Search Count: 34
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Discovery Of A Small Molecule Itk And Pan-Trk Kinase Inhibitor (Pf-07245303) For The Potential Topical Treatment Of Atopic Dermatitis
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.35 Å Release Date: 2025-11-19 Classification: SIGNALING PROTEIN Ligands: A1B66 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-11-19
Ligands: A1B66
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Cryo-Em Structure Of Ccr6 Bound By Pf-07054894 And Oxm2
Organism: Homo sapiens, Synthetic construct
Method: ELECTRON MICROSCOPY Resolution:3.35 Å Release Date: 2025-10-01 Classification: MEMBRANE PROTEIN Ligands: A1A1W, A1CH1 |
Organism: Homo sapiens, Synthetic construct
Method: ELECTRON MICROSCOPY
Release Date: 2025-10-01
Ligands: A1A1W, A1CH1
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Cryo-Em Structure Of Ccr6 Bound By Sqa1 And Oxm2
Organism: Homo sapiens, Synthetic construct
Method: ELECTRON MICROSCOPY Release Date: 2024-09-11 Classification: MEMBRANE PROTEIN Ligands: CLR, EBX, A1A1W |
Organism: Homo sapiens, Synthetic construct
Method: ELECTRON MICROSCOPY
Release Date: 2024-09-11
Ligands: CLR, EBX, A1A1W
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Cryo-Em Structure Of Ccr6 Bound By Sqa1 And Oxm1
Organism: Homo sapiens, Synthetic construct
Method: ELECTRON MICROSCOPY Release Date: 2024-09-11 Classification: MEMBRANE PROTEIN Ligands: CLR, EBX, A1A2A |
Organism: Homo sapiens, Synthetic construct
Method: ELECTRON MICROSCOPY
Release Date: 2024-09-11
Ligands: CLR, EBX, A1A2A
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Crystal Structure Of Jak2 With Compound 11
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2020-11-25 Classification: TRANSFERASE Ligands: UWP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-11-25
Ligands: UWP
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Crystal Structure Of Tyk2 With Compound 11
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2020-11-25 Classification: TRANSFERASE Ligands: UWP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-11-25
Ligands: UWP
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Crystal Structure Of Tyk2 With Compound 22
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.21 Å Release Date: 2020-11-25 Classification: TRANSFERASE Ligands: UWM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-11-25
Ligands: UWM
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Crystal Structure Of Tyk2 Kinase With Compound 13
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.09 Å Release Date: 2020-04-08 Classification: TRANSFERASE/INHIBITOR Ligands: R5D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-08
Ligands: R5D
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Crystal Structure Of Tyk2 Kinase With Compound 14
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2020-04-08 Classification: TRANSFERASE/INHIBITOR Ligands: R4Y |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-08
Ligands: R4Y
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Crystal Structure Of Tyk2 Kinase With Compound 19
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.18 Å Release Date: 2020-04-08 Classification: TRANSFERASE/INHIBITOR Ligands: R4V |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-08
Ligands: R4V
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Crystal Structure Of Tyk2 Kinase With Compound 10
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2020-04-08 Classification: TRANSFERASE/INHIBITOR Ligands: R4S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-08
Ligands: R4S
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Crystal Structure Of Jak1 Kinase With Compound 10
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.11 Å Release Date: 2020-04-08 Classification: TRANSFERASE/INHIBITOR Ligands: R4S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-08
Ligands: R4S
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Tyk2 With Compound 8
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2018-08-29 Classification: TRANSFERASE Ligands: G5D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-08-29
Ligands: G5D
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Tyk2 With Compound 23
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.37 Å Release Date: 2018-08-29 Classification: TRANSFERASE Ligands: G4J |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-08-29
Ligands: G4J
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Jak1 With Compound 23
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.48 Å Release Date: 2018-08-29 Classification: TRANSFERASE Ligands: G4J |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-08-29
Ligands: G4J
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Crystal Structure Of The Bromodomain Of Human Brd1 (Brpf2) In Complex With Of-1 Chemical Probe
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.10 Å Release Date: 2016-02-03 Classification: TRANSCRIPTION Ligands: EDO, 5XE, NI, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-02-03
Ligands: EDO, 5XE, NI, PO4
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Crystal Structure Of The Bromodomain Of Human Brpf1 In Complex With Of-1 Chemical Probe
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.65 Å Release Date: 2016-01-13 Classification: TRANSCRIPTION Ligands: 5XE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-01-13
Ligands: 5XE
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Crystal Structure Of The Bromodomain Of Human Brpf1 In Complex With Pfi-4 Chemical Probe
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2015-12-30 Classification: TRANSCRIPTION Ligands: 5XF, NO3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-12-30
Ligands: 5XF, NO3
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Crystal Structure Of The Bromodomain Of Human Brm (Smarca2) In Complex With Pfi-3 Chemical Probe
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2015-10-14 Classification: HYDROLASE Ligands: ZN, 5BW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-10-14
Ligands: ZN, 5BW
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Crystal Structure Of The Bromodomain Of Human Brg1 (Smarca4) In Complex With Pfi-3 Chemical Probe
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2015-10-14 Classification: HYDROLASE Ligands: ZN, EDO, 5BW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-10-14
Ligands: ZN, EDO, 5BW