Search Count: 10
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Design, Synthesis And Structure Activity Relationship Of Potent Pan-Pim Kinase Inhibitors Derived From The Pyridyl-Amide Scaffold
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2016-04-06 Classification: Transferase/Transferase Inhibitor Ligands: PEG, 6CB |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-04-06
Ligands: PEG, 6CB
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Identification Of N-(4-((1R,3S,5S)-3-Amino-5-Methylcyclohexyl)Pyridin-3-Yl)-6-(2,6-Difluorophenyl)-5-Fluoropicolinamide (Pim447), A Potent And Selective Proviral Insertion Site Of Moloney Murine Leukemia (Pim) 1,2 And 3 Kinase Inhibitor In Clinical Trials For Hematological Malignancies
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2015-11-11 Classification: Transferase/Transferase Inhibitor Ligands: 5H7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-11-11
Ligands: 5H7
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Rsk2 N-Terminal Kinase In Complex With Bi-D1870
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.55 Å Release Date: 2015-09-02 Classification: TRANSFERASE/TRANSFERASE Inhibitor Ligands: 584, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-02
Ligands: 584, GOL
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Rsk2 N-Terminal Kinase In Complex With Bis-Phenol Pyrazole
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2015-09-02 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: 583, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-09-02
Ligands: 583, GOL
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Rsk2 N-Terminal Kinase In Complex With 2-Amino-7-Substituted Benzoxazole Compound 8
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2014-02-19 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2NR |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-02-19
Ligands: 2NR
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Rsk2 N-Terminal Kinase In Complex With 2-Amino-7-Substituted Benzoxazole Compound 27
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.74 Å Release Date: 2014-02-19 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2NS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-02-19
Ligands: 2NS
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Pim1 Complexed With A Phenylcarboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2013-11-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2HV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-11-06
Ligands: 2HV
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Pim1 Complexed With A Pyridylcarboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2013-11-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2HW, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-11-06
Ligands: 2HW, GOL
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Pim1 Complexed With A Pyridylcarboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2013-11-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 2HX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-11-06
Ligands: 2HX
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Pim1 Complexed With A Novel 3,6-Disubstituted Indole At 2.6 Ang Resolution
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.60 Å Release Date: 2011-10-12 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3T9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-10-12
Ligands: 3T9