Search Count: 19
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Co-Complex Cyp46A1 With Compound 3F
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.40 Å Release Date: 2022-07-27 Classification: OXIDOREDUCTASE Ligands: HEM, 0I1, EDO, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-07-27
Ligands: HEM, 0I1, EDO, GOL
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Co-Complex Cyp46A1 With 7742 (Soticlestat/Tak-935))
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2021-08-25 Classification: HYDROLASE Ligands: HEM, YBS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-08-25
Ligands: HEM, YBS
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Co-Complex Cyp46A1 With 8114 (3F)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2021-08-25 Classification: HYDROLASE Ligands: HEM, YCJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-08-25
Ligands: HEM, YCJ
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Co-Complex Cyp46A1 With 9129 (1B)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2021-08-25 Classification: HYDROLASE Ligands: HEM, YCG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-08-25
Ligands: HEM, YCG
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Structure Of Mtb Lpd Bound To 010705
Organism: Mycobacterium tuberculosis (strain atcc 25618 / h37rv)
Method: X-RAY DIFFRACTION Resolution:2.21 Å Release Date: 2021-01-27 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: FAD, WPM, GOL |
Organism: Mycobacterium tuberculosis (strain atcc 25618 / h37rv)
Method: X-RAY DIFFRACTION
Release Date: 2021-01-27
Ligands: FAD, WPM, GOL
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Human Cgas Catalytic Domain Bound With The Inhibitor G108
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2019-05-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: JUM, ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-29
Ligands: JUM, ZN
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Human Cgas Catalytic Domain Bound With The Inhibitor G150
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.41 Å Release Date: 2019-05-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ZN, JUJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-29
Ligands: ZN, JUJ
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Human Cgas Catalytic Domain Bound With Cgamp
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2019-05-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1SY, ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-29
Ligands: 1SY, ZN
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Optimization Of 3,5-Disubstitued Piperidine: Discovery Of Non-Peptide Mimetics As An Orally Active Renin Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2017-10-18 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: NAG, 7EK, PGE, PEG, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-10-18
Ligands: NAG, 7EK, PGE, PEG, DMS
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Optimization Of 3,5-Disubstitued Piperidine: Discovery Of Non-Peptide Mimetics As An Orally Active Renin Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2017-10-18 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: NAG, 7EJ, DMS, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-10-18
Ligands: NAG, 7EJ, DMS, PEG
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Discovery Of Tak-272: A Novel, Potent And Orally Active Renin In-Hibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2017-07-05 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: NAG, 6VU, PGE, PEG, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-07-05
Ligands: NAG, 6VU, PGE, PEG, DMS
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Discovery Of Tak-272: A Novel, Potent And Orally Active Renin In-Hibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.41 Å Release Date: 2016-11-16 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: NAG, 6VS, DMS, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-16
Ligands: NAG, 6VS, DMS, PEG
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Discovery Of Tak-272: A Novel, Potent And Orally Active Renin In-Hibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2016-11-02 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: NAG, 6VR, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-02
Ligands: NAG, 6VR, PEG
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Structure-Based Design Of A New Series Of N-Piperidin-3-Ylpyrimidine-5-Carboxamides As Renin Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2016-11-02 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 74U, PEG, NAG, PGE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-02
Ligands: 74U, PEG, NAG, PGE
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Structure-Based Design Of A New Series Of N-Piperidin-3-Ylpyrimidine-5-Carboxamides As Renin Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2016-11-02 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: NAG, 74V, PGE, DMS, 1PE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-02
Ligands: NAG, 74V, PGE, DMS, 1PE
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Structure-Based Design Of A New Series Of N-Piperidin-3-Ylpyrimidine-5-Carboxamides As Renin Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2016-11-02 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: NAG, 74Z, DMS, PEG, 1PE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-02
Ligands: NAG, 74Z, DMS, PEG, 1PE
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Structure-Based Design Of A New Series Of N-Piperidin-3-Ylpyrimidine-5-Carboxamides As Renin Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.85 Å Release Date: 2016-11-02 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: NAG, 74Y, PEG, PGE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-02
Ligands: NAG, 74Y, PEG, PGE
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Novel Approach Of Fragment-Based Lead Discovery Applied To Renin Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.64 Å Release Date: 2016-10-26 Classification: HYDROLASE/HYDROLASE inhibitor Ligands: NAG, PG6, DMS, 77O, PGE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-10-26
Ligands: NAG, PG6, DMS, 77O, PGE
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Crystal Structure Of Archaeal Family B Dna Polymerase Mutant
Organism: Thermococcus kodakarensis
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2005-08-02 Classification: TRANSFERASE Ligands: NI, GOL |
Organism: Thermococcus kodakarensis
Method: X-RAY DIFFRACTION
Release Date: 2005-08-02
Ligands: NI, GOL