Search Count: 12
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From Dna-Encoded Library Screening To Am-9747 - An Mta-Cooperative Prmt5 Inhibitor With Potent Oral In Vivo Efficacy
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2025-03-26 Classification: TRANSFERASE/INHIBITOR Ligands: A1BQW, MTA, GOL, PEG, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-03-26
Ligands: A1BQW, MTA, GOL, PEG, DMS
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Structure Of The Kdm1A/Corest Complex With The Inhibitor 2-[3-{4-Chloro-3-[(4-Chlorophenyl)Ethynyl]Phenyl}-1-(3-Morpholin-4-Ylpropyl)-1,4,6,7-Tetrahydro-5H-Pyrazolo[4,3-C]Pyridin-5-Yl]-2-Oxoethanol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.11 Å Release Date: 2020-06-03 Classification: OXIDOREDUCTASE Ligands: N4K, FAD, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-06-03
Ligands: N4K, FAD, GOL
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Thieno[3,2-B]Pyrrole-5-Carboxamides As Novel Reversible Inhibitors Of Histone Lysine Demethylase Kdm1A/Lsd1: Compound 19
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.20 Å Release Date: 2017-02-22 Classification: OXIDOREDUCTASE Ligands: FAD, 6W0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: FAD, 6W0
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Thieno[3,2-B]Pyrrole-5-Carboxamides As Novel Reversible Inhibitors Of Histone Lysine Demethylase Kdm1A/Lsd1: Compound 15
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2017-02-22 Classification: OXIDOREDUCTASE Ligands: FAD, 6W3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: FAD, 6W3
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Thieno[3,2-B]Pyrrole-5-Carboxamides As Novel Reversible Inhibitors Of Histone Lysine Demethylase Kdm1A/Lsd1: Compound 34
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.20 Å Release Date: 2017-02-22 Classification: OXIDOREDUCTASE Ligands: FAD, 6W1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: FAD, 6W1
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Structure Of The Kdm1A/Corest Complex With The Inhibitor 4-Methyl-N-[4-[[4-(1-Methylpiperidin-4-Yl)Oxyphenoxy]Methyl]Phenyl]Thieno[3,2-B]Pyrrole-5-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.34 Å Release Date: 2017-02-22 Classification: OXIDOREDUCTASE Ligands: FAD, GOL, 6X3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: FAD, GOL, 6X3
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Structure Of The Kdm1A/Corest Complex With The Inhibitor 4-Ethyl-N-[3-(Methoxymethyl)-2-[[4-[[(3R)-Pyrrolidin-3-Yl]Methoxy]Phenoxy]Methyl]Phenyl]Thieno[3,2-B]Pyrrole-5-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.05 Å Release Date: 2017-02-22 Classification: OXIDOREDUCTASE Ligands: FAD, GOL, 6X0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: FAD, GOL, 6X0
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Structure Of The Kdm1A/Corest Complex With The Inhibitor N-[3-(Ethoxymethyl)-2-[[4-[[(3R)-Pyrrolidin-3-Yl]Methoxy]Phenoxy]Methyl]Phenyl]-4-Methylthieno[3,2-B]Pyrrole-5-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.40 Å Release Date: 2017-02-22 Classification: OXIDOREDUCTASE Ligands: FAD, 6X5, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-02-22
Ligands: FAD, 6X5, GOL
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Crystal Structure Of The L317I Mutant Of The C-Src Tyrosine Kinase Domain Complexed With Pyrazolopyrimidine 5
Organism: Gallus gallus
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2012-02-08 Classification: TRANSFERASE Ligands: PD5 |
Organism: Gallus gallus
Method: X-RAY DIFFRACTION
Release Date: 2012-02-08
Ligands: PD5
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Crystal Structure Of The L317I Mutant Of The C-Src Tyrosine Kinase Domain Complexed With Dasatinib
Organism: Gallus gallus
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2012-02-08 Classification: TRANSFERASE Ligands: 1N1 |
Organism: Gallus gallus
Method: X-RAY DIFFRACTION
Release Date: 2012-02-08
Ligands: 1N1
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Crystal Structure Of The L317I Mutant Of The Chicken C-Src Tyrosine Kinase Domain Complexed With Imatinib
Organism: Gallus gallus
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2011-08-17 Classification: TRANSFERASE Ligands: STI, ACT, GOL |
Organism: Gallus gallus
Method: X-RAY DIFFRACTION
Release Date: 2011-08-17
Ligands: STI, ACT, GOL
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Crystal Structure Of The L317I Mutant Of The Chicken C-Src Tyrosine Kinase Domain
Organism: Gallus gallus
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2011-08-17 Classification: TRANSFERASE |
Organism: Gallus gallus
Method: X-RAY DIFFRACTION
Release Date: 2011-08-17