Search Count: 11
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Cocrystal Of Brd4(D1) With N,N-Dimethyl-2-[(3R)-3-(5-{2-[2-Methyl-5-(Propan-2-Yl)Phenoxy]Pyrimidin-4-Yl}-4-[4-(Trifluoromethyl)Phenyl]-1H-Imidazol-1-Yl)Pyrrolidin-1-Yl]Ethan-1-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2022-01-19 Classification: GENE REGULATION/INHIBITOR Ligands: EDO, 2IR, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-19
Ligands: EDO, 2IR, CL
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Crystal Structure Of Brd4(D1) With 4-[4-(4-Bromophenyl)-1-(Piperidin-4-Yl)-1H-Imidazol-5-Yl]-N-(3,5-Dimethylphenyl)Pyrimidin-2-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.41 Å Release Date: 2022-01-19 Classification: GENE REGULATION/INHIBITOR Ligands: EDO, 7ZB |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-19
Ligands: EDO, 7ZB
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Crystal Of Brd4(D1) With 2-[(3S)-3-{5-[2-(3,5-Dimethylphenoxy)Pyrimidin-4-Yl]-4-(4-Iodophenyl)-1H-Imidazol-1-Yl}Pyrrolidin-1-Yl]Ethan-1-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.43 Å Release Date: 2022-01-19 Classification: GENE REGULATION/INHIBITOR Ligands: EDO, 7ZT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-19
Ligands: EDO, 7ZT
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Crystal Of Brd4(D1) With 2-[(3R)-3-{5-[2-(3,5-Dimethylphenoxy)Pyrimidin-4-Yl]-4-(4-Iodophenyl)-1H-Imidazol-1-Yl}Pyrrolidin-1-Yl]Ethan-1-Amine
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.68 Å Release Date: 2022-01-19 Classification: GENE REGULATION/INHIBITOR Ligands: 7ZK |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-01-19
Ligands: 7ZK
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Triazole-Based Bet Family Bromodomain Inhibitor Bound To Brd4(D1)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.42 Å Release Date: 2021-09-29 Classification: PROTEIN BINDING Ligands: YNS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-09-29
Ligands: YNS
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X-Ray Crystal Structure Of Human Brd4(D1) In Complex With 2-(4-{5-[6-(2,5-Dibromophenoxy)Pyridin-2-Yl]-4-Methyl-1H-1,2,3-Triazol-1-Yl}Piperidin-1-Yl)-N,N-Dimethylethan-1-Amine (Compound 26)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.32 Å Release Date: 2021-07-28 Classification: GENE REGULATION/INHIBITOR Ligands: EDO, ZHV, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-07-28
Ligands: EDO, ZHV, CL
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X-Ray Crystal Structure Of Human Brd4(D1) In Complex With 2-(4-{5-[6-(3,5-Dimethylphenoxy)Pyridin-2-Yl]-4-Methyl-1H-1,2,3-Triazol-1- Yl}Piperidin-1-Yl)-N,N-Dimethylethan-1-Amine (Dw34)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.20 Å Release Date: 2021-07-28 Classification: GENE REGULATION/INHIBITOR Ligands: EDO, ZHS, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-07-28
Ligands: EDO, ZHS, NA
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X-Ray Crystal Structure Of Human Brd4(D1) In Complex With 2-(2,5-Dibromophenoxy)-6-[4-Methyl-1-(Piperidin-4-Yl)-1H-1,2,3-Triazol-5-Yl]Pyridine (Compound 23)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.26 Å Release Date: 2021-07-28 Classification: GENE REGULATION/INHIBITOR Ligands: ZHM, EDO, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-07-28
Ligands: ZHM, EDO, CL
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Cocrystal Of Brd4(D1) With A Selective Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.53 Å Release Date: 2020-10-07 Classification: GENE REGULATION/INHIBITOR Ligands: EDO, U0D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-10-07
Ligands: EDO, U0D
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Crystal Structure Of The First Bromodomain Of Human Brd4 In Complex With Hu-10, A 1,4,5-Trisubstituted Imidazole Analogue
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2019-08-07 Classification: TRANSCRIPTION/TRANSCRIPTION INHIBITOR Ligands: JQP, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-08-07
Ligands: JQP, EDO
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Crystal Structure Of The First Bromodomain Of Human Brd4 In Complex With Skt-68, A 1,4,5-Trisubstituted Imidazole Analogue
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.74 Å Release Date: 2019-08-07 Classification: PROTEIN BINDING/INHIBITOR Ligands: JQY, DMS, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-08-07
Ligands: JQY, DMS, EDO