Search Count: 7
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Crystal Structure Of Human Kras G12C Covalently Bound To Thiazol-2-Yl Piperidine Compound 3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.45 Å Release Date: 2026-08-12 Classification: SIGNALING PROTEIN Ligands: MG, GDP, A1DI3, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-08-12
Ligands: MG, GDP, A1DI3, EDO
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Crystal Structure Of Human Kras G12C Covalently Bound To 4-Methyl-Thiazol-5-Yl Piperidine Compound 4
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.10 Å Release Date: 2026-08-12 Classification: SIGNALING PROTEIN Ligands: MG, GDP, A1DI5, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-08-12
Ligands: MG, GDP, A1DI5, EDO
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Crystal Structure Of Human Kras G12C Covalently Bound To 1,4-Dimethyl-Pyrazol-5-Yl Piperidine Compound 5
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.26 Å Release Date: 2026-08-12 Classification: SIGNALING PROTEIN Ligands: MG, GDP, A1DI6, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-08-12
Ligands: MG, GDP, A1DI6, EDO
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Crystal Structure Of Human Kras G12C Covalently Bound To Am-8719
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2026-08-12 Classification: SIGNALING PROTEIN Ligands: MG, GDP, A1DI7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-08-12
Ligands: MG, GDP, A1DI7
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Discovery Of Mta-Cooperative Prmt5 Inhibitors From Co-Factor Directed Dna-Encoded Library Screens
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.10 Å Release Date: 2025-05-07 Classification: TRANSFERASE/INHIBITOR Ligands: A1B6Y, MTA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-07
Ligands: A1B6Y, MTA
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From Dna-Encoded Library Screening To Am-9747 - An Mta-Cooperative Prmt5 Inhibitor With Potent Oral In Vivo Efficacy
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.25 Å Release Date: 2025-03-26 Classification: TRANSFERASE/INHIBITOR Ligands: A1BQW, MTA, GOL, PEG, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-03-26
Ligands: A1BQW, MTA, GOL, PEG, DMS
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Amg 193, A Clinical Stage Mta-Cooperative Prmt5 Inhibitor, Drives Anti-Tumor Activity Preclinically And In Patients With Mtap-Deleted Cancers
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.85 Å Release Date: 2024-10-02 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: GOL, DMS, A1ATH, MTA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2024-10-02
Ligands: GOL, DMS, A1ATH, MTA