Search Count: 8
 |
Crystal Structure Of Beta-Site App-Cleaving Enzyme 1 Complexed With N-(3-((4As,7As)-2-Amino-4,4A,5,6-Tetrahydro-7Ah-Furo[2,3-D][1,3]Thiazin-7A-Yl)-4-Fluorophenyl)-5-Bromo-2-Pyridinecarboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.51 Å Release Date: 2016-11-23 Classification: HYDROLASE Ligands: 7H3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-23
Ligands: 7H3
 |
Compound 10
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2016-10-05 Classification: Hydrolase/Hydrolase Inhibitor Ligands: GOL, IOD, 5QU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-10-05
Ligands: GOL, IOD, 5QU
 |
(4~{S},6~{S})-4-[2,4-Bis(Fluoranyl)Phenyl]-4-Methyl-6-Pyrimidin-5-Yl-5,6-Dihydro-1,3-Thiazin-2-Amine (Compound 12) Bound To Bace1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2016-09-07 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 6WD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-09-07
Ligands: 6WD
 |
(4~{S},6~{S})-4-[2,4-Bis(Fluoranyl)Phenyl]-6-(3,5-Dimethyl-1,2-Oxazol-4-Yl)-4-Methyl-5,6-Dihydro-1,3-Thiazin-2-Amine (Compound 5) Bound To Bace1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.12 Å Release Date: 2016-09-07 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: IOD, 6WE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-09-07
Ligands: IOD, 6WE
 |
Compound 18
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.11 Å Release Date: 2016-07-06 Classification: Hydrolase/Hydrolase Inhibitor Ligands: GOL, IOD, 5QV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-07-06
Ligands: GOL, IOD, 5QV
 |
Crystal Structure Of Beta-Site App-Cleaving Enzyme 1 (Bace-Wt) Complex With (2S)-2-((3R)-3-Acetamido-3-Isobutyl-2-Oxo-1-Pyrrolidinyl)-N-((1S,2R)-1-(3,5-Difluorobenzyl)-2-Hydroxy-2-(1,2,3,4-Tetrahydro-3-Isoquinolinyl)Ethyl)-4-Phenylbutanamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.88 Å Release Date: 2011-09-07 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: PB8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-09-07
Ligands: PB8
 |
Crystal Structure Of Beta-Site App-Cleaving Enzyme 1 (Bace-Wt) Complex With Bms-693391 Aka (2S)-2-((3R)-3-Acetamido-3-Isobutyl-2-Oxo-1-Pyrrolidinyl)-N-((1S,2R)-1-(3,5-Difluorobenzyl)-2-Hydroxy-2-((2R,4R)-4-Propoxy-2-Pyrrolidinyl)Ethyl)-4-Phenylbutanamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.53 Å Release Date: 2011-08-31 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: PB0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-08-31
Ligands: PB0
 |
Crystal Structure Of Beta-Site App-Cleaving Enzyme 1 (Bace-Wt) Complex With (2S)-2-((3S)-3-(Acetylamino)-3-(Butan-2-Yl)-2-Oxopyrrolidin-1-Yl)-N-((2S,3R)-3-Hydroxy-4-((3-Methoxybenzyl)Amino)-1-Phenylbutan-2-Yl)-4-Phenylbutanamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.00 Å Release Date: 2011-08-31 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: PB7, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-08-31
Ligands: PB7, IOD