Search Count: 8
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Discovery Of Mta-Cooperative Prmt5 Inhibitors From Co-Factor Directed Dna-Encoded Library Screens
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.10 Å Release Date: 2025-05-07 Classification: TRANSFERASE/INHIBITOR Ligands: A1B6Y, MTA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-07
Ligands: A1B6Y, MTA
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From Dna-Encoded Library Screening To Am-9747 - An Mta-Cooperative Prmt5 Inhibitor With Potent Oral In Vivo Efficacy
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2025-03-26 Classification: TRANSFERASE/INHIBITOR Ligands: A1BQW, MTA, GOL, PEG, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-03-26
Ligands: A1BQW, MTA, GOL, PEG, DMS
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Amg 193, A Clinical Stage Mta-Cooperative Prmt5 Inhibitor, Drives Anti-Tumor Activity Preclinically And In Patients With Mtap-Deleted Cancers
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.85 Å Release Date: 2024-10-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: GOL, DMS, A1ATH, MTA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-02
Ligands: GOL, DMS, A1ATH, MTA
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Structure Of Caenorhabditis Elegans Cisd-1/Mitoneet
Organism: Caenorhabditis elegans
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2022-10-19 Classification: METAL BINDING PROTEIN Ligands: FES |
Organism: Caenorhabditis elegans
Method: X-RAY DIFFRACTION
Release Date: 2022-10-19
Ligands: FES
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Structure Of Human Mthfd2 In Complex With Th9028
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2021-07-07 Classification: OXIDOREDUCTASE Ligands: KUK, PO4, NAD, MPD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-07-07
Ligands: KUK, PO4, NAD, MPD
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Structure Of Human Mthfd2 In Complex With Th7299
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2021-07-07 Classification: OXIDOREDUCTASE Ligands: 9L9, PO4, NAD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-07-07
Ligands: 9L9, PO4, NAD
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Structure Of Human Mthfd2 In Complex With Th9619
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2021-07-07 Classification: OXIDOREDUCTASE Ligands: KUN, PO4, ADP, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-07-07
Ligands: KUN, PO4, ADP, GOL
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Sarm1 Autoinhibited Conformation
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY Release Date: 2020-08-12 Classification: HYDROLASE |
Organism: Homo sapiens
Method: ELECTRON MICROSCOPY
Release Date: 2020-08-12