Search Count: 28
 |
Discovery Of A Small Molecule Itk And Pan-Trk Kinase Inhibitor (Pf-07245303) For The Potential Topical Treatment Of Atopic Dermatitis
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.35 Å Release Date: 2025-11-19 Classification: SIGNALING PROTEIN Ligands: A1B66 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-11-19
Ligands: A1B66
 |
Pad2 With An Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.18 Å Release Date: 2025-07-30 Classification: HYDROLASE Ligands: A1CE0, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-07-30
Ligands: A1CE0, CA
 |
Potent Inhibition Of The Protein Arginine Deiminases (Pad1-4) By Targeting A Ca2+ Dependent Allosteric Binding Site
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.77 Å Release Date: 2025-05-28 Classification: HYDROLASE Ligands: CA, A1A8O |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-28
Ligands: CA, A1A8O
 |
Inhibiting Peptidylarginine Deiminases (Pad1-4) By Targeting A Ca2+ Dependent Allosteric Binding Site
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.44 Å Release Date: 2025-05-28 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: CA, A1BZK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-28
Ligands: CA, A1BZK
 |
Potent Inhibition Of The Protein Arginine Deiminases (Pad1-4) By Targeting A Ca2+ Dependent Allosteric Binding Site
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.41 Å Release Date: 2025-05-28 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: A1A9P, 3YZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-28
Ligands: A1A9P, 3YZ
 |
Vanin-1 Complexed With Compound 3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.13 Å Release Date: 2022-01-12 Classification: HYDROLASE Ligands: NAG, 9TC, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-12
Ligands: NAG, 9TC, NA
 |
Vanin-1 Complexed With Compound 11
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2022-01-12 Classification: HYDROLASE Ligands: NAG, 9SS, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-12
Ligands: NAG, 9SS, NA
 |
Vanin-1 Complexed With Compound 27
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.17 Å Release Date: 2022-01-12 Classification: HYDROLASE Ligands: NAG, 9S5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-12
Ligands: NAG, 9S5
 |
Discovery Of A High Affinity Inhibitor Of Cgas
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.23 Å Release Date: 2018-12-19 Classification: transferase/transferase inhibitor Ligands: ZN, KHM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-12-19
Ligands: ZN, KHM
 |
Crystal Structure Of Ask1 Kinase Domain With A Potent Inhibitor (Analog 6)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.64 Å Release Date: 2018-01-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 9E1, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-01-17
Ligands: 9E1, DMS
 |
Crystal Structure Of Ask1 Kinase Domain With A Potent Inhibitor (Analog 13)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.84 Å Release Date: 2018-01-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 9E4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-01-17
Ligands: 9E4
 |
Discovery Of A High Affinity Inhibitor Of Cgas
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.10 Å Release Date: 2017-09-27 Classification: transferase/transferase inhibitor Ligands: ZN, 8ZM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-27
Ligands: ZN, 8ZM
 |
Crystal Structure Of Irak4 In Complex With Compound 9
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.64 Å Release Date: 2017-05-24 Classification: TRANSFERASE Ligands: 8BV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-24
Ligands: 8BV
 |
Crystal Structure Of Irak4 In Complex With Compound 11
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.64 Å Release Date: 2017-05-24 Classification: TRANSFERASE Ligands: 8BY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-24
Ligands: 8BY
 |
Crystal Structure Of Irak4 In Complex With Compound 12
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2017-05-24 Classification: TRANSFERASE Ligands: 8C1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-24
Ligands: 8C1
 |
Crystal Structure Of Irak4 In Complex With Compound 14
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2017-05-24 Classification: TRANSFERASE Ligands: 8CD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-24
Ligands: 8CD
 |
Crystal Structure Of Irak4 In Complex With Compound 30
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.02 Å Release Date: 2017-05-24 Classification: TRANSFERASE Ligands: 8CG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-24
Ligands: 8CG
 |
Crystal Structure Of Syk In Complex With Compound 1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2015-10-07 Classification: TRANSFERASE/INHIBITOR Ligands: 50H |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-10-07
Ligands: 50H
 |
Crystal Structure Of Syk In Complex With Compound 2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2015-10-07 Classification: TRANSFERASE/INHIBITOR Ligands: 50J, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-10-07
Ligands: 50J, GOL
 |
Crystal Structure Of Syk Kinase Domain With 1-(5-(6,7-Dimethoxyquinolin-4-Yloxy)Pyridin-2-Yl)-3-((1R,2S)-2-Phenylcyclopropyl)Urea
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.23 Å Release Date: 2012-08-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: FPU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-08-29
Ligands: FPU