Search Count: 8
 |
Discovery Of Clinical Candidate N-{(1S)-1-[3-Fluoro-4-(Trifluoromethoxy)Phenyl]-2-Methoxyethyl}-7-Methoxy-2-Oxo-2,3-Dihydropyrido[2,3-B]Pyrazine-4(1H)-Carboxamide (Tak-915), A Highly Potent, Selective, And Brain-Penetrating Phosphodiesterase 2A Inhibitor For The Treatment Of Cognitive Disorders
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.86 Å Release Date: 2017-12-27 Classification: Hydrolase/Hydrolase Inhibitor Ligands: ZN, MG, 9GA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-12-27
Ligands: ZN, MG, 9GA
 |
Discovery Of Clinical Candidate N-{(1S)-1-[3-Fluoro-4-(Trifluoromethoxy)Phenyl]-2-Methoxyethyl}-7-Methoxy-2-Oxo-2,3-Dihydropyrido[2,3-B]Pyrazine-4(1H)-Carboxamide (Tak-915), A Highly Potent, Selective, And Brain-Penetrating Phosphodiesterase 2A Inhibitor For The Treatment Of Cognitive Disorders
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2017-08-23 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, MG, 9GJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-08-23
Ligands: ZN, MG, 9GJ
 |
Crystal Structure Of Human Phosphodiesterase 2A In Complex With 6-Methyl-N-(1-(4-(Trifluoromethoxy)Phenyl)Propyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.16 Å Release Date: 2017-08-16 Classification: HYDROLASE Ligands: MG, ZN, 87R |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-08-16
Ligands: MG, ZN, 87R
 |
Gsk3Beta Inhibitor Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2010-03-02 Classification: TRANSFERASE Ligands: G3B |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-03-02
Ligands: G3B
 |
Analysis Of The Stabilization Of Hen Lysozyme With The Helix Dipole And Charged Side Chains
Organism: Gallus gallus
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 1997-11-26 Classification: HYDROLASE |
Organism: Gallus gallus
Method: X-RAY DIFFRACTION
Release Date: 1997-11-26
 |
Analysis Of The Stabilization Of Hen Lysozyme With The Helix Dipole And Charged Side Chains
Organism: Gallus gallus
Method: X-RAY DIFFRACTION Resolution:1.71 Å Release Date: 1997-11-26 Classification: HYDROLASE |
Organism: Gallus gallus
Method: X-RAY DIFFRACTION
Release Date: 1997-11-26
 |
Analysis Of The Stabilization Of Hen Lysozyme With The Helix Dipole And Charged Side Chains
Organism: Gallus gallus
Method: X-RAY DIFFRACTION Resolution:1.79 Å Release Date: 1997-11-26 Classification: HYDROLASE |
Organism: Gallus gallus
Method: X-RAY DIFFRACTION
Release Date: 1997-11-26
 |
Analysis Of The Stabilization Of Hen Lysozyme With The Helix Dipole And Charged Side Chains
Organism: Gallus gallus
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 1997-05-15 Classification: HYDROLASE |
Organism: Gallus gallus
Method: X-RAY DIFFRACTION
Release Date: 1997-05-15