Search Count: 13
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Crystal Structure Of Cyp46A1 With [(1R,5S)-3-Oxa-8-Azabicyclo[3.2.1]Octan-8-Yl][(4R,8M)-8-(1,3-Oxazol-5-Yl)-6-(Trifluoromethyl)Imidazo[1,2-A]Pyridin-3-Yl]Methanone (Compound 3K)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.67 Å Release Date: 2025-07-02 Classification: HYDROLASE/INHIBITOR Ligands: HEM, A1BZE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-07-02
Ligands: HEM, A1BZE
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Crystal Structure Of Cyp46A1 With (Morpholin-4-Yl)[(4R,8M)-8-(1,3-Oxazol-5-Yl)-6-(Trifluoromethyl)Imidazo[1,2-A]Pyridin-3-Yl]Methanone (Compound 2H)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2025-07-02 Classification: HYDROLASE/INHIBITOR Ligands: HEM, A1BZD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-07-02
Ligands: HEM, A1BZD
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Crystal Structure Of Cyp46A1 With Cyclopropyl[(4M)-4-(1,3-Oxazol-5-Yl)-6-(Trifluoromethyl)-1H-Indol-1-Yl]Methanone (Compound 2B)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2025-07-02 Classification: HYDROLASE/INHIBITOR Ligands: HEM, A1BZC, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-07-02
Ligands: HEM, A1BZC, EDO
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Halk In Complex With Compound 7 N-((1S)-1-(5-Fluoropyridin-2-Yl)Ethyl)-1-(5-Methyl-1H-Pyrazol-3-Yl)-3-(Oxetan-3-Ylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridin-6-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2019-05-01 Classification: PROTEIN BINDING Ligands: HKJ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-01
Ligands: HKJ
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Halk In Complex With Compound 9 (6-(((1S)-1-(5-Fluoropyridin-2-Yl)Ethyl)Amino)-1-(3-Methyl-1H-Pyrazol-5-Yl)-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)(Morpholin-4-Yl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.46 Å Release Date: 2019-05-01 Classification: TRANSFERASE/INHIBITOR Ligands: J3Y |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-01
Ligands: J3Y
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Halk In Complex With Compound 1 (S)-N-(1-(2,4-Difluorophenyl)Ethyl)-3-(3-Methyl-1H-Pyrazol-5-Yl)Imidazo[1,2-B]Pyridazin-6-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2019-05-01 Classification: TRANSFERASE/INHIBITOR Ligands: J4M |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-05-01
Ligands: J4M
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Crystal Structure Of The Catalytic Domain Of Human Pde10A Complexed With N-(4-((5-Methyl-5H-Pyrrolo[3,2-D]Pyrimidin-4-Yl)Oxy)Phenyl)-1H-Benzimidazol-2-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2016-06-29 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: MG, ZN, 6DT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-29
Ligands: MG, ZN, 6DT
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Crystal Structure Of The Catalytic Domain Of Human Pde10A Complexed With 1-(Cyclopropylmethyl)-5-(2-(2,3-Dihydro-1H-Imidazo[1,2-A]Benzimidazol-1-Yl)Ethoxy)-3-(1-Phenyl-1H-Pyrazol-5-Yl)Pyridazin-4(1H)-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2016-06-29 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: MG, ZN, 6DW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-29
Ligands: MG, ZN, 6DW
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Mineralocorticoid Receptor Ligand-Binding Domain With Compuond 37A
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.10 Å Release Date: 2014-11-26 Classification: TRANSCRIPTION/TRANSCRIPTION INHIBITOR Ligands: HFN, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-11-26
Ligands: HFN, EDO
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Mineralocorticoid Receptor Ligand-Binding Domain With Compound 2B
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.05 Å Release Date: 2013-08-21 Classification: TRANSCRIPTION/INHIBITOR Ligands: WFF, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-08-21
Ligands: WFF, PO4
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Mineralocorticoid Receptor Ligand-Binding Domain With Compuond 2E
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.40 Å Release Date: 2013-08-21 Classification: TRANSCRIPTION/INHIBITOR Ligands: WFG, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-08-21
Ligands: WFG, EDO
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Mineralocorticoid Receptor Ligand-Binding Domain With Spironolactone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.11 Å Release Date: 2011-12-28 Classification: TRANSCRIPTION/INHIBITOR Ligands: SNL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-12-28
Ligands: SNL
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Mineralocorticoid Receptor Ligand-Binding Domain With Non-Steroidal Antagonist
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.35 Å Release Date: 2011-12-28 Classification: TRANSCRIPTION/INHIBITOR Ligands: LD1, LD2, EDO, K |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-12-28
Ligands: LD1, LD2, EDO, K