Search Count: 73
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Estrogen Receptor Alpha Ligand Binding Domain In Complex With A Complete Estrogen Receptor Antagonists That Favors Tetramer Formation
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.08 Å Release Date: 2025-08-27 Classification: TRANSCRIPTION Ligands: A1AI0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-08-27
Ligands: A1AI0
 |
Estrogen Receptor Alpha Ligand Binding Domain In Complex With Palazestrant
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2025-03-19 Classification: TRANSCRIPTION Ligands: A1AEA, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-03-19
Ligands: A1AEA, GOL
 |
Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant In Complex With (1'-(4-((1-Butylpyrrolidin-3-Yl)Methoxy)Phenyl)-6'-Hydroxy-1',4'-Dihydro-2'<I>H</I>-Spiro[Cyclopropane-1,3'-Isoquinolin]-2'-Yl)(Phenyl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2025-02-12 Classification: TRANSCRIPTION Ligands: HIS, TZI, A1BV9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-02-12
Ligands: HIS, TZI, A1BV9
 |
Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant In Complex With (6'-Hydroxy-1'-(4-(2-(1-Propylpyrrolidin-3-Yl)Ethoxy)Phenyl)-1',4'-Dihydro-2'<I>H</I>-Spiro[Cyclopropane-1,3'-Isoquinolin]-2'-Yl)(Phenyl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.98 Å Release Date: 2024-06-19 Classification: TRANSCRIPTION Ligands: TV3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-19
Ligands: TV3
 |
Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant In Complex With (6'-Hydroxy-1'-(4-((1-Propylazetidin-3-Yl)Methoxy)Phenyl)-1',4'-Dihydro-2'H-Spiro[Cyclopropane-1,3'-Isoquinolin]-2'-Yl)(Phenyl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2024-06-19 Classification: TRANSCRIPTION Ligands: A1ASN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-19
Ligands: A1ASN
 |
Estrogen Receptor Alpha Ligand Binding Domain In Complex With (6'-Hydroxy-1'-(4-(2-(Methylamino)Ethoxy)Phenyl)-1',4'-Dihydro-2'<I>H</I>-Spiro[Cyclopropane-1,3'-Isoquinolin]-2'-Yl)(Phenyl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2023-07-05 Classification: TRANSCRIPTION Ligands: TW6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-07-05
Ligands: TW6
 |
Estrogen Receptor Alpha Ligand Binding Domain In Complex With ((1'-(4-((1-Ethylpyrrolidin-3-Yl)Methyl)Phenyl)-6'-Hydroxy-1',4'-Dihydro-2'<I>H</I>-Spiro[Cyclopropane-1,3'-Isoquinolin]-2'-Yl)(Phenyl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.84 Å Release Date: 2022-11-16 Classification: TRANSCRIPTION Ligands: TTU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-11-16
Ligands: TTU
 |
Estrogen Receptor Alpha Ligand Binding Domain In Complex With (1'-(4-((1-Butylpyrrolidin-3-Yl)Methoxy)Phenyl)-6'-Hydroxy-1',4'-Dihydro-2'<I>H</I>-Spiro[Cyclopropane-1,3'-Isoquinolin]-2'-Yl)(Phenyl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.19 Å Release Date: 2022-11-16 Classification: TRANSCRIPTION Ligands: TZI |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-11-16
Ligands: TZI
 |
Estrogen Receptor Alpha Ligand Binding Domain In Complex With (1'-(4-((1-Ethylazetidin-3-Yl)Oxy)Phenyl)-6'-Hydroxy-1',4'-Dihydro-2'<I>H</I>-Spiro[Cyclopropane-1,3'-Isoquinolin]-2'-Yl)(Phenyl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2022-11-09 Classification: TRANSCRIPTION Ligands: TQF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-11-09
Ligands: TQF
 |
Estrogen Receptor Alpha Ligand Binding Domain In Complex With (6-Hydroxy-1-(4-((1-Propylazetidin-3-Yl)Oxy)Phenyl)-3,4-Dihydroisoquinolin-2(1H)-Yl)(Phenyl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.47 Å Release Date: 2022-11-09 Classification: TRANSCRIPTION Ligands: TS7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-11-09
Ligands: TS7
 |
Estrogen Receptor Alpha Ligand Binding Domain In Complex With (6-Hydroxy-1-(4-(2-(Piperidin-1-Yl)Ethoxy)Phenyl)-3,4-Dihydroisoquinolin-2(1H)-Yl)(Phenyl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2022-11-09 Classification: TRANSCRIPTION Ligands: TT5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-11-09
Ligands: TT5
 |
Estrogen Receptor Alpha Ligand Binding Domain In Complex With (1'-(4-(2-(1-Ethylpyrrolidin-3-Yl)Ethoxy)Phenyl)-6'-Hydroxy-1',4'-Dihydro-2'<I>H</I>-Spiro[Cyclopropane-1,3'-Isoquinolin]-2'-Yl)(Phenyl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2022-11-09 Classification: TRANSCRIPTION Ligands: TU9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-11-09
Ligands: TU9
 |
Estrogen Receptor Alpha Ligand Binding Domain In Complex With (6'-Hydroxy-1'-(4-(2-(1-Propylpyrrolidin-3-Yl)Ethoxy)Phenyl)-1',4'-Dihydro-2'<I>H</I>-Spiro[Cyclopropane-1,3'-Isoquinolin]-2'-Yl)(Phenyl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.81 Å Release Date: 2022-11-09 Classification: TRANSCRIPTION Ligands: TV3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-11-09
Ligands: TV3
 |
Estrogen Receptor Alpha Ligand Binding Domain In Complex With (6'-Hydroxy-1'-(4-(2-((<I>S</I>)-3-Methylpyrrolidin-1-Yl)Ethoxy)Phenyl)-1',4'-Dihydro-2'<I>H</I>-Spiro[Cyclopropane-1,3'-Isoquinolin]-2'-Yl)(Phenyl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.20 Å Release Date: 2022-11-09 Classification: TRANSCRIPTION Ligands: TVF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-11-09
Ligands: TVF
 |
Estrogen Receptor Alpha Ligand Binding Domain In Complex With (6'-Hydroxy-1'-(4-(2-((<I>R</I>)-2-Methylpyrrolidin-1-Yl)Ethoxy)Phenyl)-1',4'-Dihydro-2'<I>H</I>-Spiro[Cyclopropane-1,3'-Isoquinolin]-2'-Yl)(Phenyl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2022-11-09 Classification: TRANSCRIPTION Ligands: TVL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-11-09
Ligands: TVL
 |
Estrogen Receptor Alpha Ligand Binding Domain In Complex With (1'-(4-(2-(Dimethylamino)Ethoxy)Phenyl)-6'-Hydroxy-1',4'-Dihydro-2'<I>H</I>-Spiro[Cyclopropane-1,3'-Isoquinolin]-2'-Yl)(Phenyl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.04 Å Release Date: 2022-11-09 Classification: TRANSCRIPTION Ligands: TVX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-11-09
Ligands: TVX
 |
Estrogen Receptor Alpha Ligand Binding Domain In Complex With (1'-(4-(2-(Ethylamino)Ethoxy)Phenyl)-6'-Hydroxy-1',4'-Dihydro-2'<I>H</I>-Spiro[Cyclopropane-1,3'-Isoquinolin]-2'-Yl)(Phenyl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2022-11-09 Classification: TRANSCRIPTION Ligands: TWF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-11-09
Ligands: TWF
 |
Estrogen Receptor Alpha Ligand Binding Domain In Complex With (6'-Hydroxy-1'-(4-((1-Pentylpyrrolidin-3-Yl)Methoxy)Phenyl)-1',4'-Dihydro-2'<I>H</I>-Spiro[Cyclopropane-1,3'-Isoquinolin]-2'-Yl)(Phenyl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2022-11-09 Classification: TRANSCRIPTION Ligands: TX9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-11-09
Ligands: TX9
 |
Estrogen Receptor Alpha Ligand Binding Domain In Complex With (6'-Hydroxy-1'-(4-(2-(1-Propylpyrrolidin-3-Yl)Ethyl)Phenyl)-1',4'-Dihydro-2'<I>H</I>-Spiro[Cyclopropane-1,3'-Isoquinolin]-2'-Yl)(Phenyl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.59 Å Release Date: 2022-11-09 Classification: TRANSCRIPTION Ligands: TXK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-11-09
Ligands: TXK
 |
Estrogen Receptor Alpha Ligand Binding Domain In Complex With (6'-Hydroxy-1'-(4-((2-(1-Propylpyrrolidin-3-Yl)Ethyl)Thio)Phenyl)-1',4'-Dihydro-2'<I>H</I>-Spiro[Cyclopropane-1,3'-Isoquinolin]-2'-Yl)(Phenyl)Methanone
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2022-11-09 Classification: TRANSCRIPTION Ligands: TZ3 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-11-09
Ligands: TZ3