Search Count: 13
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Selective Inhibition Of Autotaxin Is Effective In Mouse Models Of Liver Fibrosis
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.59 Å Release Date: 2016-11-09 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: NAG, ZN, CA, 6Y7, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-09
Ligands: NAG, ZN, CA, 6Y7, PO4
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Structural Basis For Inhibition Of Human Autotaxin By Four Novel Compounds
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2015-10-14 Classification: Hydrolase/Hydrolase Inhibitor Ligands: ZN, CA, NA, GOL, 4NY, SCN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-10-14
Ligands: ZN, CA, NA, GOL, 4NY, SCN
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Structural Basis For Inhibition Of Human Autotaxin By Four Novel Compounds
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2015-10-14 Classification: Hydrolase/Hydrolase Inhibitor Ligands: ZN, CA, NA, 4O0, NKN, GOL, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-10-14
Ligands: ZN, CA, NA, 4O0, NKN, GOL, CL
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Structural Basis For Inhibition Of Human Autotaxin By Four Novel Compounds
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.95 Å Release Date: 2015-10-14 Classification: Hydrolase/Hydrolase Inhibitor Ligands: ZN, CA, NA, 4O2, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-10-14
Ligands: ZN, CA, NA, 4O2, EDO
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Structural Basis For Inhibition Of Human Autotaxin By Four Novel Compounds
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2015-10-14 Classification: Hydrolase/Hydrolase Inhibitor Ligands: ZN, CA, EDO, SCN, ACD, 4O3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-10-14
Ligands: ZN, CA, EDO, SCN, ACD, 4O3
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Identification Of Novel Hsp90/Isoform Selective Inhibitors Using Structure-Based Drug Design. Demonstration Of Potential Utility In Treating Cns Disorders Such As Huntington'S Disease
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.82 Å Release Date: 2014-12-24 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 2Q8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-24
Ligands: 2Q8
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Identification Of Novel Hsp90/Isoform Selective Inhibitors Using Structure-Based Drug Design. Demonstration Of Potential Utility In Treating Cns Disorders Such As Huntington'S Disease
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.79 Å Release Date: 2014-04-09 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 2Q9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-09
Ligands: 2Q9
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Identification Of Novel Hsp90/Isoform Selective Inhibitors Using Structure-Based Drug Design. Demonstration Of Potential Utility In Treating Cns Disorders Such As Huntington'S Disease
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.86 Å Release Date: 2014-04-09 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: FGH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-09
Ligands: FGH
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Identification Of Novel Hsp90 / Isoform Selective Inhibitors Using Structure-Based Drug Design. Demonstration Of Potential Utility In Treating Cns Disorders Such As Huntington S Disease
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2014-04-09 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 2R6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-09
Ligands: 2R6
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Identification Of Novel Hsp90/Isoform Selective Inhibitors Using Structure-Based Drug Design. Demonstration Of Potential Utility In Treating Cns Disorders Such As Huntington'S Disease
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2014-04-09 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 2QA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-04-09
Ligands: 2QA
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Catalytic Unit Of Pi3Kg In Complex With Pi3K/Mtor Dual Inhibitor Pf-04979064
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2013-11-20 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 19P |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-11-20
Ligands: 19P
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Discovery Of The Highly Potent Pi3K/Mtor Dual Inhibitor Pf-04691502 Through Structure Based Drug Design
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.70 Å Release Date: 2010-06-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ML8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-06-02
Ligands: ML8
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Discovery Of The Highly Potent Pi3K/Mtor Dual Inhibitor Pf-04691502 Through Structure Based Drug Design
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.55 Å Release Date: 2010-06-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: ML9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-06-02
Ligands: ML9