Search Count: 8
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Discovery Of A Stable Macrocyclic O-Aminobenzamide Hsp90 Inhibitor Capable Of Significantly Decreasing Tumor Volume In A Mouse Xenograft Model.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.57 Å Release Date: 2011-07-13 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 06T |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-07-13
Ligands: 06T
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Discovery Of A Macrocyclic O-Aminobenzamide Hsp90 Inhibitor With Heterocyclic Tether That Shows Extended Biomarker Activity And In Vivo Efficacy In A Mouse Xenograft Model.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.58 Å Release Date: 2011-06-08 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 06J |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-06-08
Ligands: 06J
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Macrocyclic Lactams As Potent Hsp90 Inhibitors With Excellent Tumor Exposure And Extended Biomarker Activity.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.58 Å Release Date: 2011-05-11 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 06H |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-05-11
Ligands: 06H
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Design And Sar Of Macrocyclic Hsp90 Inhibitors With Increased Metabolic Stability And Potent Cell-Proliferation Activity
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.57 Å Release Date: 2011-04-06 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 05S, DMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2011-04-06
Ligands: 05S, DMS
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Complex Structure Of Insulin-Like Growth Factor Receptor And 3-Cyanoquinoline Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.90 Å Release Date: 2008-12-30 Classification: TRANSFERASE Ligands: 741 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-12-30
Ligands: 741
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Discovery Of Benzisoxazoles As Potent Inhibitors Of Chaperone Hsp90
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2008-07-08 Classification: CHAPERONE Ligands: BXZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-07-08
Ligands: BXZ
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Discovery Of Benzisoxazoles As Potent Inhibitors Of Chaperone Hsp90
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.60 Å Release Date: 2008-07-08 Classification: CHAPERONE Ligands: CXZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-07-08
Ligands: CXZ
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Complex Structure Of Insulin-Like Growth Factor Receptor And Isoquinolinedione Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2008-06-10 Classification: TRANSFERASE Ligands: 575 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2008-06-10
Ligands: 575