Search Count: 21
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.39 Å Release Date: 2022-11-23 Classification: HYDROLASE Ligands: ZN, 8IY |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2022-11-02 Classification: HYDROLASE Ligands: ZN, 98O |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2022-11-02 Classification: HYDROLASE Ligands: ZN, 99I |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:1.92 Å Release Date: 2022-11-02 Classification: HYDROLASE Ligands: ZN, 9DO |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2022-11-02 Classification: HYDROLASE Ligands: ZN, 9A1 |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.01 Å Release Date: 2022-11-02 Classification: HYDROLASE Ligands: ZN, 9B9 |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Escherichia coli (strain k12)
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2022-09-07 Classification: HYDROLASE Ligands: ZN, 7PX |
Organism: Escherichia coli (strain k12)
Method: X-RAY DIFFRACTION
Release Date: 2022-09-07
Ligands: ZN, 7PX
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2022-09-07 Classification: HYDROLASE Ligands: ZN, 7PX |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2022-09-07 Classification: HYDROLASE Ligands: ZN, 7S6 |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.04 Å Release Date: 2022-09-07 Classification: HYDROLASE Ligands: ZN, 7S2 |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2022-09-07 Classification: HYDROLASE Ligands: ZN, 7T5, EDO |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.55 Å Release Date: 2022-09-07 Classification: HYDROLASE Ligands: ZN, 7TF |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2022-09-07 Classification: HYDROLASE Ligands: ZN, 6G8 |
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[1,2,4]Triazolo[1,5-A]Pyrimidine Phosphodiesterase 2 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.88 Å Release Date: 2020-11-04 Classification: HYDROLASE Ligands: ZN, MG, QOQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-11-04
Ligands: ZN, MG, QOQ
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[1,2,4]Triazolo[1,5-A]Pyrimidine Phosphodiesterase 2 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2020-07-22 Classification: HYDROLASE Ligands: ZN, MG, QMZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-07-22
Ligands: ZN, MG, QMZ
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Multi-Parameter Lead Optimization To Give An Oral Chk1 Inhibitor Clinical Candidate: (R)-5-((4-((Morpholin-2-Ylmethyl)Amino)-5-(Trifluoromethyl)Pyridin-2-Yl)Amino)Pyrazine-2-Carbonitrile (Cct245737)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.91 Å Release Date: 2016-05-25 Classification: TRANSFERASE Ligands: 5UY, EDO, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-05-25
Ligands: 5UY, EDO, GOL
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Crystal Structure Of Active Caspase-6 In Complex With Ac-Veid-Cho Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2011-09-28 Classification: HYDROLASE/HYDROLASE INHIBITOR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-09-28
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Caspase-6 In Complex With Z-Vad-Fmk Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2011-09-21 Classification: HYDROLASE/HYDROLASE INHIBITOR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-09-21
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Crystal Structure Of Apo-Caspase-6 At Physiological Ph
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.53 Å Release Date: 2011-06-15 Classification: HYDROLASE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-06-15
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Crystal Structure Of Cys25Ser Mutant Of Human Cathepsin S
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2002-08-29 Classification: HYDROLASE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2002-08-29