Lbd In Complex With 7-{[Ethyl(4-Fluorophenyl)Amino]Methyl}-N,2-Dimethyl-5-Oxo-5H-[1,3]Thiazolo[3,2-A]Pyrimidine-3-Carboxamide (Compound 19)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.86 Å Release Date: 2016-03-16
Classification: TRANSPORT PROTEIN
Ligands: GLU, GLY, 67H

5I2N image
Structure Of The Human Glun1/Glun2A Lbd In Complex With N-Ethyl-7-{[2-Fluoro-3-(Trifluoromethyl)Phenyl]Methyl}-2-Methyl-5-Oxo-5H-[1,3]Thiazolo[3,2-A]Pyrimidine-3-Carboxamide (Compound 29)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.12 Å Release Date: 2016-03-16
Classification: TRANSPORT PROTEIN
Ligands: CA, GLU, 67J, EPE, GLY

4RFM image
Itk Kinase Domain In Complex With Compound 1 N-{1-[(1,1-Dioxo-1-Thian-2-Yl)(Phenyl)Methyl]-1H- Pyrazol-4-Yl}-5,5-Difluoro-5A-Methyl-1H,4H,4Ah,5H,5Ah,6H-Cyclopropa[F]Indazole-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.10 Å Release Date: 2015-04-29
Classification: TRANSFERASE/INHIBITOR
Ligands: 3P6

4WQ6 image
The Crystal Structure Of Human Nicotinamide Phosphoribosyltransferase (Nampt) In Complex With N-(4-{(S)-[1-(2-Methylpropyl)Piperidin-4-Yl]Sulfinyl}Benzyl)Furo[2,3-C]Pyridine-2-Carboxamide Inhibitor (Compound 21)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.72 Å Release Date: 2015-02-11
Classification: Transferase/Transferase inhibitor
Ligands: 3TQ, PO4, EDO

4PQN image
Itk Kinase Domain With Compound Gne-9822
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.71 Å Release Date: 2014-07-02
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Ligands: 2W6, P4G

4PRJ image
Aurora A Kinase Domain With Compound 2 (N-[1-(3-Cyanobenzyl)-1H-Pyrazol-4-Yl]-6-(1H-Pyrazol-4-Yl)-1H-Indazole-3-Carboxamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.80 Å Release Date: 2014-07-02
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Ligands: 2VU
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