Search Count: 13
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Selective & Brain-Permeable Polo-Like Kinase-2 (Plk-2) Inhibitors That Reduce -Synuclein Phosphorylation In Rat Brain
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2013-12-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: R78 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-12-25
Ligands: R78
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Selective & Brain-Permeable Polo-Like Kinase-2 (Plk-2) Inhibitors That Reduce -Synuclein Phosphorylation In Rat Brain
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.74 Å Release Date: 2013-12-25 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1D1 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-12-25
Ligands: 1D1
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Selective & Brain-Permeable Polo-Like Kinase-2 (Plk-2) Inhibitors That Reduce -Synuclein Phosphorylation In Rat Brain
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2013-11-20 Classification: transferase/transferase inhibitor Ligands: 11G |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-11-20
Ligands: 11G
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Selective & Brain-Permeable Polo-Like Kinase-2 (Plk-2) Inhibitors That Reduce -Synuclein Phosphorylation In Rat Brain
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2013-11-20 Classification: transferase/transferase inhibitor Ligands: 1C7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-11-20
Ligands: 1C7
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Selective & Brain-Permeable Polo-Like Kinase-2 (Plk-2) Inhibitors That Reduce Alpha-Synuclein Phosphorylation In Rat Brain
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.91 Å Release Date: 2013-08-14 Classification: transferase/transferase inhibitor Ligands: 1C8 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-08-14
Ligands: 1C8
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Design And Synthesis Of Brain Penetrant Selective Jnk Inhibitors With Improved Pharmacokinetic Properties For The Prevention Of Neurodegeneration
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2013-05-08 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 34I |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-08
Ligands: 34I
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Highly Selective C-Jun N-Terminal Kinase (Jnk) 2 And 3 Inhibitors With In Vitro Cns-Like Pharmacokinetic Properties
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2011-08-17 Classification: transherase/transferase inhibitor Ligands: 589 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-08-17
Ligands: 589
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Design And Synthesis Of A Novel, Orally Efficacious Tri-Substituted Thiophene Based Jnk Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.43 Å Release Date: 2011-03-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 932 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-03-02
Ligands: 932
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Trypsin In Complex With The Inhibitor 1-[3-(Aminomethyl)Phenyl]-N-[3-Fluoro-2'-(Methylsulfonyl)Biphenyl-4-Yl]-3-(Trifluoromethyl)-1H-Pyrazole-5-Carboxamide (Dpc423)
Organism: Bos taurus
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2010-04-21 Classification: HYDROLASE Ligands: M35, CA |
Organism: Bos taurus
Method: X-RAY DIFFRACTION
Release Date: 2010-04-21
Ligands: M35, CA
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Factor Xa In Complex With The Inhibitor 1-[3-(Aminomethyl)Phenyl]-N-[3-Fluoro-2'-(Methylsulfonyl)Biphenyl-4-Yl]-3-(Trifluoromethyl)-1H-Pyrazole-5-Carboxamide (Dpc423)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2010-04-21 Classification: HYDROLASE Ligands: M35, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-04-21
Ligands: M35, CA
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Factor Xa In Complex With The Inhibitor 1-[2-(Aminomethyl)Phenyl]-N-(3-Fluoro-2'-Sulfamoylbiphenyl-4-Yl)-3-(Trifluoromethyl)-1H-Pyrazole-5-Carboxamide (Dpc602)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2010-04-21 Classification: HYDROLASE Ligands: M37, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2010-04-21
Ligands: M37, CA
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Factor Xa In Complex With The Inhibitor 3-(6-(2'-((Dimethylamino)Methyl)-4-Biphenylyl)-7-Oxo-3-(Trifluoromethyl)-4,5,6,7-Tetrahydro-1H-Pyrazolo[3,4-C]Pyridin-1-Yl)Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2006-10-03 Classification: HYDROLASE Ligands: 4QC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2006-10-03
Ligands: 4QC
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Factor Xa In Complex With The Inhibitor 1-(3-Amino-1,2-Benzisoxazol-5-Yl)-6-(2'-(((3R)-3-Hydroxy-1-Pyrrolidinyl)Methyl)-4-Biphenylyl)-3-(Trifluoromethyl)-1,4,5,6-Tetrahydro-7H-Pyrazolo[3,4-C]Pyridin-7-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2006-06-27 Classification: HYDROLASE Ligands: 5QC |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2006-06-27
Ligands: 5QC