Search Count: 12
 |
Jak2 Kinase (Jh1 Domain) In Complex With The Inhibitor Trans-4-[(8As)-2-[(1R)-1-Hydroxyethyl]Imidazo[4,5-D]Pyrrolo[2,3-B]Pyridin-1(8Ah)-Yl]Cyclohexanecarbonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1J5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 1J5
 |
Jak1 Kinase (Jh1 Domain) In Complex With The Inhibitor Trans-4-{2-[(1R)-1-Hydroxyethyl]Imidazo[4,5-D]Pyrrolo[2,3-B]Pyridin-1(6H)-Yl}Cyclohexanecarbonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1J5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 1J5
 |
Jak1 Kinase (Jh1 Domain) In Complex With The Inhibitor (Trans-4-{2-[(1R)-1-Hydroxyethyl]Imidazo[4,5-D]Pyrrolo[2,3-B]Pyridin-1(6H)-Yl}Cyclohexyl)Acetonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1J6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 1J6
 |
Jak1 Kinase (Jh1 Domain) In Complex With Compound 34
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 15T |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 15T
 |
The Jak1 Kinase Domain In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2012-07-04 Classification: Transferase/Transferase Inhibitor Ligands: JAK, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-07-04
Ligands: JAK, EDO
 |
Jak1 Kinase (Jh1 Domain) In Complex With Compound 20
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.22 Å Release Date: 2012-07-04 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0Q2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-07-04
Ligands: 0Q2
 |
Discovery And Optimization Of C-2 Methyl Imidazo-Pyrrolopyridines As Potent And Orally Bioavailable Jak1 Inhibitors With Selectivity Over Jak2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.82 Å Release Date: 2012-07-04 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1RS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-07-04
Ligands: 1RS
 |
Discovery And Optimization Of C-2 Methyl Imidazo-Pyrrolopyridines As Potent And Orally Bioavailable Jak1 Inhibitors With Selectivity Over Jak2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2012-07-04 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: JAK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-07-04
Ligands: JAK
 |
Human B-Raf Kinase Domain In Complex With An Bromopyridine Benzamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.40 Å Release Date: 2011-10-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: TV4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-10-05
Ligands: TV4
 |
Human B-Raf Kinase Domain In Complex With A Methoxypyrazolopyridinyl Benzamide Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.30 Å Release Date: 2011-10-05 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: B0R |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-10-05
Ligands: B0R
 |
A Transforming Mutation In The Pleckstrin Homology Domain Of Akt1 In Cancer (Akt1-Ph_E17K)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2007-07-17 Classification: TRANSFERASE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-07-17
 |
A Transforming Mutation In The Pleckstrin Homology Domain Of Akt1 In Cancer (Akt1-Ph_E17K)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.46 Å Release Date: 2007-07-17 Classification: TRANSFERASE Ligands: 4IP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2007-07-17
Ligands: 4IP