Search Count: 13
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Crystal Structure Of The Ph-Th-Kinase Construct Of Bruton'S Tyrosine Kinase (Btk)
Organism: Bos taurus
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2015-03-18 Classification: TRANSFERASE Ligands: ZN, 746, CA |
Organism: Bos taurus
Method: X-RAY DIFFRACTION
Release Date: 2015-03-18
Ligands: ZN, 746, CA
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Crystal Structure Of The Ph-Th Module Of Bruton'S Tyrosine Kinase Bound To Inositol Hexakisphosphate
Organism: Bos taurus
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2015-03-18 Classification: TRANSFERASE Ligands: IHP, ZN |
Organism: Bos taurus
Method: X-RAY DIFFRACTION
Release Date: 2015-03-18
Ligands: IHP, ZN
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Crystal Structure Of The Kinase Domain Of Bruton'S Tyrosine Kinase With Mutations In The Activation Loop
Organism: Bos taurus
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2015-03-18 Classification: TRANSFERASE Ligands: 746, GOL, BME, PE4 |
Organism: Bos taurus
Method: X-RAY DIFFRACTION
Release Date: 2015-03-18
Ligands: 746, GOL, BME, PE4
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Crystal Structure Of An Auto-Inhibited Form Of Bruton'S Tryrosine Kinase
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2015-02-25 Classification: TRANSFERASE Ligands: AU |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2015-02-25
Ligands: AU
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Crystal Structure Of A 3-Oxoacyl-[Acyl-Carrier Protein] Reductase From Brucella Melitensis
Organism: Brucella melitensis
Method: X-RAY DIFFRACTION Resolution:1.65 Å Release Date: 2014-02-12 Classification: OXIDOREDUCTASE Ligands: CL, MPD |
Organism: Brucella melitensis
Method: X-RAY DIFFRACTION
Release Date: 2014-02-12
Ligands: CL, MPD
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Discovery Of A Stable Macrocyclic O-Aminobenzamide Hsp90 Inhibitor Capable Of Significantly Decreasing Tumor Volume In A Mouse Xenograft Model.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.57 Å Release Date: 2011-07-13 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 06T |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-07-13
Ligands: 06T
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Discovery Of A Macrocyclic O-Aminobenzamide Hsp90 Inhibitor With Heterocyclic Tether That Shows Extended Biomarker Activity And In Vivo Efficacy In A Mouse Xenograft Model.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.58 Å Release Date: 2011-06-08 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 06J |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-06-08
Ligands: 06J
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Macrocyclic Lactams As Potent Hsp90 Inhibitors With Excellent Tumor Exposure And Extended Biomarker Activity.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.58 Å Release Date: 2011-05-11 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 06H |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-05-11
Ligands: 06H
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Design And Sar Of Macrocyclic Hsp90 Inhibitors With Increased Metabolic Stability And Potent Cell-Proliferation Activity
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.57 Å Release Date: 2011-04-06 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 05S, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-04-06
Ligands: 05S, DMS
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Discovery Of Benzisoxazoles As Potent Inhibitors Of Chaperone Hsp90
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2008-07-08 Classification: CHAPERONE Ligands: BXZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-07-08
Ligands: BXZ
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Discovery Of Benzisoxazoles As Potent Inhibitors Of Chaperone Hsp90
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2008-07-08 Classification: CHAPERONE Ligands: CXZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-07-08
Ligands: CXZ
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Structure Of An Unliganded And Fully-Glycosylated Siv Gp120 Envelope Glycoprotein
Organism: Simian immunodeficiency virus
Method: X-RAY DIFFRACTION Resolution:4.00 Å Release Date: 2005-02-17 Classification: VIRUS PROTEIN Ligands: NAG |
Organism: Simian immunodeficiency virus
Method: X-RAY DIFFRACTION
Release Date: 2005-02-17
Ligands: NAG
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Crystal Structure At 1.8 Angstrom Of Cdp-D-Glucose 4,6-Dehydratase From Yersinia Pseudotuberculosis
Organism: Yersinia pseudotuberculosis
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2004-03-30 Classification: LYASE Ligands: NAD |
Organism: Yersinia pseudotuberculosis
Method: X-RAY DIFFRACTION
Release Date: 2004-03-30
Ligands: NAD