Search Count: 19
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Ire1 Kinase/Rnase In Complex With Imidazo[1,2-B]Pyridazin-8-Amine Compound 33
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.73 Å Release Date: 2019-02-27 Classification: SIGNALING PROTEIN Ligands: GUK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-02-27
Ligands: GUK
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Ire1 Alpha In Complex With Imidazo[1,2-B]Pyridazin-8-Amine Compound 2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.14 Å Release Date: 2019-02-27 Classification: TRANSFERASE Ligands: GXK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-02-27
Ligands: GXK
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Cct068127 In Complex With Cdk2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.30 Å Release Date: 2017-12-20 Classification: CELL CYCLE/INHIBITOR Ligands: 8QT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-12-20
Ligands: 8QT
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Multi-Parameter Lead Optimization To Give An Oral Chk1 Inhibitor Clinical Candidate: (R)-5-((4-((Morpholin-2-Ylmethyl)Amino)-5-(Trifluoromethyl)Pyridin-2-Yl)Amino)Pyrazine-2-Carbonitrile (Cct245737)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.91 Å Release Date: 2016-05-25 Classification: TRANSFERASE Ligands: 5UY, EDO, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-05-25
Ligands: 5UY, EDO, GOL
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Structure Of Pka-Pkb Chimera Complexed With (1S)-2-Amino-1-(4- Chlorophenyl)-1-(4-(1H-Pyrazol-4-Yl)Phenyl)Ethan-1-Ol
Organism: Bos taurus, Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2012-07-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: RKD |
Organism: Bos taurus, Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-07-25
Ligands: RKD
 |
Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.01 Å Release Date: 2012-01-11 Classification: TRANSFERASE Ligands: YM3, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-01-11
Ligands: YM3, EDO
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Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2012-01-11 Classification: TRANSFERASE Ligands: 4YM, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-01-11
Ligands: 4YM, EDO
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Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.03 Å Release Date: 2012-01-11 Classification: TRANSFERASE Ligands: YM5, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-01-11
Ligands: YM5, EDO
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Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.01 Å Release Date: 2012-01-11 Classification: TRANSFERASE Ligands: YM6, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-01-11
Ligands: YM6, EDO
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Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.81 Å Release Date: 2012-01-11 Classification: TRANSFERASE Ligands: YM7, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-01-11
Ligands: YM7, EDO
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Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2012-01-11 Classification: TRANSFERASE Ligands: YM8, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-01-11
Ligands: YM8, EDO
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Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.48 Å Release Date: 2009-07-28 Classification: TRANSFERASE Ligands: ZYQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-07-28
Ligands: ZYQ
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Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.43 Å Release Date: 2009-07-28 Classification: TRANSFERASE Ligands: ZYR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-07-28
Ligands: ZYR
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Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2009-07-28 Classification: TRANSFERASE Ligands: ZYS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-07-28
Ligands: ZYS
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Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.55 Å Release Date: 2009-07-28 Classification: TRANSFERASE Ligands: ZYT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-07-28
Ligands: ZYT
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Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2009-07-28 Classification: TRANSFERASE Ligands: ZYU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-07-28
Ligands: ZYU
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Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.01 Å Release Date: 2009-07-28 Classification: TRANSFERASE Ligands: ZYV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-07-28
Ligands: ZYV
 |
Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.43 Å Release Date: 2009-07-28 Classification: TRANSFERASE Ligands: ZYW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-07-28
Ligands: ZYW
 |
Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2009-07-28 Classification: TRANSFERASE Ligands: ZY6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-07-28
Ligands: ZY6