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Search Count: 18

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9CSK image
Crystal Structure Of Cdk4 Cyclin D1 In Complex With Atirmociclib

9D8U image
Crystal Structure Of Cdk6 In Complex With Atirmociclib

5KZ0 image
Structure Of Human Anaplastic Lymphoma Kinase In Complex With 2-[(1R)-1-{[2-Amino-5-(1,3-Dimethyl-1H-Pyrazol-4-Yl)Pyridin-3-Yl]Oxy}Ethyl]-4-Fluoro-N,N-Dimethylbenzamide

4CLI image
Structure Of The Human Anaplastic Lymphoma Kinase In Complex With Pf- 06463922 ((10R)-7-Amino-12-Fluoro-2,10,16-Trimethyl-15-Oxo-10,15,16, 17-Tetrahydro-2H-8,4-(Metheno)Pyrazolo(4,3-H)(2,5,11) Benzoxadiazacyclotetradecine-3-Carbonitrile).
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.05 Å Release Date: 2014-05-28
Classification: TRANSFERASE
Ligands: 5P8

4CLJ image
Structure Of L1196M Mutant Human Anaplastic Lymphoma Kinase In Complex With Pf-06463922 ((10R)-7-Amino-12-Fluoro-2,10,16-Trimethyl- 15-Oxo-10,15,16,17-Tetrahydro-2H-8,4-(Metheno)Pyrazolo(4,3-H)(2,5,11) Benzoxadiazacyclotetradecine-3-Carbonitrile).
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.66 Å Release Date: 2014-05-28
Classification: TRANSFERASE
Ligands: 5P8

4CMO image
Structure Of The Human Anaplastic Lymphoma Kinase In Complex With The Inhibitor 2-((1R)-1-((3-Amino-6-(2-Methoxypyridin-3-Yl)Pyrazin-2-Yl) Oxy)Ethyl)-4-Fluoro-N-Methylbenzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.05 Å Release Date: 2014-05-28
Classification: TRANSFERASE
Ligands: YPW

4CMT image
Structure Of The Human Anaplastic Lymphoma Kinase In Complex With The Inhibitor 3-((1R)-1-(5-Fluoro-2-(2H-1,2,3-Triazol-2-Yl)Phenyl)Ethoxy)- 5-(3-(Methylsulfonyl)Phenyl)Pyridin-2-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.73 Å Release Date: 2014-05-28
Classification: TRANSFERASE
Ligands: GWH

4CMU image
Structure Of The Human Anaplastic Lymphoma Kinase In Complex With The Inhibitor (10R)-7-Amino-12-Fluoro-1,3,10,16-Tetramethyl-16,17-Dihydro- 1H-8,4-(Metheno)Pyrazolo(4,3-H)(2,5,11)Benzoxadiazacyclotetradecin-15(10H)-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.80 Å Release Date: 2014-05-28
Classification: TRANSFERASE
Ligands: IV7

4CNH image
Structure Of The Human Anaplastic Lymphoma Kinase In Complex With The Inhibitor 3-((1R)-1-(5-Fluoro-2-Methoxyphenyl)Ethoxy)-5-(1-Methyl-1H- 1,2,3-Triazol-5-Yl)Pyridin-2-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.90 Å Release Date: 2014-05-28
Classification: TRANSFERASE
Ligands: 3U9

4CTB image
Structure Of The Human Anaplastic Lymphoma Kinase In Complex With The Inhibitor (5R)-8-Amino-3-Fluoro-5,19-Dimethyl-20-Oxo-5,18,19,20- Tetrahydro-7,11-(Azeno)Pyrido(2',1':2,3)Imidazo(4,5-H)(2,5,11) Benzoxadiazacyclotetradecine-14-Carbonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.79 Å Release Date: 2014-05-28
Classification: TRANSFERASE
Ligands: KVC

4CTC image
Structure Of The Human Anaplastic Lymphoma Kinase In Complex With The Inhibitor 7-Amino-3-Cyclopropyl-12-Fluoro-1,10,16-Trimethyl-16,17- Dihydro-1H-8,4-(Metheno)Pyrazolo(4,3-H)(2,5,11) Benzoxadiazacyclotetradecin-15(10H)-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.03 Å Release Date: 2014-05-28
Classification: TRANSFERASE
Ligands: J99

4CCB image
Structure Of The Human Anaplastic Lymphoma Kinase In Complex With 3-((R)-1-(5-Fluoro-2-(2H-1,2,3-Triazol-2-Yl)Phenyl)Ethoxy)-5-(5-Methyl-1H- Pyrazol-4-Yl)Pyridin-2-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.03 Å Release Date: 2014-01-29
Classification: TRANSFERASE
Ligands: OFG

4CCU image
Structure Of The Human Anaplastic Lymphoma Kinase In Complex With 2-(5-(6-Amino-5-((R)-1-(5-Fluoro-2-(2H-1,2,3-Triazol-2-Yl)Phenyl)Ethoxy) Pyridin-3-Yl)-4-Methylthiazol-2-Yl)Propan-2-Ol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.00 Å Release Date: 2014-01-29
Classification: TRANSFERASE
Ligands: AWF

4CD0 image
Structure Of L1196M Mutant Human Anaplastic Lymphoma Kinase In Complex With 2-(5-(6-Amino-5-((R)-1-(5-Fluoro-2-(2H-1,2,3-Triazol-2- Yl)Phenyl)Ethoxy)Pyridin-3-Yl)-4-Methylthiazol-2-Yl)Propane-1,2-Diol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.23 Å Release Date: 2014-01-29
Classification: TRANSFERASE
Ligands: AWJ

4ANL image
Structure Of G1269A Mutant Anaplastic Lymphoma Kinase

4ANQ image
Structure Of G1269A Mutant Anaplastic Lymphoma Kinase In Complex With Crizotinib
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.76 Å Release Date: 2013-03-27
Classification: TRANSFERASE
Ligands: VGH

2YHV image
Structure Of L1196M Mutant Anaplastic Lymphoma Kinase

2YFX image
Structure Of L1196M Mutant Anaplastic Lymphoma Kinase In Complex With Crizotinib
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.70 Å Release Date: 2011-05-04
Classification: TRANSFERASE
Ligands: VGH
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