Search Count: 33
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Crystal Structure Of Human Bcl6 Btb Domain In Complex With Compound Cct374705
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2023-04-26 Classification: TRANSCRIPTION Ligands: TWI, EDO, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2023-04-26
Ligands: TWI, EDO, CL
 |
Crystal Structure Of Human Bcl6 Btb Domain In Complex With Compound 12A
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2022-06-15 Classification: TRANSCRIPTION Ligands: EBL, CL, EDO, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2022-06-15
Ligands: EBL, CL, EDO, DMS
 |
Crystal Structure Of Human Bcl6 Btb Domain In Complex With Compound 4
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.67 Å Release Date: 2020-04-22 Classification: TRANSCRIPTION Ligands: NQE, EDO |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: NQE, EDO
 |
Crystal Structure Of Human Bcl6 Btb Domain In Complex With Compound 5
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.69 Å Release Date: 2020-04-22 Classification: TRANSCRIPTION Ligands: NQH, DMS, CL |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: NQH, DMS, CL
 |
Crystal Structure Of Human Bcl6 Btb Domain In Complex With Compound 6
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.58 Å Release Date: 2020-04-22 Classification: TRANSCRIPTION Ligands: NQK, EDO |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: NQK, EDO
 |
Crystal Structure Of Human Bcl6 Btb Domain In Complex With Compound 11F
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.58 Å Release Date: 2020-04-22 Classification: TRANSCRIPTION Ligands: NQN, EDO, DMS |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: NQN, EDO, DMS
 |
Crystal Structure Of Human Bcl6 Btb Domain In Complex With Compound 17A
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2020-04-22 Classification: TRANSCRIPTION Ligands: NQQ, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: NQQ, EDO
 |
Crystal Structure Of Human Bcl6 Btb Domain In Complex With Compound 23D
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.43 Å Release Date: 2020-04-22 Classification: TRANSCRIPTION Ligands: NQT, EDO, DMS |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: NQT, EDO, DMS
 |
Crystal Structure Of Human Bcl6 Btb Domain In Complex With Compound 25A
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.64 Å Release Date: 2020-04-22 Classification: TRANSCRIPTION Ligands: NQW, EDO, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: NQW, EDO, DMS
 |
Crystal Structure Of Human Bcl6 Btb Domain In Complex With Compound 1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2020-04-22 Classification: TRANSCRIPTION Ligands: NQZ, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: NQZ, EDO
 |
Crystal Structure Of Human Bcl6 Btb Domain In Complex With Compound 25B
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:2.36 Å Release Date: 2020-04-22 Classification: TRANSCRIPTION Ligands: NR5, EDO |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: NR5, EDO
 |
Crystal Structure Of Human Bcl6 Btb Domain In Complex With Compound 11A
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION Resolution:1.53 Å Release Date: 2020-04-22 Classification: TRANSCRIPTION Ligands: NR8, EDO |
Organism: Homo sapiens, Synthetic construct
Method: X-RAY DIFFRACTION
Release Date: 2020-04-22
Ligands: NR8, EDO
 |
Introduction Of A Methyl Group Curbs Metabolism Of Pyrido[3,4-D]Pyrimidine Mps1 Inhibitors And Enables The Discovery Of The Phase 1 Clinical Candidate Bos172722.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.48 Å Release Date: 2018-09-19 Classification: TRANSFERASE Ligands: FMW, 7PE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2018-09-19
Ligands: FMW, 7PE
 |
Rapid Discovery Of Pyrido[3,4-D]Pyrimidine Inhibitors Of Monopolar Spindle Kinase 1 (Mps1) Using A Structure-Based Hydridization Approach
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.66 Å Release Date: 2016-11-09 Classification: TRANSFERASE Ligands: 0SQ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-09
Ligands: 0SQ
 |
Rapid Discovery Of Pyrido[3,4-D]Pyrimidine Inhibitors Of Monopolar Spindle Kinase 1 (Mps1) Using A Structure-Based Hydridization Approach
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.18 Å Release Date: 2016-11-09 Classification: TRANSFERASE Ligands: 5O1, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-11-09
Ligands: 5O1, DMS
 |
Multi-Parameter Lead Optimization To Give An Oral Chk1 Inhibitor Clinical Candidate: (R)-5-((4-((Morpholin-2-Ylmethyl)Amino)-5-(Trifluoromethyl)Pyridin-2-Yl)Amino)Pyrazine-2-Carbonitrile (Cct245737)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.91 Å Release Date: 2016-05-25 Classification: TRANSFERASE Ligands: 5UY, EDO, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-05-25
Ligands: 5UY, EDO, GOL
 |
Rapid Discovery Of Pyrido[3,4-D]Pyrimidine Inhibitors Of Monopolar Spindle Kinase 1 (Mps1) Using A Structure-Based Hydridization Approach
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.18 Å Release Date: 2016-04-20 Classification: TRANSFERASE Ligands: 5NW, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-04-20
Ligands: 5NW, DMS
 |
Rapid Discovery Of Pyrido[3,4-D]Pyrimidine Inhibitors Of Monopolar Spindle Kinase 1 (Mps1) Using A Structure-Based Hydridization Approach
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.26 Å Release Date: 2016-04-20 Classification: TRANSFERASE Ligands: 7PE, 5O4, EDO, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-04-20
Ligands: 7PE, 5O4, EDO, DMS
 |
Rapid Discovery Of Pyrido[3,4-D]Pyrimidine Inhibitors Of Monopolar Spindle Kinase 1 (Mps1) Using A Structure-Based Hydridization Approach
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.67 Å Release Date: 2016-04-20 Classification: TRANSFERASE Ligands: 5O7 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-04-20
Ligands: 5O7
 |
Rapid Discovery Of Pyrido[3,4-D]Pyrimidine Inhibitors Of Monopolar Spindle Kinase 1 (Mps1) Using A Structure-Based Hydridization Approach
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.01 Å Release Date: 2016-04-20 Classification: TRANSFERASE Ligands: 5OQ, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2016-04-20
Ligands: 5OQ, DMS