Search Count: 16
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Crystal Structure Of Flt3 With A Small Molecule Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.10 Å Release Date: 2015-04-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: P30 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-04-22
Ligands: P30
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The Crystal Structure Of Human Nicotinamide Phosphoribosyltransferase (Nampt) In Complex With N-(4-{(S)-[1-(2-Methylpropyl)Piperidin-4-Yl]Sulfinyl}Benzyl)Furo[2,3-C]Pyridine-2-Carboxamide Inhibitor (Compound 21)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.72 Å Release Date: 2015-02-11 Classification: Transferase/Transferase inhibitor Ligands: 3TQ, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-02-11
Ligands: 3TQ, PO4, EDO
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Discovery Of Potent And Efficacious Cyanoguanidine-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.69 Å Release Date: 2013-12-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: LTS, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-12-25
Ligands: LTS, PO4, EDO
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Discovery Of Potent And Efficacious Cyanoguanidine-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.64 Å Release Date: 2013-12-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: LWW, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-12-25
Ligands: LWW, PO4, EDO
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Fragment-Based Identification Of Amides Derived From Trans-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.81 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 20J, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: 20J, PO4, EDO
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Fragment-Based Identification Of Amides Derived From Trans-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 20M, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: 20M, PO4, EDO
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Fragment-Based Identification Of Amides Derived From Trans-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 20N, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: 20N, PO4, EDO
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Fragment-Based Identification Of Amides Derived From Trans-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: PO4, 1EB, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: PO4, 1EB, EDO
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Fragment-Based Identification Of Amides Derived From Trans-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 20P, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: 20P, PO4, EDO
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Fragment-Based Identification Of Amides Derived From Trans-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 20O, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: 20O, PO4, EDO
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Identification Of Amides Derived From 1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 20R, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: 20R, PO4
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Identification Of Amides Derived From 1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid As Potent Inhibitors Of Human Nicotinamide Phosphoribosyltransferase (Nampt)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.41 Å Release Date: 2013-09-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 20T, POP, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-25
Ligands: 20T, POP, PO4
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Discovery Of Potent And Efficacious Urea-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors With Reduced Cyp2C9 Inhibition Properties
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2013-05-29 Classification: Transferase/Transferase inhibitor Ligands: 1LJ, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: 1LJ, PO4, EDO
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Structure-Based Identification Of Ureas As Novel Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.91 Å Release Date: 2013-05-08 Classification: Transferase/Transferase inhibitor Ligands: 1LS, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-08
Ligands: 1LS, PO4, EDO
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Structure-Based Discovery Of Novel Amide-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2013-05-08 Classification: Transferase/Transferase Inhibitor Ligands: 1QR, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-08
Ligands: 1QR, PO4, EDO
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Structure-Based Discovery Of Novel Amide-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2013-05-08 Classification: Transferase/transferase Inhibitor Ligands: 1QS, PO4, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-08
Ligands: 1QS, PO4, EDO