Search Count: 36
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Crystal Structure Of Sterol 14 Alpha-Demethylase (Cyp51) From Deep-Sea Fish Coryphaenoides Armatus (Abyssal Grenadier) In The Ligand-Free State
Organism: Coryphaenoides armatus
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2025-06-25 Classification: OXIDOREDUCTASE Ligands: HEM |
Organism: Coryphaenoides armatus
Method: X-RAY DIFFRACTION
Release Date: 2025-06-25
Ligands: HEM
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Em Structure Of Cytochrome P450 Reductase
Organism: Rattus norvegicus
Method: ELECTRON MICROSCOPY Release Date: 2024-12-04 Classification: OXIDOREDUCTASE Ligands: FMN, FAD |
Organism: Rattus norvegicus
Method: ELECTRON MICROSCOPY
Release Date: 2024-12-04
Ligands: FMN, FAD
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Human Sterol 14 Alpha-Demethylase (Cyp51) In Complex With The Reaction Intermediate 14 Alpha-Aldehyde Dihydrolanosterol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2024-01-17 Classification: OXIDOREDUCTASE Ligands: HEM, WQR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-01-17
Ligands: HEM, WQR
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Cyp51 From Acanthamoeba Castellanii In Complex With The Tetrazole-Based Ind Inhibitor Vt-1161(Vt1)
Organism: Acanthamoeba castellanii
Method: X-RAY DIFFRACTION Resolution:2.29 Å Release Date: 2023-08-02 Classification: OXIDOREDUCTASE/INHIBITOR Ligands: HEM, VT1 |
Organism: Acanthamoeba castellanii
Method: X-RAY DIFFRACTION
Release Date: 2023-08-02
Ligands: HEM, VT1
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Detergent-Bound Cyp51 From Acanthamoeba Castellanii
Organism: Acanthamoeba castellanii
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2023-04-12 Classification: OXIDOREDUCTASE Ligands: HEM, LMT |
Organism: Acanthamoeba castellanii
Method: X-RAY DIFFRACTION
Release Date: 2023-04-12
Ligands: HEM, LMT
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Crystal Structure Of Human Sterol 14 Alpha-Demethylase (Cyp51) In The Ligand-Free State
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.73 Å Release Date: 2023-04-12 Classification: OXIDOREDUCTASE Ligands: HEM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-04-12
Ligands: HEM
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Lanosterol-Bound P450 Domain Of The Cyp51-Ferredoxin Fusion Protein From Methylococcus Capsulatus
Organism: Methylococcus capsulatus (strain atcc 33009 / ncimb 11132 / bath)
Method: X-RAY DIFFRACTION Resolution:2.55 Å Release Date: 2022-10-05 Classification: OXIDOREDUCTASE Ligands: HEM, LAN |
Organism: Methylococcus capsulatus (strain atcc 33009 / ncimb 11132 / bath)
Method: X-RAY DIFFRACTION
Release Date: 2022-10-05
Ligands: HEM, LAN
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Sterol 14Alpha Demethylase (Cyp51) From Naegleria Fowleri In Complex With An Inhibitor R)-N-(1-(3,4'-Difluorobiphenyl-4-Yl)-2-(1H-Imidazol-1-Yl)Ethyl)-4-(5-Phenyl-1,3,4-Oxadiazol-2-Yl)Benzamide
Organism: Naegleria fowleri
Method: X-RAY DIFFRACTION Resolution:2.11 Å Release Date: 2021-11-24 Classification: OXIDOREDUCTASE Ligands: HEM, 7PW |
Organism: Naegleria fowleri
Method: X-RAY DIFFRACTION
Release Date: 2021-11-24
Ligands: HEM, 7PW
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Human Sterol 14A-Demethylase (Cyp51) In Complex With The Substrate Lanosterol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2020-06-10 Classification: OXIDOREDUCTASE Ligands: HEM, LAN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-06-10
Ligands: HEM, LAN
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Human Sterol 14A-Demethylase (Cyp51) In Complex With The Functionally Irreversible Inhibitor (R)-N-(1-(3-Chloro-4'-Fluoro-[1,1'-Biphenyl]-4-Yl)-2-(1H-Imidazol-1-Yl)Ethyl)-4-(5-(3-Fluoro-5-(5-Fluoropyrimidin-4-Yl)Phenyl)-1,3,4-Oxadiazol-2-Yl)Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.80 Å Release Date: 2019-11-13 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: HEM, PJM, DXC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-11-13
Ligands: HEM, PJM, DXC
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Crystal Structure Of The P450 Domain Of The Cyp51-Ferredoxin Fusion Protein From Methylococcus Capsulatus, Complex With The Detergent Anapoe-X-114
Organism: Methylococcus capsulatus (strain atcc 33009 / ncimb 11132 / bath)
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2019-07-10 Classification: OXIDOREDUCTASE Ligands: JDJ, HEM |
Organism: Methylococcus capsulatus (strain atcc 33009 / ncimb 11132 / bath)
Method: X-RAY DIFFRACTION
Release Date: 2019-07-10
Ligands: JDJ, HEM
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Crystal Structure Of The P450 Domain Of The Cyp51-Ferredoxin Fusion Protein From Methylococcus Capsulatus, Ligand-Free State
Organism: Methylococcus capsulatus (strain atcc 33009 / ncimb 11132 / bath)
Method: X-RAY DIFFRACTION Resolution:2.73 Å Release Date: 2019-07-10 Classification: OXIDOREDUCTASE Ligands: HEM |
Organism: Methylococcus capsulatus (strain atcc 33009 / ncimb 11132 / bath)
Method: X-RAY DIFFRACTION
Release Date: 2019-07-10
Ligands: HEM
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Crystal Structure Of The Substrate (Obtusifoliol)-Bound And Ligand-Free I105F Mutant Of Sterol 14-Alpha Demethylase (Cyp51) From Trypanosoma Cruzi
Organism: Trypanosoma cruzi
Method: X-RAY DIFFRACTION Resolution:3.18 Å Release Date: 2018-10-24 Classification: PROTEIN BINDING Ligands: HEM, DVE |
Organism: Trypanosoma cruzi
Method: X-RAY DIFFRACTION
Release Date: 2018-10-24
Ligands: HEM, DVE
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Crystal Structure Of Sterol 14-Alpha Demethylase (Cyp51B) From Aspergillus Fumigatus In Complex With The Vni Derivative N-(1-(2,4-Dichlorophenyl)-2-(1H-Imidazol-1-Yl)Ethyl)-4-(5-(2-Fluoro-4-(2,2,2-Trifluoroethoxy)Phenyl)-1,3,4-Oxadiazol-2-Yl)Benzamide
Organism: Aspergillus fumigatus
Method: X-RAY DIFFRACTION Resolution:2.38 Å Release Date: 2018-06-27 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: HEM, LFV |
Organism: Aspergillus fumigatus
Method: X-RAY DIFFRACTION
Release Date: 2018-06-27
Ligands: HEM, LFV
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Crystal Structure Of Sterol 14-Alpha Demethylase (Cyp51B) From A Pathogenic Filamentous Fungus Aspergillus Fumigatus In Complex With A Tetrazole-Based Inhibitor Vt-1598
Organism: Aspergillus fumigatus
Method: X-RAY DIFFRACTION Resolution:2.99 Å Release Date: 2017-04-26 Classification: OXIDOREDUCTASE Ligands: HEM, VT2 |
Organism: Aspergillus fumigatus
Method: X-RAY DIFFRACTION
Release Date: 2017-04-26
Ligands: HEM, VT2
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Crystal Structure Of Sterol 14-Alpha Demethylase (Cyp51) From A Pathogenic Yeast Candida Albicans In Complex With The Antifungal Drug Posaconazole
Organism: Candida albicans
Method: X-RAY DIFFRACTION Resolution:2.86 Å Release Date: 2017-03-15 Classification: OXIDOREDUCTASE Ligands: HEM, X2N |
Organism: Candida albicans
Method: X-RAY DIFFRACTION
Release Date: 2017-03-15
Ligands: HEM, X2N
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Crystal Structure Of Sterol 14-Alpha Demethylase (Cyp51) From Candida Albicans In Complex With The Tetrazole-Based Antifungal Drug Candidate Vt1161 (Vt1)
Organism: Candida albicans
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2017-03-15 Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR Ligands: HEM, VT1 |
Organism: Candida albicans
Method: X-RAY DIFFRACTION
Release Date: 2017-03-15
Ligands: HEM, VT1
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Human Sterol 14-Alpha Demethylase (Cyp51) In Complex With Vfv In P1 Space Group
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2016-06-15 Classification: OXIDOREDUCTASE Ligands: HEM, VFV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-15
Ligands: HEM, VFV
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Human Sterol 14-Alpha Demethylase (Cyp51) In Complex With Vfv In C121 Space Group
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.04 Å Release Date: 2016-06-08 Classification: OXIDOREDUCTASE Ligands: HEM, VFV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-06-08
Ligands: HEM, VFV
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Sterol 14-Alpha Demethylase (Cyp51) From Trypanosoma Cruzi In Complex With The 1-Tetrazole Derivative Vt-1161 ((R)-2-(2,4-Difluorophenyl)-1, 1-Difluoro-3-(1H-Tetrazol-1-Yl)-1-(5-(4-(2,2,2-Trifluoroethoxy)Phenyl) Pyridin-2-Yl)Propan-2-Ol)
Organism: Trypanosoma cruzi
Method: X-RAY DIFFRACTION Resolution:2.75 Å Release Date: 2015-12-02 Classification: OXIDOREDUCTASE Ligands: HEM, VT1 |
Organism: Trypanosoma cruzi
Method: X-RAY DIFFRACTION
Release Date: 2015-12-02
Ligands: HEM, VT1