Search Count: 76
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Structure-Guided Design Of Picomolar-Level Macrocyclic Trpc5 Channel Inhibitors With Antidepressant Activity
Organism: Mus musculus
Method: ELECTRON MICROSCOPY Release Date: 2025-12-24 Classification: MEMBRANE PROTEIN Ligands: ZN, CA, A1EH7 |
Organism: Mus musculus
Method: ELECTRON MICROSCOPY
Release Date: 2025-12-24
Ligands: ZN, CA, A1EH7
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Structure-Guided Design Of Picomolar-Level Macrocyclic Trpc5 Channel Inhibitors With Antidepressant Activity
Organism: Mus musculus
Method: ELECTRON MICROSCOPY Release Date: 2025-12-03 Classification: MEMBRANE PROTEIN Ligands: ZN, CA, A1EH7 |
Organism: Mus musculus
Method: ELECTRON MICROSCOPY
Release Date: 2025-12-03
Ligands: ZN, CA, A1EH7
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Structural Mechanism Of Human Hcn1 Hyperpolarization-Activated Channel Inhibition By Ivabradine
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2025-10-29 Classification: MEMBRANE PROTEIN Ligands: CLR, VNZ |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2025-10-29
Ligands: CLR, VNZ
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Brd4 In Complex With Compound7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.59 Å Release Date: 2025-10-01 Classification: DNA BINDING PROTEIN Ligands: A1D95, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-10-01
Ligands: A1D95, CL
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Sertraline Enhances The Deubiquitinase Activity Of Usp7 By Binding To Its Switching Loop Region
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.46 Å Release Date: 2025-03-12 Classification: HYDROLASE Ligands: SRE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-03-12
Ligands: SRE
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Sertraline Enhances The Deubiquitinase Activity Of Usp7 By Binding To Its Switching Loop Region
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.78 Å Release Date: 2025-03-12 Classification: HYDROLASE Ligands: XB7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-03-12
Ligands: XB7
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Cryo-Em Structure Of Human Hcn3 Channel With Camp
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2024-11-13 Classification: MEMBRANE PROTEIN Ligands: CMP |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2024-11-13
Ligands: CMP
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Ripk2 In Complex With K252
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.26 Å Release Date: 2024-11-13 Classification: IMMUNE SYSTEM Ligands: 6IL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-11-13
Ligands: 6IL
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Crystal Structure Of Brd4-Bd1 Bound With Di106
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.13 Å Release Date: 2024-07-24 Classification: TRANSCRIPTION Ligands: X3L |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-07-24
Ligands: X3L
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Cryo-Em Structure Of Human Hcn3 Channel In Apo State
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2024-04-10 Classification: MEMBRANE PROTEIN Ligands: VX9 |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2024-04-10
Ligands: VX9
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Bromodomain And Extra-Terminal Domain (Bet) Brd4
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.45 Å Release Date: 2023-10-04 Classification: DNA BINDING PROTEIN Ligands: OWO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-04
Ligands: OWO
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Bromodomain And Extra-Terminal Domain (Bet) Brd4
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.57 Å Release Date: 2023-10-04 Classification: DNA BINDING PROTEIN Ligands: OWO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-10-04
Ligands: OWO
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Vismodegib Binds To The Catalytical Domain Of Human Ubiquitin-Specific Protease 28
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.85 Å Release Date: 2023-05-03 Classification: HYDROLASE Ligands: VIS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-05-03
Ligands: VIS
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Discovery Of Selective Brd4 Bd1 Inhibitor Based On [1,2,4] Triazolo [4,3-B] Pyridazine Scaffold
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.44 Å Release Date: 2023-03-22 Classification: DNA BINDING PROTEIN Ligands: 97F |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-03-22
Ligands: 97F
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Nsd2-Pwwp1 Domain Bound With An Imidazol-5-Yl Benzonitrile Compound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.09 Å Release Date: 2022-07-06 Classification: TRANSFERASE Ligands: 7QC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-07-06
Ligands: 7QC
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Carm1 Bound With Compound 9
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2021-11-24 Classification: TRANSFERASE Ligands: XJ3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-11-24
Ligands: XJ3
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Carm1 Bound With Compound 43
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2021-11-24 Classification: TRANSFERASE Ligands: XJ4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-11-24
Ligands: XJ4
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Characterization Of Peptide Ligands Against Wdr5 Isolated Using Phage Display Technique
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.03 Å Release Date: 2021-02-10 Classification: PEPTIDE BINDING PROTEIN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-02-10
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Brd4 Bd1 Bound With Compound 10
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.62 Å Release Date: 2020-12-16 Classification: GENE REGULATION Ligands: EDF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-12-16
Ligands: EDF
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Brd4-Bd1 Bound With Compound 40
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.76 Å Release Date: 2020-12-16 Classification: GENE REGULATION Ligands: EE9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-12-16
Ligands: EE9