Search Count: 12
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Crystal Structure Of P110Alpha-Rbd Covalently Bound To A Breaker Compound Bbo-10203 Via Cys242
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.21 Å Release Date: 2025-06-25 Classification: ONCOPROTEIN Ligands: A1AIR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-06-25
Ligands: A1AIR
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Egfr Exon20 Insertion Mutant Asv Bound With (S)-3-((3-Chloro-2-Methoxyphenyl)Amino)-2-(3-((Tetrahydrofuran-2-Yl)Methoxy)Pyridin-4-Yl)-1,5,6,7-Tetrahydro-4H-Pyrrolo[3,2-C]Pyridin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2025-05-14 Classification: ONCOPROTEIN,TRANSFERASE/TRANSFERASE INHIBITOR Ligands: A1IMS, CL, EDO, GOL, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: A1IMS, CL, EDO, GOL, PEG
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Egfr Exon20 Insertion Mutant Svd Bound With (S)-3-((3-Chloro-2-Methoxyphenyl)Amino)-2-(3-((Tetrahydrofuran-2-Yl)Methoxy)Pyridin-4-Yl)-1,5,6,7-Tetrahydro-4H-Pyrrolo[3,2-C]Pyridin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.68 Å Release Date: 2025-05-14 Classification: ONCOPROTEIN,TRANSFERASE/TRANSFERASE INHIBITOR Ligands: A1IMS, EDO, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: A1IMS, EDO, GOL
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Egfr Exon20 Insertion Mutant Svd Bound With Stx-721
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2025-05-14 Classification: ONCOPROTEIN,TRANSFERASE/TRANSFERASE INHIBITOR Ligands: A1A4E, CL, EDO, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: A1A4E, CL, EDO, GOL
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Wildtype Egfr Bound With (R)-3-((3-Chloro-2-Methoxyphenyl)Amino)-2-(3-((Tetrahydrofuran-2-Yl)Methoxy)Pyridin-4-Yl)-1,5,6,7-Tetrahydro-4H-Pyrrolo[3,2-C]Pyridin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.12 Å Release Date: 2025-05-14 Classification: ONCOPROTEIN Ligands: A1ILZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: A1ILZ
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Egfr Exon20 Insertion Mutant Npg Bound With (S)-3-((3-Chloro-2-Methoxyphenyl)Amino)-2-(3-((Tetrahydrofuran-2-Yl)Methoxy)Pyridin-4-Yl)-1,5,6,7-Tetrahydro-4H-Pyrrolo[3,2-C]Pyridin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.88 Å Release Date: 2025-05-14 Classification: TRANSFERASE Ligands: A1IMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: A1IMS
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Egfr Exon20 Insertion Mutant Npg Bound With Stx-721
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.63 Å Release Date: 2025-05-14 Classification: TRANSFERASE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
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Wild-Type Egfr Bound With Stx-721
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2025-05-14 Classification: TRANSFERASE Ligands: CL, A1IMT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: CL, A1IMT
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Structure Of Human Anaplastic Lymphoma Kinase (Alk) Harboring The G1202R/L1196M Compound Mutation In Complex With Nvl-655
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.58 Å Release Date: 2024-09-18 Classification: ONCOPROTEIN Ligands: A1IJ8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-09-18
Ligands: A1IJ8
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Nf-Kappa-B1 Bound With A Covalent Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.02 Å Release Date: 2024-04-24 Classification: TRANSCRIPTION Ligands: JMR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-04-24
Ligands: JMR
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Structure Of Human Anaplastic Lymphoma Kinase Domain In Complex With (4-[6-Amino-5-[(1~{R})-1-[5-Fluoro-2-(Triazol-2-Yl)Phenyl]Ethoxy]-3-Pyridyl]Isoindolin-1-One)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.83 Å Release Date: 2022-06-29 Classification: TRANSFERASE Ligands: 25J |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-06-29
Ligands: 25J
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Structure Of Human Anaplastic Lymphoma Kinase Domain In Complex With ((2~{R})-2-[5-[6-Amino-5-[(1~{R})-1-[5-Fluoro-2-(Triazol-2-Yl)Phenyl]Ethoxy]-3-Pyridyl]-4-Methyl-Thiazol-2-Yl]Propane-1,2-Diol)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2022-06-29 Classification: TRANSFERASE Ligands: AWJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-06-29
Ligands: AWJ