Structural Entry Filters:

Search Count: 35

9ZME image
Structure Of Ptp1B Complexed With Difluoromethylphosphonate Inhibitor Compound 2
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.73 Å Release Date: 2026-05-27
Classification: HYDROLASE/INHIBITOR
Ligands: A1C3A

9ZMF image
Structure Of Ptp1B Complexed With Difluoromethylphosphonate Inhibitor Compound 10
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.51 Å Release Date: 2026-05-27
Classification: HYDROLASE/INHIBITOR
Ligands: A1C3B

9ZMG image
Structure Of Ptp1B Complexed With Difluoromethylphosphonate Inhibitor Compound 15
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.15 Å Release Date: 2026-05-27
Classification: HYDROLASE/INHIBITOR
Ligands: A1C3C, DMS

9ZMH image
Structure Of Ptp1B Complexed With Difluoromethylphosphonate Inhibitor Compound 30
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.94 Å Release Date: 2026-05-27
Classification: HYDROLASE/INHIBITOR
Ligands: A1C3D

8V8H image
Pi3Ka H1047R Co-Crystal Structure With Inhibitor In Cryptic Pocket Near H1047R (Compound 4).
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:3.58 Å Release Date: 2024-03-20
Classification: SIGNALING PROTEIN
Ligands: YO4, YNZ

8V8I image
Pi3Ka H1047R Co-Crystal Structure With Inhibitor In Cryptic Pocket (Compound 5).
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:3.20 Å Release Date: 2024-03-20
Classification: SIGNALING PROTEIN
Ligands: YOR, YNZ, CL

8V8J image
Pi3Ka H1047R Co-Crystal Structure With Inhibitors In Two Cryptic Pockets (Compounds 4 And 5).
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:3.35 Å Release Date: 2024-03-20
Classification: SIGNALING PROTEIN
Ligands: YO4, YOR, YNZ

8V8U image
Pi3Ka H1047R Co-Crystal Structure With Inhibitor In Cryptic Pocket Near H1047R (Compound 12).
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.93 Å Release Date: 2024-03-20
Classification: SIGNALING PROTEIN
Ligands: 1LT, YQB

8V8V image
Pi3Ka H1047R Co-Crystal Structure With Inhibitor In Cryptic Pocket Near H1047R (Compound 7).
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.61 Å Release Date: 2024-03-20
Classification: SIGNALING PROTEIN
Ligands: YQ2, 1LT

7UOH image
Prmt5/Mep50 Crystal Structure With Mta And An Achiral, Class 1, Non-Atropisomeric Inhibitor Bound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.70 Å Release Date: 2022-08-17
Classification: TRANSFERASE
Ligands: NXF, MTA

7S1P image
Prmt5/Mep50 Crystal Structure With Sinefungin Bound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.21 Å Release Date: 2022-03-16
Classification: TRANSFERASE/INHIBITOR
Ligands: SFG

7T47 image
Kras G12D (Gppcp) With Mrtx-1133
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:1.27 Å Release Date: 2022-03-16
Classification: HYDROLASE/INHIBITOR
Ligands: 6IC, GCP, GDP, GOL, ACT, MG

7S0U image
Prmt5/Mep50 Crystal Structure With Mta And Phthalazinone Fragment Bound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.01 Å Release Date: 2022-01-26
Classification: TRANSFERASE
Ligands: CL, NA, EDO, 81X, MTA

7S1Q image
Prmt5/Mep50 Crystal Structure With Mta And A Phthalazinone Inhibitor Bound (Compound 9)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.78 Å Release Date: 2022-01-26
Classification: TRANSFERASE/INHIBITOR
Ligands: MTA, 84W

7S1R image
Prmt5/Mep50 Crystal Structure With Mta And A Phthalazinone Inhibitor Bound (Compound (M)-31)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.10 Å Release Date: 2022-01-26
Classification: TRANSFERASE/INHIBITOR
Ligands: MTA, 85E

7S1S image
Prmt5/Mep50 Crystal Structure With Mta And Mrtx-1719 Bound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.62 Å Release Date: 2022-01-26
Classification: TRANSFERASE/INHIBITOR
Ligands: MTA, 85K

7SER image
Prmt5/Mep50 With Compound 30 Bound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.14 Å Release Date: 2022-01-26
Classification: TRANSFERASE/INHIBITOR
Ligands: 97L, MTA

7SES image
Prmt5/Mep50 With Compound 29 Bound
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.50 Å Release Date: 2022-01-26
Classification: TRANSFERASE/INHIBITOR
Ligands: 97X, MTA

5KZ0 image
Structure Of Human Anaplastic Lymphoma Kinase In Complex With 2-[(1R)-1-{[2-Amino-5-(1,3-Dimethyl-1H-Pyrazol-4-Yl)Pyridin-3-Yl]Oxy}Ethyl]-4-Fluoro-N,N-Dimethylbenzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.30 Å Release Date: 2016-08-17
Classification: Transferase/Transferase Inhibitor
Ligands: 6YL

4UXL image
Structure Of Human Ros1 Kinase Domain In Complex With Pf-06463922
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Resolution:2.40 Å Release Date: 2015-03-11
Classification: TRANSFERASE
Ligands: 5P8
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