Search Count: 23
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Taf1-Bd2 In Complex With Cpd27 (6-(But-3-En-1-Yl)-4-(1-Methyl-6-(Morpholine-4-Carbonyl)-1H-Benzo[D]Imidazol-4-Yl)-1,6-Dihydro-7H-Pyrrolo[2,3-C]Pyridin-7-One)
Organism: Oryctolagus cuniculus
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2018-11-14 Classification: Transcription/Inhibitor Ligands: G9V |
Organism: Oryctolagus cuniculus
Method: X-RAY DIFFRACTION
Release Date: 2018-11-14
Ligands: G9V
 |
Taf1-Bd2 In Complex With Cpd8 (6-(But-3-En-1-Yl)-4-(3-(Morpholine-4-Carbonyl)Phenyl)-1,6-Dihydro-7H-Pyrrolo[2,3-C]Pyridin-7-One)
Organism: Oryctolagus cuniculus
Method: X-RAY DIFFRACTION Resolution:1.30 Å Release Date: 2018-10-31 Classification: Transcription/Inhibitor Ligands: G9Y |
Organism: Oryctolagus cuniculus
Method: X-RAY DIFFRACTION
Release Date: 2018-10-31
Ligands: G9Y
 |
Brd9 In Complex With Cpd1 (6-Methyl-1,6-Dihydro-7H-Pyrrolo[2,3-C]Pyridin-7-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.04 Å Release Date: 2016-10-12 Classification: RNA BINDING PROTEIN Ligands: EDO, PEG, 67N |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-10-12
Ligands: EDO, PEG, 67N
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Brd9 In Complex With Cpd2 (N,N-Dimethyl-3-(6-Methyl-7-Oxo-6,7-Dihydro-1H-Pyrrolo[2,3-C]Pyridin-4-Yl)Benzamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.18 Å Release Date: 2016-10-12 Classification: RNA BINDING PROTEIN Ligands: 67B |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-10-12
Ligands: 67B
 |
Brd9 In Complex With Cpd4 ((E)-3-(6-(But-2-En-1-Yl)-7-Oxo-6,7-Dihydro-1H-Pyrrolo[2,3-C]Pyridin-4-Yl)-N,N-Dimethylbenzamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.45 Å Release Date: 2016-10-12 Classification: TRANSCRIPTION Ligands: 69G |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-10-12
Ligands: 69G
 |
Brd4 In Complex With Cpd2 (N,N-Dimethyl-3-(6-Methyl-7-Oxo-6,7-Dihydro-1H-Pyrrolo[2,3-C]Pyridin-4-Yl)Benzamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.45 Å Release Date: 2016-10-12 Classification: TRANSCRIPTION Ligands: 67B, EDO, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-10-12
Ligands: 67B, EDO, DMS
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Brd4 In Complex With Cpd4 ((E)-3-(6-(But-2-En-1-Yl)-7-Oxo-6,7-Dihydro-1H-Pyrrolo[2,3-C]Pyridin-4-Yl)-N,N-Dimethylbenzamide)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.40 Å Release Date: 2016-10-12 Classification: TRANSCRIPTION Ligands: PGE, EDO, DMS, 69G, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-10-12
Ligands: PGE, EDO, DMS, 69G, GOL
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Second Bromodomain Of Taf1 Bound To A Pyrrolopyridone Compound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2016-06-08 Classification: PROTEIN BINDING/INHIBITOR Ligands: 67C |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-08
Ligands: 67C
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Taf1(2) Bound To A Pyrrolopyridone Compound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.21 Å Release Date: 2016-06-08 Classification: PROTEIN BINDING/INHIBITOR Ligands: 67B, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-08
Ligands: 67B, CA
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Crystal Structure Of The Bromodomain Of Human Crebbp Bound To The Benzodiazepinone G02773986
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.35 Å Release Date: 2016-04-20 Classification: PROTEIN BINDING/INHIBITOR Ligands: SCN, 68Y |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-04-20
Ligands: SCN, 68Y
 |
Crystal Structure Of The Bromodomain Of Human Crebbp Bound To The Benzodiazepinone G02778174
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.05 Å Release Date: 2016-04-20 Classification: PROTEIN BINDING/INHIBITOR Ligands: EDO, SCN, 69A |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-04-20
Ligands: EDO, SCN, 69A
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Crystal Structure Of The Bromodomain Of Human Crebbp Bound To The Benzodiazepinone G02857790
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.07 Å Release Date: 2016-04-20 Classification: PROTEIN BINDING/INHIBITOR Ligands: ACT, CA, 69B |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-04-20
Ligands: ACT, CA, 69B
 |
Cbp In Complex With Cpd23 ((R)-6-(3-(Benzyloxy)Phenyl)-4-Methyl-1,3,4,5-Tetrahydro-2H-Benzo[B][1,4]Diazepin-2-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.52 Å Release Date: 2016-04-20 Classification: Transcription/Protein Binding Ligands: ZN, 69F, B3P, EDO, NA, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-04-20
Ligands: ZN, 69F, B3P, EDO, NA, PEG
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Cbp In Complex With Cpd637 ((R)-4-Methyl-6-(1-Methyl-3-(1-Methyl-1H-Pyrazol-4-Yl)-1H-Indazol-5-Yl)-1,3,4,5-Tetrahydro-2H-Benzo[B][1,4]Diazepin-2-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.41 Å Release Date: 2016-04-20 Classification: Transcription/Protein Binding Ligands: ZN, 69E, B3P, EDO, NA, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-04-20
Ligands: ZN, 69E, B3P, EDO, NA, PEG
 |
Crystal Structure Of The First Bromodomain Of Human Brd4 Bound To Cpi-0610
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.18 Å Release Date: 2016-02-10 Classification: TRANSCRIPTION Ligands: 62G |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-02-10
Ligands: 62G
 |
Crystal Structure Of The First Bromodomain Of Human Brd4 Bound To Benzoisoxazoloazepine 3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.40 Å Release Date: 2016-02-10 Classification: TRANSCRIPTION Ligands: 62V |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-02-10
Ligands: 62V
 |
Discovery Of Benzotriazolo Diazepines As Orally-Active Inhibitors Of Bet Bromodomains: Crystal Structure Of Brd4 With Cpi-13
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.20 Å Release Date: 2015-11-11 Classification: SIGNALING PROTEIN Ligands: FMT, 3X0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-11-11
Ligands: FMT, 3X0
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2-[2-(4-Phenyl-1H-Imidazol-2-Yl)Ethyl]Quinoxaline (Sunovion Compound 14) Co-Crystallized With Pde10A
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.31 Å Release Date: 2015-04-29 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, MG, 4F7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-04-29
Ligands: ZN, MG, 4F7
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Co-Crystal Structure Of 2-[2-(5,8-Dimethyl[1,2,4]Triazolo[1,5-A]Pyrazin-2-Yl)Ethyl]-3-Methyl-3H-Imidazo[4,5-F]Quinoline (Compound 39) With Pde10A
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2015-04-29 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: ZN, MG, 4GK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-04-29
Ligands: ZN, MG, 4GK
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Crystal Structure Of The First Bromodomain Of Human Brd4 Bound To Benzotriazolo-Diazepine Scaffold
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.40 Å Release Date: 2015-04-08 Classification: TRANSCRIPTION Ligands: 558 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-04-08
Ligands: 558