Search Count: 16
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Crystal Structure Of Btk Kinase Domain Complexed With 6-(Dimethylamino)-2-[2-(Hydroxymethyl)-3-[1-Methyl-5-[[5-(Morpholine-4-Carbonyl)-2-Pyridyl]Amino]-6-Oxo-3-Pyridyl]Phenyl]-3,4-Dihydroisoquinolin-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.12 Å Release Date: 2019-03-20 Classification: TRANSFERASE Ligands: GMQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-03-20
Ligands: GMQ
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Crystal Structure Of Btk Kinase Domain Complexed With 12-(6-Tert-Butyl-8-Fluoro-1-Oxo-Phthalazin-2-Yl)-9-Hydroxy-6-Methyl-4-[[5-(Morpholine-4-Carbonyl)-2-Pyridyl]Amino]-6-Azatricyclo[9.4.0.02,7]Pentadeca-1(15),2(7),3,11,13-Pentaen-5-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.36 Å Release Date: 2019-03-20 Classification: TRANSFERASE Ligands: GMW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-03-20
Ligands: GMW
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Crystal Structure Of Btk Kinase Domain Complexed With 6-(Dimethylamino)-2-[2-(Hydroxymethyl)-3-[1-Methyl-5-[[5-(Morpholine-4-Carbonyl)-2-Pyridyl]Amino]-6-Oxo-3-Pyridyl]Phenyl]-3,4-Dihydroisoquinolin-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2014-12-24 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3OU, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-24
Ligands: 3OU, DMS
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Crystal Structure Of Btk Kinase Domain Complexed With 6-(Dimethylamino)-8-Fluoro-2-[2-(Hydroxymethyl)-3-[1-Methyl-5-[[5-(Morpholine-4-Carbonyl)-2-Pyridyl]Amino]-6-Oxo-3-Pyridyl]Phenyl]Isoquinolin-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.17 Å Release Date: 2014-12-24 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3OV, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-24
Ligands: 3OV, DMS
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Crystal Structure Of Btk Kinase Domain Complexed With 2-[8-Fluoro-2-[2-(Hydroxymethyl)-3-[1-Methyl-5-[[5-(4-Methylpiperazin-1-Yl)-2-Pyridyl]Amino]-6-Oxo-3-Pyridyl]Phenyl]-1-Oxo-3,4-Dihydroisoquinolin-6-Yl]-2-Methyl-Propanenitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2014-12-24 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3P0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-24
Ligands: 3P0
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Crystal Structure Of Btk Kinase Domain Complexed With 4-Tert-Butyl-N-(3-{8-[4-(4-Methyl-Piperazine-1-Carbonyl)-Phenylamino]-Imidazo[1,2-A]Pyrazin-6-Yl}-Phenyl)-Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2014-05-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 481, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-14
Ligands: 481, DMS
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Crystal Structure Of Btk Kinase Domain Complexed With 4-Methanesulfonyl-N-(3-{8-[4-(Morpholine-4-Carbonyl)-Phenylamino]-Imidazo[1,2-A]Pyrazin-6-Yl}-Phenyl)-Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2014-05-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2V1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-14
Ligands: 2V1
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Crystal Structure Of Btk Kinase Domain Complexed With 1-[5-[3-(7-Tert-Butyl-4-Oxo-Quinazolin-3-Yl)-2-Methyl-Phenyl]-1-Methyl-2-Oxo-3-Pyridyl]-3-Methyl-Urea
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2014-05-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2V2, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-14
Ligands: 2V2, DMS
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Crystal Structure Of Btk Kinase Domain Complexed With 6-Cyclopropyl-2-[3-[5-[[5-(4-Ethylpiperazin-1-Yl)-2-Pyridyl]Amino]-1-Methyl-6-Oxo-3-Pyridyl]-2-(Hydroxymethyl)Phenyl]-8-Fluoro-Isoquinolin-1-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2014-05-14 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2V3, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-14
Ligands: 2V3, DMS
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Potent And Selective Inhibitors Of Pi3K-Delta: Obtaining Isoform Selectivity From The Affinity Pocket And Tryptophan Shelf
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.67 Å Release Date: 2013-04-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0SC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-17
Ligands: 0SC
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Potent And Selective Inhibitors Of Pi3K-Delta: Obtaining Isoform Selectivity From The Affinity Pocket And Tryptophan Shelf
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2013-04-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0SD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-17
Ligands: 0SD
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Potent And Selective Inhibitors Of Pi3K-Delta: Obtaining Isoform Selectivity From The Affinity Pocket And Tryptophan Shelf
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.94 Å Release Date: 2013-04-17 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0SE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-17
Ligands: 0SE
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Potent And Highly Selective Benzimidazole Inhibitors Of Pi3K-Delta
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.44 Å Release Date: 2012-08-22 Classification: transferase/transferase inhibitor Ligands: 0WR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-08-22
Ligands: 0WR
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Crystal Structure Of Spleen Tyrosine Kinase Complexed With Ym193306
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2009-03-10 Classification: TRANSFERASE Ligands: P5C |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-03-10
Ligands: P5C
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Crystal Structure Of Spleen Tyrosine Kinase Complexed With A 2-Substituted 7-Azaindole
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.26 Å Release Date: 2009-03-10 Classification: TRANSFERASE Ligands: 057 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-03-10
Ligands: 057
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Crystal Structure Of Spleen Tyrosine Kinase Complexed With R406
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2009-03-10 Classification: TRANSFERASE Ligands: 585 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-03-10
Ligands: 585