Search Count: 17
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Bace1 In Complex With (S)-5-(3-Chloro-5-(5-(Prop-1-Yn-1-Yl)Pyridin-3-Yl)Thiophen-2-Yl)-2,5-Dimethyl-1,2,4-Thiadiazinan-3-Iminium 1,1-Dioxide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2016-11-09 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 66J |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-09
Ligands: 66J
 |
Bace1 In Complex With 4-(3-(Furan-2-Carboxamido)Phenyl)-1-Methyl-5-Oxo-4-Phenylimidazolidin-2-Iminium
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.83 Å Release Date: 2016-11-09 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: TLA, 66H |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-09
Ligands: TLA, 66H
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Bace1 In Complex With (R)-N-(3-(3-Amino-2,5-Dimethyl-1,1-Dioxido-5,6-Dihydro-2H-1,2,4-Thiadiazin-5-Yl)-4-Fluorophenyl)-5-Fluoropicolinamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2016-11-09 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 66F |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-09
Ligands: 66F
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Bace-1 In Complex With (7Ar)-7A-(4-(3-Cyanophenyl)Thiophen-2-Yl)-6-(5-Fluoropyrimidin-2-Yl)-3-Methyl-4-Oxooctahydro-2H-Pyrrolo[3,4-D]Pyrimidin-2-Iminium
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.65 Å Release Date: 2016-03-16 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: TLA, 60Y |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-03-16
Ligands: TLA, 60Y
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Bace-1 Incomplex With (7Ar)-7A-(4-(3-Cyanophenyl)Thiophen-2-Yl)-6-(5-Fluoro-4-Methoxypyrimidin-2-Yl)-3-Methyl-4-Oxooctahydro-2H-Pyrrolo[3,4-D]Pyrimidin-2-Iminium
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.58 Å Release Date: 2016-03-16 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: TLA, 60W |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-03-16
Ligands: TLA, 60W
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Bace-1 Incomplex With (7Ar)-7A-(5-Cyanothiophen-2-Yl)-6-(5-Fluoro-4-Methoxy-6-Methylpyrimidin-2-Yl)-3-Methyl-4-Oxooctahydro-2H-Pyrrolo[3,4-D]Pyrimidin-2-Iminium
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.71 Å Release Date: 2016-03-16 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 60V, TLA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-03-16
Ligands: 60V, TLA
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Bace-1 In Complex With (7Ar)-7A-(5-Cyanothiophen-2-Yl)-6-(4-Ethoxy-5-Fluoro-6-Methylpyrimidin-2-Yl)-3-Methyl-4-Oxooctahydro-2H-Pyrrolo[3,4-D]Pyrimidin-2-Iminium
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2016-03-16 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 60U |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-03-16
Ligands: 60U
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Bace-1 In Complex With (7Ar)-7A-(5-Cyanothiophen-2-Yl)-6-(5-Fluoro-4-Methyl-6-(Methylthio)Pyrimidin-2-Yl)-3-Methyl-4-Oxooctahydro-2H-Pyrrolo[3,4-D]Pyrimidin-2-Iminium
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.49 Å Release Date: 2016-03-16 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 954 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-03-16
Ligands: 954
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Bace-1 In Complex With (4Ar,7As)-7A-(2,6-Difluorophenyl)-6-(5-Fluoro-4-Methoxy-6-Methylpyrimidin-2-Yl)-3-Methyl-4-Oxooctahydro-2H-Pyrrolo[3,4-D]Pyrimidin-2-Iminium
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.53 Å Release Date: 2016-03-16 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 60T, TLA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-03-16
Ligands: 60T, TLA
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Bace-1 In Complex With (7Ar)-7A-(5-Cyanothiophen-2-Yl)-6-(5-Fluoro-4-Methyl-6-(Methylamino)Pyrimidin-2-Yl)-3-Methyl-4-Oxooctahydro-2H-Pyrrolo[3,4-D]Pyrimidin-2-Iminium
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2016-03-16 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: TLA, 60S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-03-16
Ligands: TLA, 60S
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Bace-1 In Complex With (4Ar,7As)-7A-(2,4-Difluorophenyl)-6-(5-Fluoro-4-Methoxy-6-Methylpyrimidin-2-Yl)-2-Imino-3-Methyloctahydro-4H-Pyrrolo[3,4-D]Pyrimidin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.71 Å Release Date: 2016-03-16 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 60X |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-03-16
Ligands: 60X
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Structure Of Bace In Complex With (S)-4-(3-Chloro-5-(5-(Prop-1-Yn-1-Yl)Pyridin-3-Yl)Thiophen-2-Yl)-1,4-Dimethyl-6-Oxotetrahydropyrimidin-2(1H)-Iminium
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2012-08-08 Classification: Hydrolase/Hydrolase inhibitor Ligands: 0V6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-08-08
Ligands: 0V6
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Structure Of Bace Bound To 2-Imino-3-Methyl-5,5-Diphenylimidazolidin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2012-03-21 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 0KK, TLA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-03-21
Ligands: 0KK, TLA
 |
Structure Of Bace Bound To 2-Imino-5-(3'-Methoxy-[1,1'-Biphenyl]-3-Yl)-3-Methyl-5-Phenylimidazolidin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.73 Å Release Date: 2012-03-21 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 0KM, TLA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-03-21
Ligands: 0KM, TLA
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Structure Of Bace Bound To 2-Imino-3-Methyl-5-Phenyl-5-(3-(Pyridin-3-Yl)Phenyl)Imidazolidin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2012-03-21 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 0KP, TLA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-03-21
Ligands: 0KP, TLA
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Structure Of Bace Bound To 5-(3-(5-Chloropyridin-3-Yl)Phenyl)-5-Cyclopropyl-2-Imino-3-Methylimidazolidin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2012-03-21 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 0KQ, TLA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-03-21
Ligands: 0KQ, TLA
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Structure Of Bace Bound To (R)-5-Cyclopropyl-2-Imino-3-Methyl-5-(3-(5-(Prop-1-Yn-1-Yl)Pyridin-3-Yl)Phenyl)Imidazolidin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.86 Å Release Date: 2012-03-21 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 0KR, TLA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-03-21
Ligands: 0KR, TLA