Search Count: 47
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Crystal Structure Of Cyp46A1 With [(1R,5S)-3-Oxa-8-Azabicyclo[3.2.1]Octan-8-Yl][(4R,8M)-8-(1,3-Oxazol-5-Yl)-6-(Trifluoromethyl)Imidazo[1,2-A]Pyridin-3-Yl]Methanone (Compound 3K)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.67 Å Release Date: 2025-07-02 Classification: HYDROLASE/INHIBITOR Ligands: HEM, A1BZE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-07-02
Ligands: HEM, A1BZE
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Crystal Structure Of Cyp46A1 With (Morpholin-4-Yl)[(4R,8M)-8-(1,3-Oxazol-5-Yl)-6-(Trifluoromethyl)Imidazo[1,2-A]Pyridin-3-Yl]Methanone (Compound 2H)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2025-07-02 Classification: HYDROLASE/INHIBITOR Ligands: HEM, A1BZD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-07-02
Ligands: HEM, A1BZD
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Crystal Structure Of Cyp46A1 With Cyclopropyl[(4M)-4-(1,3-Oxazol-5-Yl)-6-(Trifluoromethyl)-1H-Indol-1-Yl]Methanone (Compound 2B)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2025-07-02 Classification: HYDROLASE/INHIBITOR Ligands: HEM, A1BZC, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-07-02
Ligands: HEM, A1BZC, EDO
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Crystal Structure Of Cyp46A1 With 3-Chloro-N-[(3M)-3-(1,3-Oxazol-5-Yl)Phenyl]-N-(Propan-2-Yl)Benzene-1-Sulfonamide (Compound 2)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.29 Å Release Date: 2025-04-23 Classification: HYDROLASE/INHIBITOR Ligands: HEM, A1BZB, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-04-23
Ligands: HEM, A1BZB, EDO
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Crystal Structure Of Cyp46A1 With 3-Chloro-N-[(3M)-3-(1,3-Oxazol-5-Yl)-5-(Trifluoromethyl)Phenyl]Benzamide (Compound 3F)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2025-04-23 Classification: HYDROLASE/INHIBITOR Ligands: HEM, A1BZA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-04-23
Ligands: HEM, A1BZA
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Crystal Structure Of Cyp46A1 With N-[6-(1,3-Oxazol-5-Yl)-4-(Trifluoromethyl)Pyridin-2-Yl]Cyclopropanecarboxamide (Compound 4L)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2025-04-23 Classification: HYDROLASE/INHIBITOR Ligands: HEM, A1BY9, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-04-23
Ligands: HEM, A1BY9, EDO
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Co-Complex Cyp46A1 With 0420 (Compound 6)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.63 Å Release Date: 2022-02-23 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: HEM, EDO, 04Y, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-02-23
Ligands: HEM, EDO, 04Y, GOL
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Co-Complex Cyp46A1 With 0431 (Compound 17)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2022-02-23 Classification: HYDROLASE Ligands: HEM, 05D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-02-23
Ligands: HEM, 05D
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Co-Complex Cyp46A1 With 7742 (Soticlestat/Tak-935))
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2021-08-25 Classification: HYDROLASE Ligands: HEM, YBS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-08-25
Ligands: HEM, YBS
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Co-Complex Cyp46A1 With 8114 (3F)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2021-08-25 Classification: HYDROLASE Ligands: HEM, YCJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-08-25
Ligands: HEM, YCJ
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Co-Complex Cyp46A1 With 9129 (1B)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2021-08-25 Classification: HYDROLASE Ligands: HEM, YCG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-08-25
Ligands: HEM, YCG
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Crystal Structure Of Rip1 Kinase Bound To Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2018-03-21 Classification: Transferase/Transferase Inhibitor Ligands: EJY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-21
Ligands: EJY
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Structure Based Design Of Rip1 Kinase Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.52 Å Release Date: 2018-03-21 Classification: Transferase/Transferase Inhibitor Ligands: EJP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-21
Ligands: EJP
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Structure Of Protein Kinase C Theta With Compound 10: 2,2-Dimethyl-7-(2-Oxidanylidene-3~{H}-Imidazo[4,5-B]Pyridin-1-Yl)-1-(Phenylmethyl)-3~{H}-Quinazolin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2016-05-11 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 5VS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-05-11
Ligands: 5VS
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Crystal Structure Of Trypanosoma Cruzi Spermidine Synthase In Complex With (2S)-N-Methyl-N-Phenyl-2,3-Dihydro-1,4-Benzodioxine- 2-Carboxamid
Organism: Trypanosoma cruzi (strain cl brener)
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2015-09-16 Classification: TRANSFERASE Ligands: S4M, 4JW |
Organism: Trypanosoma cruzi (strain cl brener)
Method: X-RAY DIFFRACTION
Release Date: 2015-09-16
Ligands: S4M, 4JW
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Crystal Structure Of Trypanosoma Cruzi Spermidine Synthase In Complex With Quinolin-8-Yl Piperidine-1-Carboxylate
Organism: Trypanosoma cruzi (strain cl brener)
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2015-09-16 Classification: TRANSFERASE Ligands: S4M, 4K2 |
Organism: Trypanosoma cruzi (strain cl brener)
Method: X-RAY DIFFRACTION
Release Date: 2015-09-16
Ligands: S4M, 4K2
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Crystal Structure Of Trypanosoma Cruzi Spermidine Synthase In Complex With 2-Phenyl-1,2-Thiazol-3(2H)-One
Organism: Trypanosoma cruzi (strain cl brener)
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2015-09-16 Classification: TRANSFERASE Ligands: S4M, 4K3 |
Organism: Trypanosoma cruzi (strain cl brener)
Method: X-RAY DIFFRACTION
Release Date: 2015-09-16
Ligands: S4M, 4K3
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Crystal Structure Of Trypanosoma Cruzi Spermidine Synthase In Complex With Decarboxylated S-Adenosylmethionine
Organism: Trypanosoma cruzi (strain cl brener)
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2015-09-09 Classification: TRANSFERASE Ligands: S4M |
Organism: Trypanosoma cruzi (strain cl brener)
Method: X-RAY DIFFRACTION
Release Date: 2015-09-09
Ligands: S4M
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Crystal Structure Of Trypanosoma Cruzi Spermidine Synthase In Complex With Trans-4-Methylcyclohexylamine
Organism: Trypanosoma cruzi (strain cl brener)
Method: X-RAY DIFFRACTION Resolution:1.97 Å Release Date: 2015-09-09 Classification: TRANSFERASE Ligands: S4M, 4JU |
Organism: Trypanosoma cruzi (strain cl brener)
Method: X-RAY DIFFRACTION
Release Date: 2015-09-09
Ligands: S4M, 4JU
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Crystal Structure Of Trypanosoma Cruzi Spermidine Synthase In Complex With 2H-1,4-Benzothiazin-3-Amine
Organism: Trypanosoma cruzi (strain cl brener)
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2015-09-09 Classification: TRANSFERASE Ligands: S4M, 4JT |
Organism: Trypanosoma cruzi (strain cl brener)
Method: X-RAY DIFFRACTION
Release Date: 2015-09-09
Ligands: S4M, 4JT