Search Count: 17
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Crystal Structure Of Human Naa50 In Complex With A Cofactor Derived Inhibitor (Compound 1)
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:2.29 Å Release Date: 2020-07-01 Classification: TRANSFERASE/INHIBITOR Ligands: COA |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2020-07-01
Ligands: COA
 |
Crystal Structure Of Human Naa50 In Complex With A Truncated Cofactor Derived Inhibitor (Compound 2)
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:2.04 Å Release Date: 2020-07-01 Classification: TRANSFERASE/INHIBITOR Ligands: U44 |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2020-07-01
Ligands: U44
 |
Crystal Structure Of Human Naa50 In Complex With An Inhibitor (Compound 3) Identified Using Dna Encoded Library Technology
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.16 Å Release Date: 2020-07-01 Classification: TRANSFERASE/INHIBITOR Ligands: COA, U3V |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-07-01
Ligands: COA, U3V
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Crystal Structure Of Human Naa50 In Complex With Coa And An Inhibitor (Compound 4A) Identified Using Dna Encoded Library Technology
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.87 Å Release Date: 2020-07-01 Classification: TRANSFERASE Ligands: COA, U2J |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-07-01
Ligands: COA, U2J
 |
Crystal Structure Of Human Naa50 In Complex With Accoa And An Inhibitor (Compound 4A) Identified Using Dna Encoded Library Technology
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.07 Å Release Date: 2020-07-01 Classification: TRANSFERASE/INHIBITOR Ligands: ACO, U2J |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-07-01
Ligands: ACO, U2J
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Crystal Structure Of Human Naa50 In Complex With Accoa And An Inhibitor (Compound 4B) Identified Using Dna Encoded Library Technology
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2020-07-01 Classification: TRANSFERASE/INHIBITOR Ligands: ACO, U3Y |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-07-01
Ligands: ACO, U3Y
 |
Optimization Of Potent, Selective, And Orally Bioavailable Pyrrolodinopyrimidine-Containing Inhibitors Of Heat Shock Protein 90. Identification Of Development Candidate 2-Amino-4-{4-Chloro-2-[2-(4-Fluoro-1H-Pyrazol-1-Yl)Ethoxy]-6-Methylphenyl}-N-(2,2-Difluoropropyl)-5,7-Dihydro-6H-Pyrrolo[3,4-D]Pyrimidine-6-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2011-04-27 Classification: Chaperone/Chaperone inhibitor Ligands: WOE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-04-27
Ligands: WOE
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Optimization Of Potent, Selective, And Orally Bioavailable Pyrrolodinopyrimidine-Containing Inhibitors Of Heat Shock Protein 90. Identification Of Development Candidate 2-Amino-4-{4-Chloro-2-[2-(4-Fluoro-1H-Pyrazol-1-Yl)Ethoxy]-6-Methylphenyl}-N-(2,2-Difluoropropyl)-5,7-Dihydro-6H-Pyrrolo[3,4-D]Pyrimidine-6-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2011-04-27 Classification: Chaperone/Chaperone inhibitor Ligands: FU5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-04-27
Ligands: FU5
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Optimization Of Potent, Selective, And Orally Bioavailable Pyrrolodinopyrimidine-Containing Inhibitors Of Heat Shock Protein 90. Identification Of Development Candidate 2-Amino-4-{4-Chloro-2-[2-(4-Fluoro-1H-Pyrazol-1-Yl)Ethoxy]-6-Methylphenyl}-N-(2,2-Difluoropropyl)-5,7-Dihydro-6H-Pyrrolo[3,4-D]Pyrimidine-6-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2011-04-27 Classification: Chaperone/Chaperone inhibitor Ligands: FU3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-04-27
Ligands: FU3
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Optimization Of Potent, Selective, And Orally Bioavailable Pyrrolodinopyrimidine-Containing Inhibitors Of Heat Shock Protein 90. Identification Of Development Candidate 2-Amino-4-{4-Chloro-2-[2-(4-Fluoro-1H-Pyrazol-1-Yl)Ethoxy]-6-Methylphenyl}-N-(2,2-Difluoropropyl)-5,7-Dihydro-6H-Pyrrolo[3,4-D]Pyrimidine-6-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2011-04-27 Classification: Chaperone/Chaperone inhibitor Ligands: FU7, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-04-27
Ligands: FU7, PO4
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Hsp90 N-Terminal Domain In Complex With 4-Chloro-6-{[(2R)-2-(2-Methylphenyl)Pyrrolidin-1-Yl]Carbonyl}Benzene-1,3-Diol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2010-02-09 Classification: CHAPERONE Ligands: 4CD, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-02-09
Ligands: 4CD, DMS
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Hsp90 N-Terminal Domain In Complex With (1R)-2-(5-Chloro-2,4-Dihydroxybenzoyl)-N-Ethylisoindoline-1-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2010-02-09 Classification: CHAPERONE Ligands: 1RC, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-02-09
Ligands: 1RC, PO4
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Hsp90 N-Terminal Domain In Complex With 4-(1,3-Dihydro-2H-Isoindol-2-Ylcarbonyl)Benzene-1,3-Diol
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2010-02-09 Classification: CHAPERONE Ligands: PFT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-02-09
Ligands: PFT
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Hsp90 N-Terminal Domain In Complex With 1-{4-[(2R)-1-(5-Chloro-2,4-Dihydroxybenzoyl)Pyrrolidin-2-Yl]Benzyl}-3,3-Difluoropyrrolidinium
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.95 Å Release Date: 2009-09-29 Classification: CHAPERONE Ligands: BD0, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2009-09-29
Ligands: BD0, PO4
 |
Dihydroxylphenyl Amides As Inhibitors Of The Hsp90 Molecular Chaperone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.55 Å Release Date: 2008-11-25 Classification: CHAPERONE Ligands: PYU, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-11-25
Ligands: PYU, PO4
 |
Dihydroxylphenyl Amides As Inhibitors Of The Hsp90 Molecular Chaperone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2008-11-25 Classification: CHAPERONE Ligands: PY9, PO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-11-25
Ligands: PY9, PO4
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Human Vascular Endothelial Growth Factor Receptor 2 (Kdr) Kinase Domain
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2000-03-15 Classification: TRANSFERASE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2000-03-15