Search Count: 39
 |
Crystal Structure Of The Mertk Kinase Domain With Sa4488
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.07 Å Release Date: 2024-10-09 Classification: TRANSFERASE Ligands: A1APF, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-09
Ligands: A1APF, CL
 |
Discovery Of Spirohydantoins As Selective, Orally Bioavailable Inhibitors Of P300/Cbp Histone Acetyltransferases
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.61 Å Release Date: 2021-03-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: Y2P |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-03-17
Ligands: Y2P
 |
Brd4_Bromodomain1 Complex With Pyrrolopyridone Compound 18
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.43 Å Release Date: 2020-05-06 Classification: SIGNALING PROTEIN Ligands: QYV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-05-06
Ligands: QYV
 |
Brd4_Bromodomain2 Complex With Pyrrolopyridone Compound 18
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.12 Å Release Date: 2020-05-06 Classification: SIGNALING PROTEIN Ligands: QYV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-05-06
Ligands: QYV
 |
Brd2_Bromodomain2 Complex With Pyrrolopyridone Compound 27
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2020-05-06 Classification: SIGNALING PROTEIN Ligands: QYY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-05-06
Ligands: QYY
 |
Brd4_Bromodomain1 Complex With Pyrrolopyridone Compound 27
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.39 Å Release Date: 2020-05-06 Classification: SIGNALING PROTEIN Ligands: QYY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-05-06
Ligands: QYY
 |
Brd2_Bromodomain1 Complex With Inhibitor 744
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2020-01-29 Classification: SIGNALING PROTEIN Ligands: EDO, HWV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-29
Ligands: EDO, HWV
 |
Brd2_Bromodomain2 Complex With Inhibitor 744
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.44 Å Release Date: 2019-07-31 Classification: SIGNALING PROTEIN Ligands: HWV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-31
Ligands: HWV
 |
Novel, Potent, Selective And Brain Penetrant Phosphodiesterase 10A Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.06 Å Release Date: 2019-01-09 Classification: HYDROLASE Ligands: ZN, MG, JY4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-01-09
Ligands: ZN, MG, JY4
 |
Novel, Potent, Selective And Brain Penetrant Phosphodiesterase 10A Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.36 Å Release Date: 2019-01-09 Classification: HYDROLASE Ligands: ZN, MG, JY7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-01-09
Ligands: ZN, MG, JY7
 |
Novel Modes Of Inhibition Of Wild-Type Idh1: Direct Covalent Modification Of His315 With Cmpd1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.65 Å Release Date: 2018-07-25 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor Ligands: CA, ICT, DWP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-07-25
Ligands: CA, ICT, DWP
 |
Novel Binding Modes Of Inhibition Of Wild-Type Idh1: Allosteric Inhibition With Cmpd2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2018-07-25 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor Ligands: LMR, MG, K32 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-07-25
Ligands: LMR, MG, K32
 |
Novel Modes Of Inhibition Of Wild-Type Idh1: Non-Equivalent Allosteric Inhibition With Cmpd3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.01 Å Release Date: 2018-07-25 Classification: oxidoreductase/oxidoreductase inhibitor Ligands: NAP, DWM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-07-25
Ligands: NAP, DWM
 |
Novel Modes Of Inhibition Of Wild-Type Idh1:Direct Covalent Modification Of His315 With Cmpd11
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2018-07-25 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor Ligands: MG, ICT, DWJ, NAP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-07-25
Ligands: MG, ICT, DWJ, NAP
 |
Novel Modes Of Inhibition Of Wild-Type Idh1: Direct Covalent Modification Of His315 With Cmpd13
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.02 Å Release Date: 2018-07-25 Classification: oxidoreductase/oxidoreductase inhibitor Ligands: ICT, DWG, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-07-25
Ligands: ICT, DWG, CA
 |
Novel Modes Of Inhibition Of Wild-Type Idh1: Direct Covalent Modification Of His315 With Cmpd15
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.92 Å Release Date: 2018-07-25 Classification: oxidoreductase/oxidoreductase inhibitor Ligands: CA, ICT, DWS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-07-25
Ligands: CA, ICT, DWS
 |
The Novel P300/Cbp Inhibitor A-485 Uncovers A Unique Mechanism Of Action To Target Ar In Castrate Resistant Prostate Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2017-09-27 Classification: transferase/transferase INHIBITOR Ligands: 6TF, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-27
Ligands: 6TF, NA
 |
Polycomb Protein Eed In Complex With Inhibitor: (3R,4S)-1-[(2-Methoxyphenyl)Methyl]-N,N-Dimethyl-4-(1-Methylindol-3-Yl)Pyrrolidin-3-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.28 Å Release Date: 2017-03-15 Classification: PROTEIN BINDING, INHIBITOR Ligands: LQD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-15
Ligands: LQD
 |
Polycomb Protein Eed In Complex With Inhibitor: 2-[4-(4-{(3S,4R)-4-(Dimethylamino)-1-[(2-Fluoro-6-Methylphenyl)Methyl]Pyrrolidin-3-Yl}Phenyl)-1H-Pyrazol-1-Yl]Acetamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.64 Å Release Date: 2017-03-15 Classification: PROTEIN BINDING, INHIBITOR Ligands: 7XG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-15
Ligands: 7XG
 |
Polycomb Protein Eed In Complex With Inhibitor: (3R,4S)-1-[(2-Bromo-6-Fluorophenyl)Methyl]-N,N-Dimethyl-4-(1-Methyl-1H-Indol-3-Yl)Pyrrolidin-3-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.45 Å Release Date: 2017-03-15 Classification: PROTEIN BINDING/INHIBITOR Ligands: 82D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-15
Ligands: 82D