Search Count: 21
 |
Identification Of Novel, Potent And Selective Gcn2 Inhibitors As First-In-Class Anti-Tumor Agents
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.61 Å Release Date: 2019-10-09 Classification: transferase/transferase inhibitor Ligands: KAV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-10-09
Ligands: KAV
 |
Identification Of Novel, Potent And Selective Gcn2 Inhibitors As First-In-Class Anti-Tumor Agents
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.01 Å Release Date: 2019-10-09 Classification: transferase/transferase inhibitor Ligands: KA4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-10-09
Ligands: KA4
 |
Identification Of Novel, Potent And Selective Gcn2 Inhibitors As First-In-Class Anti-Tumor Agents
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2019-10-09 Classification: transferase/transferase inhibitor Ligands: KA7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-10-09
Ligands: KA7
 |
Structure Of Rorgt In Complex With A Novel Isoquinoline Inverse Agonist.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.18 Å Release Date: 2018-03-21 Classification: transcription/agonist Ligands: MPD, E3S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-21
Ligands: MPD, E3S
 |
Structure Of Rorgt In Complex With A Novel Inverse Agonist Tak-828.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2018-03-21 Classification: transcription/agonist Ligands: MPD, E3V |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-03-21
Ligands: MPD, E3V
 |
Optimization Of 3,5-Disubstitued Piperidine: Discovery Of Non-Peptide Mimetics As An Orally Active Renin Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2017-10-18 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: NAG, 7EK, PGE, PEG, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-10-18
Ligands: NAG, 7EK, PGE, PEG, DMS
 |
Optimization Of 3,5-Disubstitued Piperidine: Discovery Of Non-Peptide Mimetics As An Orally Active Renin Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2017-10-18 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: NAG, 7EJ, DMS, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-10-18
Ligands: NAG, 7EJ, DMS, PEG
 |
Discovery Of Tak-272: A Novel, Potent And Orally Active Renin In-Hibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2017-07-05 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: NAG, 6VU, PGE, PEG, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-07-05
Ligands: NAG, 6VU, PGE, PEG, DMS
 |
Crystal Structure Of Ciap1 Bir3 Bound To T3258042
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2013-12-11 Classification: APOPTOSIS INHIBITOR Ligands: ZN, 2DX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-12-11
Ligands: ZN, 2DX
 |
Crystal Structure Of Ciap1 Bir3 Bound To T3450325
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.79 Å Release Date: 2013-12-11 Classification: APOPTOSIS INHIBITOR Ligands: ZN, 2DY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-12-11
Ligands: ZN, 2DY
 |
Crystal Structure Of Xiap Bir3 With T3256336
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.84 Å Release Date: 2013-01-30 Classification: LIGASE/LIGASE INHIBITOR Ligands: ZN, 1AQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-01-30
Ligands: ZN, 1AQ
 |
Crystal Structure Of Ciap1 Bir3 Bound To T3170284
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.25 Å Release Date: 2013-01-30 Classification: LIGASE/LIGASE INHIBITOR Ligands: ZN, 1BG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-01-30
Ligands: ZN, 1BG
 |
Crystal Structure Of Ciap1 Bir3 Bound To T3256336
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2013-01-30 Classification: LIGASE/LIGASE INHIBITOR Ligands: ZN, 1AQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-01-30
Ligands: ZN, 1AQ
 |
Gsk3Beta Inhibitor Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2010-03-02 Classification: TRANSFERASE Ligands: G3B |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-03-02
Ligands: G3B
 |
X-Ray Co-Crystal Structure Of Glycogen Synthase Kinase 3Beta In Complex With An Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2009-03-10 Classification: TRANSFERASE Ligands: 34O |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-03-10
Ligands: 34O
 |
Glycogen Synthase Kinase 3Beta Inhibitor Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2009-03-10 Classification: TRANSFERASE Ligands: 3HT, 2HT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-03-10
Ligands: 3HT, 2HT
 |
Crystal Structure Of Human Fibroblast Activation Protein Alpha
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2005-04-12 Classification: LYASE Ligands: NAG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2005-04-12
Ligands: NAG
 |
Crystal Structure Of The Interface Open Conformation Of Tetrameric 11B-Hsd1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2004-11-02 Classification: OXIDOREDUCTASE Ligands: NDP, CPS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2004-11-02
Ligands: NDP, CPS
 |
Crystal Structure Of The Interface Closed Conformation Of 11B-Hydroxysteroid Dehydrogenase Isozyme 1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2004-11-02 Classification: OXIDOREDUCTASE Ligands: NDP, CPS, MES |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2004-11-02
Ligands: NDP, CPS, MES
 |
Structural Basis For The Autoinhibition And Sti-571 Inhibition Of C-Kit Tyrosine Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2004-06-15 Classification: TRANSFERASE ACTIVATOR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2004-06-15