Search Count: 4
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Halk In Complex With Compound 7 N-((1S)-1-(5-Fluoropyridin-2-Yl)Ethyl)-1-(5-Methyl-1H-Pyrazol-3-Yl)-3-(Oxetan-3-Ylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridin-6-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2019-05-01 Classification: PROTEIN BINDING Ligands: HKJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-01
Ligands: HKJ
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Halk In Complex With Compound 9 (6-(((1S)-1-(5-Fluoropyridin-2-Yl)Ethyl)Amino)-1-(3-Methyl-1H-Pyrazol-5-Yl)-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)(Morpholin-4-Yl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.46 Å Release Date: 2019-05-01 Classification: TRANSFERASE/INHIBITOR Ligands: J3Y |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-01
Ligands: J3Y
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Halk In Complex With Compound 1 (S)-N-(1-(2,4-Difluorophenyl)Ethyl)-3-(3-Methyl-1H-Pyrazol-5-Yl)Imidazo[1,2-B]Pyridazin-6-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2019-05-01 Classification: TRANSFERASE/INHIBITOR Ligands: J4M |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-01
Ligands: J4M
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Discovery Of Clinical Candidate N-{(1S)-1-[3-Fluoro-4-(Trifluoromethoxy)Phenyl]-2-Methoxyethyl}-7-Methoxy-2-Oxo-2,3-Dihydropyrido[2,3-B]Pyrazine-4(1H)-Carboxamide (Tak-915), A Highly Potent, Selective, And Brain-Penetrating Phosphodiesterase 2A Inhibitor For The Treatment Of Cognitive Disorders
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.86 Å Release Date: 2017-12-27 Classification: Hydrolase/Hydrolase Inhibitor Ligands: ZN, MG, 9GA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-12-27
Ligands: ZN, MG, 9GA