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Structure Of Chk1 10-Pt. Mutant Complex With Macrocyclic Lrrk2 Inhibitor Compound 1 ((11R)-8-Chloro-3,11-Dimethyl-2-(Oxan-4-Yl)-2,4,10,11,12,13-Hexahydro-9,5-(Azeno)Pyrazolo[3,4-B][1,4,6,10]Oxatriazacyclotridecine)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.03 Å Release Date: 2026-04-08 Classification: TRANSFERASE/INHIBITOR Ligands: A1C5F |
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Structure Of Chk1 10-Pt. Mutant Complex With Macrocyclic Lrrk2 Inhibitor Compound 7 ((10As,13As)-3-Cyclobutyl-1-Methyl-8-(Trifluoromethyl)-3,4,10A,11,13A,14-Hexahydro-10H,13H-9,5-(Azeno)Furo[3,4-K]Pyrazolo[4,3-B][1,4,6,10]Oxatriazacyclotridecine)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.67 Å Release Date: 2026-04-08 Classification: TRANSFERASE/INHIBITOR Ligands: A1C5G |
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Structure Of Chk1 10-Pt. Mutant Complex With Macrocyclic Lrrk2 Inhibitor Compound 12 ((10As,13As)-3-Cyclopropyl-1-Methyl-8-(Trifluoromethyl)-3,4,10A,11,13A,14-Hexahydro-10H,13H-9,5-(Azeno)Furo[3,4-K]Pyrazolo[4,3-B][1,4,6,10]Oxatriazacyclotridecine)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.74 Å Release Date: 2026-04-08 Classification: TRANSFERASE/INHIBITOR Ligands: A1C5H |
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Organism: Spodoptera frugiperda
Method: X-RAY DIFFRACTION Resolution:2.34 Å Release Date: 2025-09-10 Classification: HYDROLASE Ligands: ZN, A1CEV |
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Organism: Spodoptera frugiperda
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2025-09-10 Classification: HYDROLASE Ligands: ZN, A1CEW, CL, EDO |
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Organism: Spodoptera frugiperda
Method: X-RAY DIFFRACTION Resolution:1.56 Å Release Date: 2025-09-10 Classification: HYDROLASE Ligands: ZN, A1CEX, EDO, CL |
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Organism: Spodoptera frugiperda
Method: X-RAY DIFFRACTION Resolution:1.67 Å Release Date: 2025-09-10 Classification: HYDROLASE Ligands: ZN, A1CEY, EDO, DMS |
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Organism: Spodoptera frugiperda
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2025-09-10 Classification: HYDROLASE Ligands: ZN, A1CEZ, EDO, DMS |
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Structure Of Chk1 10-Pt. Mutant Complex With Lrrk2 Indazole Inhibitor Compound 6
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.31 Å Release Date: 2024-09-18 Classification: TRANSFERASE Ligands: A1AV4, EDO |