Search Count: 15
 |
8-Tetrahydropyran-2-Yl Chromans: Highly Selective Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (Bace1) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2014-12-03 Classification: hydrolase/hydrolase inhibitor Ligands: NI, 3J9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-03
Ligands: NI, 3J9
 |
8-Tetrahydropyran-2-Yl Chromans: Highly Selective Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (Bace1) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2014-12-03 Classification: hydrolase/hydrolase inhibitor Ligands: NI, 3UW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-03
Ligands: NI, 3UW
 |
8-Tetrahydropyran-2-Yl Chromans: Highly Selective Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (Bace1) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2014-12-03 Classification: hydrolase/hydrolase inhibitor Ligands: NI, 3UX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-03
Ligands: NI, 3UX
 |
8-Tetrahydropyran-2-Yl Chromans: Highly Selective Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (Bace1) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2014-12-03 Classification: hydrolase/hydrolase inhibitor Ligands: NI, 3UY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-03
Ligands: NI, 3UY
 |
Discovery Of 7-Thp Chromans: Bace1 Inhibitors That Reduce A-Beta In The Cns
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2014-05-14 Classification: hydrolase/hydrolase inhibitor Ligands: NI, 2EX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-14
Ligands: NI, 2EX
 |
Synthesis, Characterization And Pk/Pd Studies Of A Series Of Spirocyclic Pyranochromene Bace1 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2014-05-14 Classification: Hydrolase/Hydrolase inhibitor Ligands: NI, 2X4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-14
Ligands: NI, 2X4
 |
Synthesis, Characterization And Pk/Pd Studies Of A Series Of Spirocyclic Pyranochromene Bace1 Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2014-05-14 Classification: hydrolase/hydrolase inhibitor Ligands: NI, 2X5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-14
Ligands: NI, 2X5
 |
Diethylaminosulfur Trifluoride-Mediated Intramolecular Cyclization Of 2-Hydroxy-Benzylureas To Fused Bicyclic Aminooxazoline Compounds And Evaluation Of Their Biochemical Activity Against Beta-Secretase-1 (Bace1)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.38 Å Release Date: 2013-09-18 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 1W0, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-18
Ligands: 1W0, DMS
 |
Diethylaminosulfur Trifluoride-Mediated Intramolecular Cyclization Of 2-Hydroxy-Benzylureas To Fused Bicyclic Aminooxazoline Compounds And Evaluation Of Their Biochemical Activity Against Beta-Secretase-1 (Bace-1)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2013-09-18 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 1W1, ACT, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-18
Ligands: 1W1, ACT, DMS
 |
Diethylaminosulfur Trifluoride-Mediated Intramolecular Cyclization Of 2-Hydroxy-Benzylureas To Fused Bicyclic Aminooxazoline Compounds And Evaluation Of Their Biochemical Activity Against Beta-Secretase-1 (Bace-1)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.65 Å Release Date: 2013-09-18 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 1W2, ACT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-18
Ligands: 1W2, ACT
 |
Aminooxazoline Inhibitor Of Bace-1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2013-09-18 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: NI, 1WP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-09-18
Ligands: NI, 1WP
 |
Spirocyclic Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (Bace1) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2013-04-10 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: NI, 1M4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-10
Ligands: NI, 1M4
 |
Spirocyclic Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (Bace1) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2013-04-10 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: NI, 1M5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-10
Ligands: NI, 1M5
 |
Spirocyclic Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (Bace1) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2013-04-10 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: NI, 1M6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-10
Ligands: NI, 1M6
 |
Spirocyclic Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (Bace1) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2013-04-10 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: NI, 1M7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-04-10
Ligands: NI, 1M7