Search Count: 34
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Structure Of Human Neutrophil Elastase In Complex With A 5,8-Dihydro[1,2,4]Triazolo[4,3-A]Pyrimidin-3(2H)-One Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.14 Å Release Date: 2025-12-10 Classification: HYDROLASE Ligands: NAG, FUC, A1JN2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-12-10
Ligands: NAG, FUC, A1JN2
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Crystal Structure Of Alpha-V Beta-1 Integrin Headpiece In Complex With Tr01225179
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2025-01-01 Classification: CELL ADHESION Ligands: CA, NAG, A1AFA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-01
Ligands: CA, NAG, A1AFA
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Signal Peptide Mimicry Primes Sec61 For Client-Selective Inhibition
Organism: Synthetic construct, Ovis aries
Method: ELECTRON MICROSCOPY Release Date: 2023-03-22 Classification: MEMBRANE PROTEIN |
Organism: Synthetic construct, Ovis aries
Method: ELECTRON MICROSCOPY
Release Date: 2023-03-22
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Crystal Structure Of Human Phgdh Complexed With Compound 1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2019-07-24 Classification: OXIDOREDUCTASE/INHIBITOR Ligands: ONV, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-24
Ligands: ONV, EDO
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Crystal Structure Of Human Phgdh Complexed With Compound 15
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.93 Å Release Date: 2019-07-24 Classification: OXIDOREDUCTASE/INHIBITOR Ligands: ONS, MLT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-07-24
Ligands: ONS, MLT
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Human Cgas Catalytic Domain Bound With The Inhibitor G108
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2019-05-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: JUM, ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-29
Ligands: JUM, ZN
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Human Cgas Catalytic Domain Bound With The Inhibitor G150
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.41 Å Release Date: 2019-05-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ZN, JUJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-29
Ligands: ZN, JUJ
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Human Cgas Catalytic Domain Bound With Cgamp
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2019-05-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1SY, ZN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-29
Ligands: 1SY, ZN
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Human Glucokinase In Complex With Novel Indazole Activator.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.39 Å Release Date: 2017-05-31 Classification: transferase/transferase activator Ligands: GLC, 8WM, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-31
Ligands: GLC, 8WM, IOD
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Human Glucokinase In Complex With Novel Pyrazole Activator.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.08 Å Release Date: 2017-05-31 Classification: transferase/transferase activator Ligands: GLC, 8WJ, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-05-31
Ligands: GLC, 8WJ, IOD
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Crystal Structure Of Autotaxin/Enpp2 With A Covalent Fragment
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2017-03-15 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, CA, NAG, ACT, 6C1 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2017-03-15
Ligands: ZN, CA, NAG, ACT, 6C1
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Discovery Of Tak-659, An Orally Available Investigational Inhibitor Of Spleen Tyrosine Kinase (Syk)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2016-11-30 Classification: Transferase/Transferase Inhibitor Ligands: 7KG, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-30
Ligands: 7KG, EDO
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Discovery Of Tak-659, An Orally Available Investigational Inhibitor Of Spleen Tyrosine Kinase (Syk)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.77 Å Release Date: 2016-11-30 Classification: Transferase/Transferase Inhibitor Ligands: 7KF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-30
Ligands: 7KF
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Crystal Structure Of Dipeptidyl Peptidase Iv In Complex With Syr-472
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.24 Å Release Date: 2016-07-13 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: NAG, 6RL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-07-13
Ligands: NAG, 6RL
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Crystal Structure Of Human Gpr40 Bound To Allosteric Agonist Tak-875
Organism: Homo sapiens, Enterobacteria phage t4
Method: X-RAY DIFFRACTION Resolution:2.33 Å Release Date: 2014-07-16 Classification: Fatty acid binding protein/Hydrolase Ligands: 2YB, OLC, 1PE, DMS |
Organism: Homo sapiens, Enterobacteria phage t4
Method: X-RAY DIFFRACTION
Release Date: 2014-07-16
Ligands: 2YB, OLC, 1PE, DMS
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Crystal Structure Of Mouse Comt Bound To An Inhibitor
Organism: Mus musculus
Method: X-RAY DIFFRACTION Resolution:2.06 Å Release Date: 2014-06-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2F6 |
Organism: Mus musculus
Method: X-RAY DIFFRACTION
Release Date: 2014-06-25
Ligands: 2F6
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Parp Complexed With Benzo[1,4]Oxazin-3-One Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2013-08-07 Classification: transferase/transferase inhibitor Ligands: 1WQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-08-07
Ligands: 1WQ
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Human Glucokinase In Complex With Novel Activator (2S)-3-Cyclohexyl-2-(6-Fluoro-4-Oxoquinazolin-3(4H)-Yl)-N-(1,3-Thiazol-2-Yl)Propanamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2013-03-20 Classification: TRANSFERASE/TRANSFERASE ACTIVATOR Ligands: GLC, 1FW, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-03-20
Ligands: GLC, 1FW, IOD
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Human Glucokinase In Complex With Novel Activator (2S)-3-Cyclohexyl-2-(6-Fluoro-2,4-Dioxo-1,4-Dihydroquinazolin-3(2H)-Yl)-N-(1,3-Thiazol-2-Yl)Propanamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.09 Å Release Date: 2013-03-20 Classification: TRANSFERASE/TRANSFERASE ACTIVATOR Ligands: GLC, 1FX, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-03-20
Ligands: GLC, 1FX, IOD
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Human Glucokinase In Complex With Novel Activator (2S)-3-Cyclohexyl-2-[4-(Methylsulfonyl)-2-Oxopiperazin-1-Yl]-N-(1,3-Thiazol-2-Yl)Propanamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2013-03-20 Classification: TRANSFERASE/TRANSFERASE ACTIVATOR Ligands: GLC, 1FY, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-03-20
Ligands: GLC, 1FY, IOD