Search Count: 18
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P110Alpha/P85Alpha With Compound 5
Organism: Homo sapiens, Bos taurus
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2016-01-27 Classification: Transferase/Transferase Inhibitor Ligands: 5H2 |
Organism: Homo sapiens, Bos taurus
Method: X-RAY DIFFRACTION
Release Date: 2016-01-27
Ligands: 5H2
 |
P110Alpha With Gdc-0326
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2016-01-27 Classification: Transferase/Inhibitor Ligands: 5H5, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-01-27
Ligands: 5H5, EDO
 |
P110Delta/P85Alpha With Gdc-0326
Organism: Homo sapiens, Bos taurus
Method: X-RAY DIFFRACTION Resolution:2.64 Å Release Date: 2016-01-27 Classification: Transferase/Inhibitor Ligands: 5H5 |
Organism: Homo sapiens, Bos taurus
Method: X-RAY DIFFRACTION
Release Date: 2016-01-27
Ligands: 5H5
 |
Discovery Of Thiazolobenzoxepin Pi3-Kinase Inhibitors That Spare The Pi3-Kinase Beta Isoform
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2013-08-28 Classification: Transferase/Transferase Inhibitor Ligands: 1JV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-08-28
Ligands: 1JV
 |
Potent And Selective Inhibitors Of Pi3K-Delta: Obtaining Isoform Selectivity From The Affinity Pocket And Tryptophan Shelf
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.67 Å Release Date: 2013-04-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0SC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-17
Ligands: 0SC
 |
Potent And Selective Inhibitors Of Pi3K-Delta: Obtaining Isoform Selectivity From The Affinity Pocket And Tryptophan Shelf
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2013-04-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0SD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-17
Ligands: 0SD
 |
Potent And Selective Inhibitors Of Pi3K-Delta: Obtaining Isoform Selectivity From The Affinity Pocket And Tryptophan Shelf
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.94 Å Release Date: 2013-04-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0SE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-17
Ligands: 0SE
 |
Compound 21 (1-Alkyl-Substituted 1,2,4-Triazoles)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.78 Å Release Date: 2013-01-09 Classification: Transferase/Transferase Inhibitor Ligands: 17V |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-01-09
Ligands: 17V
 |
Potent And Highly Selective Benzimidazole Inhibitors Of Pi3K-Delta
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.44 Å Release Date: 2012-08-22 Classification: transferase/transferase inhibitor Ligands: 0WR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-08-22
Ligands: 0WR
 |
Rational Design Of Pi3K-Alpha Inhibitors That Exhibit Selectivity Over The Pi3K-Beta Isoform
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2011-11-16 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3T8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-11-16
Ligands: 3T8
 |
Discovery Of Gdc-0980: A Potent, Selective, And Orally Available Class I Phosphatidylinositol 3-Kinase (Pi3K)/Mammalian Target Of Rapamycin (Mtor) Kinase Inhibitor For The Treatment Of Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.79 Å Release Date: 2011-11-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 980 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-11-02
Ligands: 980
 |
Structure-Based Design Of Thienobenzoxepin Inhibitors Of Pi3- Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2011-08-03 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: FAV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-08-03
Ligands: FAV
 |
Structure-Based Design Of Thienobenzoxepin Inhibitors Of Pi3-Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2011-08-03 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: FAZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-08-03
Ligands: FAZ
 |
Structure-Based Optimization Of Pyrazolo -Pyrimidine And -Pyridine Inhibitors Of Pi3-Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2010-12-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: NZS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-12-29
Ligands: NZS
 |
Structure-Based Optimization Of Pyrazolo -Pyrimidine And -Pyridine Inhibitors Of Pi3-Kinase
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2010-12-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: NZU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-12-29
Ligands: NZU
 |
Crystal Structures Of Pan-Pi3-Kinase And Dual Pan-Pi3-Kinase/Mtor Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2010-02-16 Classification: TRANSFERASE Ligands: JZW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-02-16
Ligands: JZW
 |
Discovery Of (Thienopyrimidin-2-Yl)Aminopyrimidines As Potent, Selective, And Orally Available Pan-Pi3-Kinase And Dual Pan-Pi3-Kinase/Mtor Inhibitors For The Treatment Of Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2010-02-16 Classification: TRANSFERASE Ligands: JZX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-02-16
Ligands: JZX
 |
Discovery Of (Thienopyrimidin-2-Yl)Aminopyrimidines As Potent, Selective, And Orally Available Pan-Pi3-Kinase And Dual Pan-Pi3-Kinase/Mtor Inhibitors For The Treatment Of Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2010-02-16 Classification: TRANSFERASE Ligands: JZY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-02-16
Ligands: JZY