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Search Count: 25

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9MUL image
Crystal Structure Of Glun1/Glun2A Ligand-Binding Domain In Complex With Compound 1, Glycine And Glutamate

9MUM image
Crystal Structure Of Glun1/Glun2A Ligand-Binding Domain In Complex With Compound 11, Glycine And Glutamate

9MGY image
Cryo-Em Structure Of Human Nlrp3 Complex With Compound 1

9MIE image
Human Nlrp3 Complex With Compound 2 In The Closed Hexamer

9MIG image
Cryo-Em Structure Of Human Nlrp3 Complex With Compound 3

7F1D image
Crystal Structure Of Bace1 In Complex With N-{3-[(4R,5R,6R)-2-Amino-5-Fluoro-4,6-Dimethyl-5,6-Dihydro-4H-1,3-Thiazin-4-Yl]-4-Fluorophenyl}-2H,3H-[1,4]Dioxino[2,3-C]Pyridine-7-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.05 Å Release Date: 2022-02-23
Classification: HYDROLASE
Ligands: IOD, 0QQ

7F1G image
Bace2 Xaperone Complex With N-{3-[(4R,5R,6R)-2-Amino-5-Fluoro-4,6-Dimethyl-5,6-Dihydro-4H-1,3-Thiazin-4-Yl]-4-Fluorophenyl}-2H,3H-[1,4]Dioxino[2,3-C]Pyridine-7-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.50 Å Release Date: 2022-02-23
Classification: HYDROLASE
Ligands: 0QQ

7N4N image
Bace-2 In Complex With Ligand 36

7N66 image
Bace-1 In Complex With Ligand 12

7D2V image
Crystal Structure Of Bace1 In Complex With N-{3-[(5R)-3-Amino-2,5-Dimethyl-1,1-Dioxo-5,6-Dihydro-2H-1Lambda6,2,4-Thiadiazin-5-Yl]-4-Fluorophenyl}-5-Fluoropyridine-2-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.10 Å Release Date: 2021-03-31
Classification: HYDROLASE
Ligands: IOD, GOL, 66F

7D2X image
Crystal Structure Of Bace1 In Complex With N-{3-[(4R)-2-Amino-4-(Prop-1-Yn-1-Yl)-5,6-Dihydro-4H-1,3-Oxazin-4-Yl]-4-Fluorophenyl}-5-Cyanopyridine-2-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.45 Å Release Date: 2021-03-31
Classification: HYDROLASE
Ligands: IOD, GOL, GTU

7D5A image
Crystal Structure Of Bace1 In Complex With N-{3-[(9S)-7-Amino-2,2-Difluoro-9-(Prop-1-Yn-1-Yl)-6-Oxa-8-Azaspiro[3.5]Non-7-En-9-Yl]-4-Fluorophenyl}-5-Cyanopyridine-2-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.20 Å Release Date: 2021-03-31
Classification: HYDROLASE
Ligands: IOD, GOL, GX6

7D5B image
Bace2 Xaperone Complex With N-{3-[(5R)-3-Amino-2,5-Dimethyl-1,1-Dioxo-5,6-Dihydro-2H-1Lambda6,2,4-Thiadiazin-5-Yl]-4-Fluorophenyl}-5-Fluoropyridine-2-Carboxamide

7D5U image
Bace2 Xaperone Complex With N-{3-[(9S)-7-Amino-2,2-Difluoro-9-(Prop-1-Yn-1-Yl)-6-Oxa-8-Azaspiro[3.5]Non-7-En-9-Yl]-4-Fluorophenyl}-5-Cyanopyridine-2-Carboxamide

6JT4 image
Crystal Structure Of Bace1 In Complex With N-{3-[(4S,6S)-2-Amino-4-Methyl-6-(Trifluoromethyl)-5,6-Dihydro-4H-1,3-Thiazin-4-Yl]-4-Fluorophenyl}-5-(Fluoromethoxy)Pyrazine-2-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.20 Å Release Date: 2020-01-15
Classification: HYDROLASE
Ligands: IOD, GOL, C86

6JT3 image
Crystal Structure Of Bace1 In Complex With N-{3-[(4R,5R,6R)-2-Amino-5-Fluoro-4,6-Dimethyl-5,6-Dihydro-4H-1,3-Thiazin-4-Yl]-4-Fluorophenyl}-5-(Fluoromethoxy)Pyrazine-2-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.40 Å Release Date: 2019-10-30
Classification: HYDROLASE
Ligands: IOD, GOL, DMS, C83

6OD6 image
Structure Of Bace-1 In Complex With Ligand 13

6E3Z image
Structure Of Bace-1 In Complex With Ligand 8

6JSE image
Crystal Structure Of Bace1 In Complex With N-(3-((4S,5R)-2-Amino-4-Methyl-5-Phenyl-5,6-Dihydro-4H-1,3-Thiazin-4-Yl)-4-Fluorophenyl)-5-(Fluoromethoxy)Pyrazine-2-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.00 Å Release Date: 2019-08-28
Classification: HYDROLASE
Ligands: IOD, DMS, C6R

6JSF image
Crystal Structure Of Bace1 In Complex With N-(3-((4S,5S)-2-Amino-4-Methyl-5-Phenyl-5,6-Dihydro-4H-1,3-Thiazin-4-Yl)-4-Fluorophenyl)-5-(Fluoromethoxy)Pyrazine-2-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.30 Å Release Date: 2019-08-28
Classification: HYDROLASE
Ligands: IOD, DMS, C7X
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