Search Count: 11
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Cocomplex Structure Of Deoxyhypusine Synthase With Inhibitor 6-[(1R)-2-Amino-1-Phenylethyl]-3-(Pyridin-3-Yl)-4H,5H,6H,7H-Thieno[2,3-C]Pyridin-7-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.23 Å Release Date: 2020-08-19 Classification: TRANSFERASE/INHIBITOR Ligands: 8Y1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-19
Ligands: 8Y1
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Cocomplex Structure Of Deoxyhypusine Synthase With Inhibitor 6-[(2R)-1-Amino-4-Methylpentan-2-Yl]-3-(Pyridin-3-Yl)-4H,5H,6H,7H-Thieno[2,3-C]Pyridin-7-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.12 Å Release Date: 2020-08-19 Classification: TRANSFERASE/INHIBITOR Ligands: 91A |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-08-19
Ligands: 91A
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1.65 Angstrom Ternary Complex Of Deoxyhypusine Synthase With Cofactor Nad And Spermidine Mimic Inhibitor Gc7
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.65 Å Release Date: 2020-04-01 Classification: TRANSFERASE/INHIBITOR Ligands: NAD, GC7, MPD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-01
Ligands: NAD, GC7, MPD
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Cocomplex Structure Of Deoxyhypusine Synthase With Inhibitor 6-Bromo-N-(1H-Indol-4-Yl)-1-Benzothiophene-2-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2020-04-01 Classification: TRANSFERASE/INHIBITOR Ligands: 8XY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-01
Ligands: 8XY
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Discovery Of A Novel, Highly Potent, And Selective Thieno[3,2-D]Pyrimidinone-Based Cdc7 Inhibitor With A Quinuclidine Moiety (Tak-931) As An Orally Active Investigational Anti-Tumor Agent
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2020-01-15 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: O1S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-15
Ligands: O1S
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Discovery Of A Novel, Highly Potent, And Selective Thieno[3,2-D]Pyrimidinone-Based Cdc7 Inhibitor With A Quinuclidine Moiety (Tak-931) As An Orally Active Investigational Anti-Tumor Agent
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.30 Å Release Date: 2020-01-15 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: O1V |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-01-15
Ligands: O1V
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Identification Of Novel, Potent And Selective Gcn2 Inhibitors As First-In-Class Anti-Tumor Agents
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.61 Å Release Date: 2019-10-09 Classification: transferase/transferase inhibitor Ligands: KAV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-10-09
Ligands: KAV
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Identification Of Novel, Potent And Selective Gcn2 Inhibitors As First-In-Class Anti-Tumor Agents
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.01 Å Release Date: 2019-10-09 Classification: transferase/transferase inhibitor Ligands: KA4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-10-09
Ligands: KA4
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Identification Of Novel, Potent And Selective Gcn2 Inhibitors As First-In-Class Anti-Tumor Agents
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2019-10-09 Classification: transferase/transferase inhibitor Ligands: KA7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-10-09
Ligands: KA7
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Identification Of A New Class Of Potent Cdc7 Inhibitors Designed By Putative Pharmacophore Model: Synthesis And Biological Evaluation Of 2,3-Dihydrothieno[3,2-D]Pyrimidin-4(1H)-Ones
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.15 Å Release Date: 2017-03-29 Classification: TRANSFERASE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-29
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Identification Of A New Class Of Potent Cdc7 Inhibitors Designed By Putative Pharmacophore Model: Synthesis And Biological Evaluation Of 2,3-Dihydrothieno[3,2-D]Pyrimidin-4(1H)-Ones
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.33 Å Release Date: 2017-03-29 Classification: TRANSFERASE Ligands: 81G |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-03-29
Ligands: 81G