Search Count: 9
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Identification Of The Clinical Development Candidate Mrtx849, A Covalent Krasg12C Inhibitor For The Treatment Of Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.27 Å Release Date: 2020-04-22 Classification: HYDROLASE/INHIBITOR Ligands: GDP, MG, M1R |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: GDP, MG, M1R
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Identification Of The Clinical Development Candidate Mrtx849, A Covalent Krasg12C Inhibitor For The Treatment Of Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.03 Å Release Date: 2020-04-22 Classification: HYDROLASE/INHIBITOR Ligands: GDP, MG, QH4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: GDP, MG, QH4
 |
Identification Of The Clinical Development Candidate Mrtx849, A Covalent Krasg12C Inhibitor For The Treatment Of Cancer
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.94 Å Release Date: 2020-04-22 Classification: HYDROLASE/INHIBITOR Ligands: GDP, MG, M1X |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: GDP, MG, M1X
 |
8-Tetrahydropyran-2-Yl Chromans: Highly Selective Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (Bace1) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2014-12-03 Classification: hydrolase/hydrolase inhibitor Ligands: NI, 3J9 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-03
Ligands: NI, 3J9
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8-Tetrahydropyran-2-Yl Chromans: Highly Selective Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (Bace1) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2014-12-03 Classification: hydrolase/hydrolase inhibitor Ligands: NI, 3UW |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-03
Ligands: NI, 3UW
 |
8-Tetrahydropyran-2-Yl Chromans: Highly Selective Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (Bace1) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2014-12-03 Classification: hydrolase/hydrolase inhibitor Ligands: NI, 3UX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-03
Ligands: NI, 3UX
 |
8-Tetrahydropyran-2-Yl Chromans: Highly Selective Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (Bace1) Inhibitors
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2014-12-03 Classification: hydrolase/hydrolase inhibitor Ligands: NI, 3UY |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-12-03
Ligands: NI, 3UY
 |
Discovery Of 7-Thp Chromans: Bace1 Inhibitors That Reduce A-Beta In The Cns
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2014-05-14 Classification: hydrolase/hydrolase inhibitor Ligands: NI, 2EX |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2014-05-14
Ligands: NI, 2EX
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Crystal Structure Of Human Coagulation Factor Xa Complexed With Fxv673
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2002-06-19 Classification: HYDROLASE Ligands: CA, FXV |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2002-06-19
Ligands: CA, FXV