Search Count: 20
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.39 Å Release Date: 2022-11-23 Classification: HYDROLASE Ligands: ZN, 8IY |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2022-11-02 Classification: HYDROLASE Ligands: ZN, 98O |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2022-11-02 Classification: HYDROLASE Ligands: ZN, 99I |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:1.92 Å Release Date: 2022-11-02 Classification: HYDROLASE Ligands: ZN, 9DO |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2022-11-02 Classification: HYDROLASE Ligands: ZN, 9A1 |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.01 Å Release Date: 2022-11-02 Classification: HYDROLASE Ligands: ZN, 9B9 |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Escherichia coli (strain k12)
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2022-09-07 Classification: HYDROLASE Ligands: ZN, 7PX |
Organism: Escherichia coli (strain k12)
Method: X-RAY DIFFRACTION
Release Date: 2022-09-07
Ligands: ZN, 7PX
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2022-09-07 Classification: HYDROLASE Ligands: ZN, 7PX |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2022-09-07 Classification: HYDROLASE Ligands: ZN, 7S6 |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.04 Å Release Date: 2022-09-07 Classification: HYDROLASE Ligands: ZN, 7S2 |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2022-09-07 Classification: HYDROLASE Ligands: ZN, 7T5, EDO |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.55 Å Release Date: 2022-09-07 Classification: HYDROLASE Ligands: ZN, 7TF |
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Lpxc Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class Of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Organism: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2022-09-07 Classification: HYDROLASE Ligands: ZN, 6G8 |
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Chk1 Kinase Domain With Diazacarbazole Compound 8: N-[3-(6-Cyano-9H-Pyrrolo[2,3-B:5,4-C']Dipyridin-3-Yl)Phenyl]Acetamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2015-06-03 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3XK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-06-03
Ligands: 3XK
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Chk1 Kinase Domain With Diazacarbazole Compound 7: 3-(2-Hydroxyphenyl)-9H-Pyrrolo[2,3-B:5,4-C']Dipyridine-6-Carbonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2015-06-03 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3XL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-06-03
Ligands: 3XL
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Chk1 Kinase Domain With Diazacarbazole Compound 19
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.86 Å Release Date: 2015-06-03 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 3X7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2015-06-03
Ligands: 3X7
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Jak2 Kinase (Jh1 Domain) In Complex With The Inhibitor Trans-4-[(8As)-2-[(1R)-1-Hydroxyethyl]Imidazo[4,5-D]Pyrrolo[2,3-B]Pyridin-1(8Ah)-Yl]Cyclohexanecarbonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1J5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 1J5
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Jak1 Kinase (Jh1 Domain) In Complex With The Inhibitor Trans-4-{2-[(1R)-1-Hydroxyethyl]Imidazo[4,5-D]Pyrrolo[2,3-B]Pyridin-1(6H)-Yl}Cyclohexanecarbonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1J5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 1J5
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Jak1 Kinase (Jh1 Domain) In Complex With The Inhibitor (Trans-4-{2-[(1R)-1-Hydroxyethyl]Imidazo[4,5-D]Pyrrolo[2,3-B]Pyridin-1(6H)-Yl}Cyclohexyl)Acetonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1J6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 1J6
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Jak1 Kinase (Jh1 Domain) In Complex With Compound 34
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 15T |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 15T