Search Count: 12
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Egfr Exon20 Insertion Mutant Asv Bound With (S)-3-((3-Chloro-2-Methoxyphenyl)Amino)-2-(3-((Tetrahydrofuran-2-Yl)Methoxy)Pyridin-4-Yl)-1,5,6,7-Tetrahydro-4H-Pyrrolo[3,2-C]Pyridin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2025-05-14 Classification: ONCOPROTEIN,TRANSFERASE/TRANSFERASE INHIBITOR Ligands: A1IMS, CL, EDO, GOL, PEG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: A1IMS, CL, EDO, GOL, PEG
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Egfr Exon20 Insertion Mutant Svd Bound With (S)-3-((3-Chloro-2-Methoxyphenyl)Amino)-2-(3-((Tetrahydrofuran-2-Yl)Methoxy)Pyridin-4-Yl)-1,5,6,7-Tetrahydro-4H-Pyrrolo[3,2-C]Pyridin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.68 Å Release Date: 2025-05-14 Classification: ONCOPROTEIN,TRANSFERASE/TRANSFERASE INHIBITOR Ligands: A1IMS, EDO, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: A1IMS, EDO, GOL
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Egfr Exon20 Insertion Mutant Svd Bound With Stx-721
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2025-05-14 Classification: ONCOPROTEIN,TRANSFERASE/TRANSFERASE INHIBITOR Ligands: A1A4E, CL, EDO, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: A1A4E, CL, EDO, GOL
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Wildtype Egfr Bound With (R)-3-((3-Chloro-2-Methoxyphenyl)Amino)-2-(3-((Tetrahydrofuran-2-Yl)Methoxy)Pyridin-4-Yl)-1,5,6,7-Tetrahydro-4H-Pyrrolo[3,2-C]Pyridin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:3.12 Å Release Date: 2025-05-14 Classification: ONCOPROTEIN Ligands: A1ILZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: A1ILZ
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Egfr Exon20 Insertion Mutant Npg Bound With (S)-3-((3-Chloro-2-Methoxyphenyl)Amino)-2-(3-((Tetrahydrofuran-2-Yl)Methoxy)Pyridin-4-Yl)-1,5,6,7-Tetrahydro-4H-Pyrrolo[3,2-C]Pyridin-4-One
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.88 Å Release Date: 2025-05-14 Classification: TRANSFERASE Ligands: A1IMS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: A1IMS
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Egfr Exon20 Insertion Mutant Npg Bound With Stx-721
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.63 Å Release Date: 2025-05-14 Classification: TRANSFERASE |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
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Wild-Type Egfr Bound With Stx-721
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.15 Å Release Date: 2025-05-14 Classification: TRANSFERASE Ligands: CL, A1IMT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-05-14
Ligands: CL, A1IMT
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Egfr Exon20 Insertion Mutant Npg Bound With Compound 23
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2025-01-29 Classification: TRANSFERASE Ligands: A1IEZ |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-29
Ligands: A1IEZ
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Egfr Exon20 Insertion Mutant Npg Bound With Compound 39
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.78 Å Release Date: 2025-01-29 Classification: TRANSFERASE Ligands: EDO, A1IE0 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-29
Ligands: EDO, A1IE0
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Wildtype Egfr Bound With Compound 23
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.06 Å Release Date: 2025-01-29 Classification: ONCOPROTEIN Ligands: DTT, A1IEZ, CL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2025-01-29
Ligands: DTT, A1IEZ, CL
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Crystal Structure Of Fgfr2 Kinase Domain Gatekeeper Mutant V564F In Complex With Covalent Compound 19
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.22 Å Release Date: 2021-02-10 Classification: SIGNALING PROTEIN Ligands: WFD, FLC, NA |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-02-10
Ligands: WFD, FLC, NA
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Crystal Structure Of Fgfr2 Kinase Domain Gatekeeper Mutant V564F In Complex With Covalent Compound 3
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.47 Å Release Date: 2021-02-10 Classification: SIGNALING PROTEIN Ligands: WF7, FLC, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2021-02-10
Ligands: WF7, FLC, GOL