Search Count: 33
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 16 Bound To Egfr
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.51 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 2I0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 2I0
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 12 Bound To Egfrinsnpg
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.52 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 2I6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 2I6
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 22 Bound To Egfrinsnpg [V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.11 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 2EI, IOD |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 2EI, IOD
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 33 Bound To Egfrinsnpg [V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.28 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 26X |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 26X
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 18 Bound To Egfr[V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.13 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 2II |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 2II
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Discovery And Optimisation Of Potent, Efficacious And Selective Inhibitors Targeting Egfr Exon20 Insertion Mutations. Compound 33 Bound To Egfr[V948R]
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.62 Å Release Date: 2024-06-05 Classification: SIGNALING PROTEIN Ligands: 26X, ATP, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-06-05
Ligands: 26X, ATP, MG
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Crystal Structure Of Human Mat2A Bound To S-Adenosylmethionine And Compound 8
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.19 Å Release Date: 2024-03-20 Classification: TRANSFERASE Ligands: U74, SAM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-03-20
Ligands: U74, SAM
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Crystal Structure Of Human Mat2A Bound To S-Adenosylmethionine And Compound 11
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.16 Å Release Date: 2024-03-20 Classification: TRANSFERASE Ligands: U6R, SAM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-03-20
Ligands: U6R, SAM
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Crystal Structure Of Human Mat2A Bound To S-Adenosylmethionine And Compound 12
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.12 Å Release Date: 2024-03-20 Classification: TRANSFERASE Ligands: U8R, SAM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-03-20
Ligands: U8R, SAM
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Crystal Structure Of Human Mat2A Bound To S-Adenosylmethionine And Compound 15
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.10 Å Release Date: 2024-03-20 Classification: TRANSFERASE Ligands: U8E, SAM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-03-20
Ligands: U8E, SAM
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Crystal Structure Of Human Mat2A Bound To S-Adenosylmethionine And Compound 21
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.11 Å Release Date: 2024-03-20 Classification: TRANSFERASE Ligands: U7X, SAM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-03-20
Ligands: U7X, SAM
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Crystal Structure Of Human Mat2A Bound To S-Adenosylmethionine And Compound 31
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.09 Å Release Date: 2024-03-20 Classification: TRANSFERASE Ligands: U96, SAM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-03-20
Ligands: U96, SAM
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Krasg12C Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2023-07-12 Classification: SIGNALING PROTEIN Ligands: MG, GDP, PQI |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-07-12
Ligands: MG, GDP, PQI
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Krasg12C Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.11 Å Release Date: 2023-07-12 Classification: SIGNALING PROTEIN Ligands: MG, GDP, PUO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-07-12
Ligands: MG, GDP, PUO
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Krasg12C Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.18 Å Release Date: 2022-04-20 Classification: SIGNALING PROTEIN Ligands: V4T, MG, GDP, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-04-20
Ligands: V4T, MG, GDP, CA
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Krasg12C Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.38 Å Release Date: 2022-04-20 Classification: SIGNALING PROTEIN Ligands: MG, GDP, V52, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-04-20
Ligands: MG, GDP, V52, CA
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Krasg12C Ligand Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.48 Å Release Date: 2022-04-20 Classification: SIGNALING PROTEIN Ligands: MG, GDP, VLE, CA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-04-20
Ligands: MG, GDP, VLE, CA
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Crystal Structure Of Mat2A With Triazinone Fragment 1 Bound In The Allosteric Site
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.08 Å Release Date: 2021-04-21 Classification: TRANSFERASE Ligands: TQE, SAM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-04-21
Ligands: TQE, SAM
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Crystal Structure Of Mat2A With Quinazoline Fragment 2 Bound In The Allosteric Site
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.05 Å Release Date: 2021-04-21 Classification: TRANSFERASE Ligands: TNZ, SAM |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-04-21
Ligands: TNZ, SAM
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Crystal Structure Of Mat2A With Quinazolinone Fragment 5 Bound In The Allosteric Site
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.05 Å Release Date: 2021-04-21 Classification: TRANSFERASE Ligands: DMS, TO8, SAM, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-04-21
Ligands: DMS, TO8, SAM, CL