Search Count: 3
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Discovery Of A Stable Macrocyclic O-Aminobenzamide Hsp90 Inhibitor Capable Of Significantly Decreasing Tumor Volume In A Mouse Xenograft Model.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.57 Å Release Date: 2011-07-13 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 06T |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-07-13
Ligands: 06T
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Discovery Of A Macrocyclic O-Aminobenzamide Hsp90 Inhibitor With Heterocyclic Tether That Shows Extended Biomarker Activity And In Vivo Efficacy In A Mouse Xenograft Model.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.58 Å Release Date: 2011-06-08 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 06J |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-06-08
Ligands: 06J
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Macrocyclic Lactams As Potent Hsp90 Inhibitors With Excellent Tumor Exposure And Extended Biomarker Activity.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.58 Å Release Date: 2011-05-11 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 06H |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-05-11
Ligands: 06H